Speed control: cogs and gears that drive the circadian clock (Q34285136)

1 August 2017

title

Speed control: cogs and gears that drive the circadian clock (English)

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1 August 2017

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Xiangzhong Zheng

1

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1 August 2017

Amita Sehgal

series ordinal

2

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1 August 2017

publication date

28 June 2012

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1 August 2017

published in

Trends in Neurosciences

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1 August 2017

volume

35

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1 August 2017

issue

9

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1 August 2017

page(s)

574-585

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Social jetlag and obesity

1 August 2017

cites work

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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Casein kinase 1-dependent phosphorylation of familial advanced sleep phase syndrome-associated residues controls PERIOD 2 stability

6 July 2018

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Disruption of circadian clocks has ramifications for metabolism, brain, and behavior

6 July 2018

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High-throughput chemical screen identifies a novel potent modulator of cellular circadian rhythms and reveals CKIα as a clock regulatory kinase

6 July 2018

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Drosophila pacemaker neurons require g protein signaling and GABAergic inputs to generate twenty-four hour behavioral rhythms

6 July 2018

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A hierarchical phosphorylation cascade that regulates the timing of PERIOD nuclear entry reveals novel roles for proline-directed kinases and GSK-3beta/SGG in circadian clocks.

6 July 2018

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Entrainment of disrupted circadian behavior through inhibition of casein kinase 1 (CK1) enzymes

6 July 2018

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AKT and TOR signaling set the pace of the circadian pacemaker

6 July 2018

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Circadian dysfunction in disease

6 July 2018

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Dynamic PER repression mechanisms in the Drosophila circadian clock: from on-DNA to off-DNA.

6 July 2018

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Essential roles of CKIdelta and CKIepsilon in the mammalian circadian clock

6 July 2018

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A serine cluster mediates BMAL1-dependent CLOCK phosphorylation and degradation

6 July 2018

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AMPK regulates the circadian clock by cryptochrome phosphorylation and degradation

6 July 2018

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CKIepsilon/delta-dependent phosphorylation is a temperature-insensitive, period-determining process in the mammalian circadian clock

6 July 2018

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Biological rhythms, higher brain function, and behavior: Gaps, opportunities, and challenges

6 July 2018

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A genome-wide RNAi screen for modifiers of the circadian clock in human cells

6 July 2018

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The effects of caffeine on sleep in Drosophila require PKA activity, but not the adenosine receptor.

6 July 2018

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Selective inhibition of casein kinase 1 epsilon minimally alters circadian clock period

6 July 2018

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Quantitative proteomics reveals a dynamic interactome and phase-specific phosphorylation in the Neurospora circadian clock

6 July 2018

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Casein kinase 1 delta regulates the pace of the mammalian circadian clock

6 July 2018

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Altered LARK expression perturbs development and physiology of the Drosophila PDF clock neurons

6 July 2018

1 reference

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A large-scale functional RNAi screen reveals a role for CK2 in the mammalian circadian clock.

6 July 2018

1 reference

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Adverse metabolic and cardiovascular consequences of circadian misalignment

6 July 2018

1 reference

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Ribosomal s6 kinase cooperates with casein kinase 2 to modulate the Drosophila circadian molecular oscillator.

6 July 2018

1 reference

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A chemical biology approach reveals period shortening of the mammalian circadian clock by specific inhibition of GSK-3beta

6 July 2018

1 reference

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Drosophila and vertebrate casein kinase Idelta exhibits evolutionary conservation of circadian function

6 July 2018

1 reference

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Human responses to the geophysical daily, annual and lunar cycles

6 July 2018

1 reference

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Activating PER repressor through a DBT-directed phosphorylation switch

6 July 2018

1 reference

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The phospho-occupancy of an atypical SLIMB-binding site on PERIOD that is phosphorylated by DOUBLETIME controls the pace of the clock.

