Epstein-Barr virus-encoded LMP1 interacts with FGD4 to activate Cdc42 and thereby promote migration of nasopharyngeal carcinoma cells (Q34270437)

1 August 2017

Epstein-Barr virus-encoded LMP1 interacts with FGD4 to activate Cdc42 and thereby promote migration of nasopharyngeal carcinoma cells (English)

1 reference

1 August 2017

0 references

Hao-Ping Liu

1

1 reference

1 August 2017

Chia-Chun Chen

2

1 reference

1 August 2017

Chih-Ching Wu

3

1 reference

1 August 2017

Yi-Chuan Huang

4

1 reference

1 August 2017

Shu-Chen Liu

5

1 reference

1 August 2017

Ying Liang

6

1 reference

1 August 2017

Kai-Ping Chang

7

1 reference

1 August 2017

Yu-Sun Chang

8

1 reference

1 August 2017

10 May 2012

1 reference

1 August 2017

1 reference

1 August 2017

8

1 reference

1 August 2017

5

1 reference

1 August 2017

e1002690

1 reference

Creative Commons Attribution 4.0 International

1 August 2017

start time

10 May 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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6 July 2018

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6 July 2018

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Faciogenital dysplasia protein (FGD1) regulates export of cargo proteins from the golgi complex via Cdc42 activation

6 July 2018

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A novel Frabin (FGD4) nonsense mutation p.R275X associated with phenotypic variability in CMT4H.

6 July 2018

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Faciogenital dysplasia protein Fgd1 regulates invadopodia biogenesis and extracellular matrix degradation and is up-regulated in prostate and breast cancer

6 July 2018

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PAK signalling in neuronal physiology

6 July 2018

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The ghost in the machine: small GTPases as spatial regulators of exocytosis

6 July 2018

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The pathogen protein EspF(U) hijacks actin polymerization using mimicry and multivalency

6 July 2018

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Cellular signaling for activation of Rho GTPase Cdc42.

6 July 2018

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Frabin and other related Cdc42-specific guanine nucleotide exchange factors couple the actin cytoskeleton with the plasma membrane

6 July 2018

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Human immunodeficiency virus type 1 Nef recruits the guanine exchange factor Vav1 via an unexpected interface into plasma membrane microdomains for association with p21-activated kinase 2 activity

6 July 2018

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Peripheral nerve demyelination caused by a mutant Rho GTPase guanine nucleotide exchange factor, frabin/FGD4

6 July 2018

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Mutations in FGD4 encoding the Rho GDP/GTP exchange factor FRABIN cause autosomal recessive Charcot-Marie-Tooth type 4H

6 July 2018

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PRA1 promotes the intracellular trafficking and NF-kappaB signaling of EBV latent membrane protein 1

6 July 2018

1 reference

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GEF means go: turning on RHO GTPases with guanine nucleotide-exchange factors

6 July 2018

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Phosphatidylinositol 3-kinase and frabin mediate Cryptosporidium parvum cellular invasion via activation of Cdc42

6 July 2018

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Latent infection membrane protein transmembrane FWLY is critical for intermolecular interaction, raft localization, and signaling

6 July 2018

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Epstein-Barr virus latent membrane protein 1: structure and functions

6 July 2018

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LMP1, a viral relative of the TNF receptor family, signals principally from intracellular compartments

6 July 2018

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Microbial pathogenesis and cytoskeletal function.

6 July 2018

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Transmembrane domains 1 and 2 of the latent membrane protein 1 of Epstein-Barr virus contain a lipid raft targeting signal and play a critical role in cytostasis

6 July 2018

1 reference

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Rho GTPases in cell biology

6 July 2018

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The significance of LMP1 expression in nasopharyngeal carcinoma

6 July 2018

1 reference

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Epstein-Barr virus latent membrane protein 1 (LMP1) activates the phosphatidylinositol 3-kinase/Akt pathway to promote cell survival and induce actin filament remodeling

6 July 2018

1 reference

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CD40 and its viral mimic, LMP1: similar means to different ends

6 July 2018

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Guanine nucleotide exchange factors for Rho GTPases: turning on the switch

6 July 2018

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Establishment of two immortalized nasopharyngeal epithelial cell lines using SV40 large T and HPV16E6/E7 viral oncogenes.

6 July 2018

1 reference

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Association of frabin with specific actin and membrane structures.

6 July 2018

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Regulation of protein transport from the Golgi complex to the endoplasmic reticulum by CDC42 and N-WASP.

