On the physiological importance of endoproteolysis of CAAX proteins: heart-specific RCE1 knockout mice develop a lethal cardiomyopathy. (Q34277651)

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21 December 2019

title

On the physiological importance of endoproteolysis of CAAX proteins: heart-specific RCE1 knockout mice develop a lethal cardiomyopathy (English)

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21 December 2019

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8

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21 December 2019

3

Bryant J Gavino

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21 December 2019

Hsiao D Lieu

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object named as

Hsiao D Lieu

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21 December 2019

author name string

Martin O Bergo

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21 December 2019

Patricia Ambroziak

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21 December 2019

James C Otto

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21 December 2019

Patrick J Casey

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21 December 2019

Quinn M Walker

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language of work or name

English

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publication date

18 November 2003

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Journal of Biological Chemistry

21 December 2019

published in

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21 December 2019

volume

279

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21 December 2019

issue

6

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21 December 2019

page(s)

4729-4736

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Protein lipidation in cell signaling

21 December 2019

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Modulation of Ras and a-factor function by carboxyl-terminal proteolysis

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Disruption of the mouse Rce1 gene results in defective Ras processing and mislocalization of Ras within cells

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RAM2, an essential gene of yeast, and RAM1 encode the two polypeptide components of the farnesyltransferase that prenylates a-factor and Ras proteins

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Inhibition of protein geranylgeranylation and RhoA/RhoA kinase pathway induces apoptosis in human endothelial cells

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A Yersinia effector and a Pseudomonas avirulence protein define a family of cysteine proteases functioning in bacterial pathogenesis.

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Absence of the CAAX endoprotease Rce1: effects on cell growth and transformation

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Gene recombination in postmitotic cells. Targeted expression of Cre recombinase provokes cardiac-restricted, site-specific rearrangement in adult ventricular muscle in vivo.

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21 January 2018

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Inducible inactivation of hepatic LRP gene by cre-mediated recombination confirms role of LRP in clearance of chylomicron remnants

21 January 2018

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Analysis of the role of microsomal triglyceride transfer protein in the liver of tissue-specific knockout mice

21 January 2018

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21 January 2018

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Conditional expression of a Gi-coupled receptor causes ventricular conduction delay and a lethal cardiomyopathy.

21 January 2018

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A polybasic domain or palmitoylation is required in addition to the CAAX motif to localize p21ras to the plasma membrane

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Endomembrane trafficking of ras: the CAAX motif targets proteins to the ER and Golgi

21 January 2018

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21 January 2018

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Signal transduction. How receptors turn Ras on.

21 January 2018

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Ventricular expression of a MLC-2v-ras fusion gene induces cardiac hypertrophy and selective diastolic dysfunction in transgenic mice.

21 January 2018

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A carboxyl-terminal interaction of lamin B1 is dependent on the CAAX endoprotease Rce1 and carboxymethylation

21 January 2018

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Missense mutations in the rod domain of the lamin A/C gene as causes of dilated cardiomyopathy and conduction-system disease

21 January 2018

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Farnesyltransferase inhibitors: antineoplastic properties, mechanisms of action, and clinical prospects

21 January 2018

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A farnesyltransferase inhibitor induces tumor regression in transgenic mice harboring multiple oncogenic mutations by mediating alterations in both cell cycle control and apoptosis

21 January 2018

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21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M310081200

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21 December 2019

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