6 July 2018

1 reference

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A circadian clock in Neurospora: how genes and proteins cooperate to produce a sustained, entrainable, and compensated biological oscillator with a period of about a day

6 July 2018

1 reference

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Circadian transcription contributes to core period determination in Drosophila

6 July 2018

1 reference

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Redundant function of REV-ERBalpha and beta and non-essential role for Bmal1 cycling in transcriptional regulation of intracellular circadian rhythms

6 July 2018

1 reference

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Widespread receptivity to neuropeptide PDF throughout the neuronal circadian clock network of Drosophila revealed by real-time cyclic AMP imaging

6 July 2018

1 reference

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A PER/TIM/DBT interval timer for Drosophila's circadian clock

6 July 2018

1 reference

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DEC1 modulates the circadian phase of clock gene expression

6 July 2018

1 reference

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Setting clock speed in mammals: the CK1 epsilon tau mutation in mice accelerates circadian pacemakers by selectively destabilizing PERIOD proteins

6 July 2018

1 reference

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Casein kinase I epsilon does not rescue double-time function in Drosophila despite evolutionarily conserved roles in the circadian clock

6 July 2018

1 reference

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High-fat diet disrupts behavioral and molecular circadian rhythms in mice

6 July 2018

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6 July 2018

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Drosophila DBT lacking protein kinase activity produces long-period and arrhythmic circadian behavioral and molecular rhythms

6 July 2018

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A seizure-prone phenotype is associated with altered free-running rhythm in Pten mutant mice

6 July 2018

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A functional genomics strategy reveals clockwork orange as a transcriptional regulator in the Drosophila circadian clock

6 July 2018

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Clockwork Orange is a transcriptional repressor and a new Drosophila circadian pacemaker component

6 July 2018

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Post-translational regulation of the Drosophila circadian clock requires protein phosphatase 1 (PP1)

6 July 2018

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Clockwork orange encodes a transcriptional repressor important for circadian-clock amplitude in Drosophila

6 July 2018

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The after-hours mutant reveals a role for Fbxl3 in determining mammalian circadian period

6 July 2018

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SCFFbxl3 controls the oscillation of the circadian clock by directing the degradation of cryptochrome proteins

6 July 2018

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Circadian mutant Overtime reveals F-box protein FBXL3 regulation of cryptochrome and period gene expression

6 July 2018

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LARK activates posttranscriptional expression of an essential mammalian clock protein, PERIOD1.

6 July 2018

1 reference

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Modeling of a human circadian mutation yields insights into clock regulation by PER2

6 July 2018

1 reference

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S6K1 regulates GSK3 under conditions of mTOR-dependent feedback inhibition of Akt.

6 July 2018

1 reference

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Differential effects of PER2 phosphorylation: molecular basis for the human familial advanced sleep phase syndrome (FASPS)

6 July 2018

1 reference

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An opposite role for tau in circadian rhythms revealed by mathematical modeling

6 July 2018

1 reference

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Protein phosphatase 1 regulates the stability of the circadian protein PER2.

6 July 2018

1 reference

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Drosophila CLOCK is constitutively expressed in circadian oscillator and non-oscillator cells

6 July 2018

1 reference

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PER-dependent rhythms in CLK phosphorylation and E-box binding regulate circadian transcription

6 July 2018

1 reference

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Constitutive expression of the Period1 gene impairs behavioral and molecular circadian rhythms

6 July 2018

1 reference

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Nuclear receptor Rev-erbalpha is a critical lithium-sensitive component of the circadian clock

6 July 2018

1 reference

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PER-TIM interactions in living Drosophila cells: an interval timer for the circadian clock

6 July 2018

1 reference

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Drosophila GPCR Han is a receptor for the circadian clock neuropeptide PDF.