6 July 2018

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Association of the Epstein-Barr virus latent membrane protein 1 with lipid rafts is mediated through its N-terminal region

6 July 2018

1 reference

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Molecular determinants in pleckstrin homology domains that allow specific recognition of phosphoinositides

6 July 2018

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Cooperation of Cdc42 small G protein-activating and actin filament-binding activities of frabin in microspike formation

6 July 2018

1 reference

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CD40 and LMP-1 both signal from lipid rafts but LMP-1 assembles a distinct, more efficient signaling complex

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3349753

cdc42 regulates the exit of apical and basolateral proteins from the trans-Golgi network

6 July 2018

1 reference

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WASP and WAVE family proteins: key molecules for rapid rearrangement of cortical actin filaments and cell movement

6 July 2018

1 reference

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Epstein-Barr virus latent-infection membrane proteins are palmitoylated and raft-associated: protein 1 binds to the cytoskeleton through TNF receptor cytoplasmic factors

6 July 2018

1 reference

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Fgd1, the Cdc42 guanine nucleotide exchange factor responsible for faciogenital dysplasia, is localized to the subcortical actin cytoskeleton and Golgi membrane

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3349753

The interaction between Cdc42 and WASP is required for SDF-1-induced T-lymphocyte chemotaxis.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3349753

Asef, a link between the tumor suppressor APC and G-protein signaling

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3349753

Two actions of frabin: direct activation of Cdc42 and indirect activation of Rac.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3349753

Isolation, characterization, and mapping of the mouse Fgd3 gene, a new Faciogenital Dysplasia (FGD1; Aarskog Syndrome) gene homologue

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3349753

Isolation, characterization, and mapping of the mouse and human Fgd2 genes, faciogenital dysplasia (FGD1; Aarskog syndrome) gene homologues

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3349753

Activation of the small GTPase Cdc42 by the inflammatory cytokines TNF(alpha) and IL-1, and by the Epstein-Barr virus transforming protein LMP1.

6 July 2018

1 reference

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Ras-specific exchange factor GRF: oligomerization through its Dbl homology domain and calcium-dependent activation of Raf

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3349753

Latent membrane protein 1 of Epstein-Barr virus interacts with JAK3 and activates STAT proteins

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3349753

Frabin, a novel FGD1-related actin filament-binding protein capable of changing cell shape and activating c-Jun N-terminal kinase

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3349753

Pleckstrin homology domains: a common fold with diverse functions.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3349753

Direct stimulation of the guanine nucleotide exchange activity of p115 RhoGEF by Galpha13

6 July 2018

1 reference

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Activation of the cJun N-terminal kinase (JNK) pathway by the Epstein-Barr virus-encoded latent membrane protein 1 (LMP1).

6 July 2018

1 reference

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Epstein-Barr virus: LMP1 masquerades as an active receptor

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3349753

Latent membrane protein 1 of Epstein-Barr virus mimics a constitutively active receptor molecule.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3349753

The faciogenital dysplasia gene product FGD1 functions as a Cdc42Hs-specific guanine-nucleotide exchange factor

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3349753

Association of TRAF1, TRAF2, and TRAF3 with an Epstein-Barr virus LMP1 domain important for B-lymphocyte transformation: role in NF-kappaB activation

6 July 2018

1 reference

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Reproducibility of subjective immunohistochemical estrogen- and progesterone receptor determination in human endometrium.

6 July 2018

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Characterization of seven newly established nasopharyngeal carcinoma cell lines.

6 July 2018

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An EBV membrane protein expressed in immortalized lymphocytes transforms established rodent cells.

6 July 2018

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Transformation of Balb 3T3 cells by the BNLF-1 gene of Epstein-Barr virus

6 July 2018

1 reference

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Establishment and characterization of two nasopharyngeal carcinoma cell lines

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3349753

Morphological transformation of human keratinocytes expressing the LMP gene of Epstein Barr virus

6 July 2018

1 reference

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Epstein-Barr virus and carcinomas. Expression of the viral genome in an undifferentiated gastric carcinoma

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3349753

Two tumour necrosis factor receptors: structure and function.

6 July 2018

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Characterisation of the nucleotide exchange factor ITSN1L: evidence for a kinetic discrimination of GEF-stimulated nucleotide release from Cdc42.

21 January 2018

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Protein-DNA interactions at a drug-responsive element of the human apolipoprotein A-I gene

21 January 2018

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Histopathological Findings in Hereditary Motor and Sensory Neuropathy of Axonal Type With Onset in Early Childhood Associated WithMitofusin 2Mutations

21 January 2018

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12 December 2020

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Mammalian Cdc42 is a brefeldin A-sensitive component of the Golgi apparatus

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https://pubmed.ncbi.nlm.nih.gov/22589722

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12 December 2020

based on heuristic

Nasopharyngeal carcinoma in Taiwan clinical manifestations and results of therapy

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PubMed

https://pubmed.ncbi.nlm.nih.gov/22589722

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PPAT.1002690

1 reference

1 August 2017

1 reference

1 August 2017

1 reference