6 July 2018

1 reference

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PDF receptor signaling in Drosophila contributes to both circadian and geotactic behaviors

6 July 2018

1 reference

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A role for glycogen synthase kinase-3beta in the mammalian circadian clock

6 July 2018

1 reference

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The double-time protein kinase regulates the subcellular localization of the Drosophila clock protein period

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434952

The orphan nuclear receptor RORalpha regulates circadian transcription of the mammalian core-clock Bmal1

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434952

Functional consequences of a CKIdelta mutation causing familial advanced sleep phase syndrome

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434952

Control of mammalian circadian rhythm by CKIepsilon-regulated proteasome-mediated PER2 degradation.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434952

A functional genomics strategy reveals Rora as a component of the mammalian circadian clock

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434952

Bidirectional role of orphan nuclear receptor RORalpha in clock gene transcriptions demonstrated by a novel reporter assay system.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434952

Posttranslational regulation of Drosophila PERIOD protein by protein phosphatase 2A.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434952

The doubletime and CKII kinases collaborate to potentiate Drosophila PER transcriptional repressor activity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434952

Drosophila doubletime mutations which either shorten or lengthen the period of circadian rhythms decrease the protein kinase activity of casein kinase I

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434952

Novel insights into the regulation of the timeless protein.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434952

vrille, Pdp1, and dClock form a second feedback loop in the Drosophila circadian clock

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434952

VRILLE feeds back to control circadian transcription of Clock in the Drosophila circadian oscillator

6 July 2018

1 reference

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A role for casein kinase 2alpha in the Drosophila circadian clock

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434952

Role for Slimb in the degradation of Drosophila Period protein phosphorylated by Doubletime.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434952

The orphan nuclear receptor REV-ERBalpha controls circadian transcription within the positive limb of the mammalian circadian oscillator

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434952

Control of intracellular dynamics of mammalian period proteins by casein kinase I epsilon (CKIepsilon) and CKIdelta in cultured cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434952

Posttranslational mechanisms regulate the mammalian circadian clock

6 July 2018

1 reference

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Phosphorylation of period is influenced by cycling physical associations of double-time, period, and timeless in the Drosophila clock.

6 July 2018

1 reference

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An hPer2 phosphorylation site mutation in familial advanced sleep phase syndrome

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434952

Lithium lengthens the circadian period of individual suprachiasmatic nucleus neurons

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434952

Isolation and analysis of six timeless alleles that cause short- or long-period circadian rhythms in Drosophila

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434952

Nuclear entry of the circadian regulator mPER1 is controlled by mammalian casein kinase I epsilon

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434952

A TIMELESS-independent function for PERIOD proteins in the Drosophila clock

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434952

Positional syntenic cloning and functional characterization of the mammalian circadian mutation tau.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434952

A pdf neuropeptide gene mutation and ablation of PDF neurons each cause severe abnormalities of behavioral circadian rhythms in Drosophila

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434952

Cycling vrille expression is required for a functional Drosophila clock

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434952

Familial advanced sleep-phase syndrome: A short-period circadian rhythm variant in humans

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434952

PER and TIM inhibit the DNA binding activity of a Drosophila CLOCK-CYC/dBMAL1 heterodimer without disrupting formation of the heterodimer: a basis for circadian transcription

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434952

Clock controls circadian period in isolated suprachiasmatic nucleus neurons

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434952

TIMELESS-dependent positive and negative autoregulation in the Drosophila circadian clock

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434952

The Drosophila clock gene double-time encodes a protein closely related to human casein kinase Iepsilon

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434952

double-time is a novel Drosophila clock gene that regulates PERIOD protein accumulation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434952

CYCLE is a second bHLH-PAS clock protein essential for circadian rhythmicity and transcription of Drosophila period and timeless

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434952

A mutant Drosophila homolog of mammalian Clock disrupts circadian rhythms and transcription of period and timeless

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434952

Closing the circadian loop: CLOCK-induced transcription of its own inhibitors per and tim.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434952

A circadian enhancer mediates PER-dependent mRNA cycling in Drosophila melanogaster

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434952

Functional identification of the mouse circadian Clock gene by transgenic BAC rescue

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434952

Effect of constant light and circadian entrainment of perS flies: evidence for light-mediated delay of the negative feedback loop in Drosophila.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434952

Regulation of nuclear entry of the Drosophila clock proteins period and timeless.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434952

A light-entrainment mechanism for the Drosophila circadian clock

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434952

Light-induced degradation of TIMELESS and entrainment of the Drosophila circadian clock.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434952

Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434952

A new biological rhythm mutant of Drosophila melanogaster that identifies a gene with an essential embryonic function

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434952

Mutagenesis and mapping of a mouse gene, Clock, essential for circadian behavior

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434952

Block in nuclear localization of period protein by a second clock mutation, timeless

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434952

Loss of circadian behavioral rhythms and per RNA oscillations in the Drosophila mutant timeless

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434952

Suppression of PERIOD protein abundance and circadian cycling by the Drosophila clock mutation timeless

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434952

Positional Cloning and Sequence Analysis of the Drosophila Clock Gene, timeless

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434952

Restoration of circadian behavioural rhythms by gene transfer in Drosophila

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434952

Molecular analysis of the period locus in Drosophila melanogaster and identification of a transcript involved in biological rhythms

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434952

P-element transformation with period locus DNA restores rhythmicity to mutant, arrhythmic drosophila melanogaster

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434952

Clock Mutants of Drosophila melanogaster

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434952

A Mutation of the Circadian System in Golden Hamsters

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434952

Changes in abundance or structure of the per gene product can alter periodicity of the Drosophila clock.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434952

Circadian fluctuations of period protein immunoreactivity in the CNS and the visual system of Drosophila.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434952

Genetic interaction of Per1 and Dec1/2 in the regulation of circadian locomotor activity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434952

Tuning the period of the mammalian circadian clock: additive and independent effects of CK1εTau and Fbxl3Afh mutations on mouse circadian behavior and molecular pacemaking.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434952

An isoform-specific mutant reveals a role of PDP1 epsilon in the circadian oscillator

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434952

Involvement of the protein kinase CK2 in the regulation of mammalian circadian rhythms.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434952

The neuropeptide pigment-dispersing factor adjusts period and phase of Drosophila's clock

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434952

Activation of 5'-AMP-activated kinase with diabetes drug metformin induces casein kinase Iepsilon (CKIepsilon)-dependent degradation of clock protein mPer2.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434952

Glycogen synthase kinase 3, circadian rhythms, and bipolar disorder: a molecular link in the therapeutic action of lithium

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434952

A G protein-coupled receptor, groom-of-PDF, is required for PDF neuron action in circadian behavior

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434952

The tau mutation in the Syrian hamster differentially reprograms the circadian clock in the SCN and peripheral tissues.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434952

Drosophila clock can generate ectopic circadian clocks

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434952

A role for CK2 in the Drosophila circadian oscillator

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434952

The F-box protein slimb controls the levels of clock proteins period and timeless

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434952

Sequential nuclear accumulation of the clock proteins period and timeless in the pacemaker neurons of Drosophila melanogaster.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434952

Clock mutation lengthens the circadian period without damping rhythms in individual SCN neurons

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434952

Drosophila CLOCK protein is under posttranscriptional control and influences light-induced activity.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434952

The Drosophila double-timeS mutation delays the nuclear accumulation of period protein and affects the feedback regulation of period mRNA.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434952

A role for the segment polarity gene shaggy/GSK-3 in the Drosophila circadian clock

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434952

Role of molecular oscillations in generating behavioral rhythms in Drosophila.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434952

Short-period mutations of per affect a double-time-dependent step in the Drosophila circadian clock.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434952

The 69 bp circadian regulatory sequence (CRS) mediates per-like developmental, spatial, and circadian expression and behavioral rescue in Drosophila.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434952

Altered circadian pacemaker functions and cyclic AMP rhythms in the Drosophila learning mutant dunce

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434952

Temporally regulated nuclear entry of the Drosophila period protein contributes to the circadian clock.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434952

Rhythmic expression of timeless: a basis for promoting circadian cycles in period gene autoregulation.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3434952

Two novel doubletime mutants alter circadian properties and eliminate the delay between RNA and protein in Drosophila

28 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22748426

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

dCLOCK is present in limiting amounts and likely mediates daily interactions between the dCLOCK-CYC transcription factor and the PER-TIM complex

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22748426

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Interlocked Feedback Loops Within the Drosophila Circadian Oscillator

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22748426

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.TINS.2012.05.007

1 reference

1 August 2017

1 reference

1 August 2017

1 reference