IDO is a nodal pathogenic driver of lung cancer and metastasis development (Q34289698)

1 August 2017

title

IDO is a nodal pathogenic driver of lung cancer and metastasis development (English)

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1 August 2017

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Courtney Smith

1

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1 August 2017

Mee Young Chang

2

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1 August 2017

Katherine H Parker

3

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1 August 2017

Daniel W Beury

4

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1 August 2017

James B DuHadaway

5

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Hollie E Flick

6

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1 August 2017

Janette Boulden

7

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1 August 2017

Erika Sutanto-Ward

8

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1 August 2017

Alejandro Peralta Soler

9

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1 August 2017

Lisa D Laury-Kleintop

10

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Laura Mandik-Nayak

11

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1 August 2017

Richard Metz

12

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1 August 2017

Suzanne Ostrand-Rosenberg

13

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George C Prendergast

14

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1 August 2017

Alexander J Muller

15

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1 August 2017

publication date

19 July 2012

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1 August 2017

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1 August 2017

volume

2

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1 August 2017

issue

8

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1 August 2017

page(s)

722-735

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An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor

1 August 2017

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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Hydroxyamidine inhibitors of indoleamine-2,3-dioxygenase potently suppress systemic tryptophan catabolism and the growth of IDO-expressing tumors

6 July 2018

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Kynurenic acid is a potent endogenous aryl hydrocarbon receptor ligand that synergistically induces interleukin-6 in the presence of inflammatory signaling

6 July 2018

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Tumor self-seeding by circulating cancer cells

6 July 2018

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Indoleamine 2,3-dioxygenase controls conversion of Foxp3+ Tregs to TH17-like cells in tumor-draining lymph nodes.

6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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SOCS3 drives proteasomal degradation of indoleamine 2,3-dioxygenase (IDO) and antagonizes IDO-dependent tolerogenesis

6 July 2018

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Chronic inflammation that facilitates tumor progression creates local immune suppression by inducing indoleamine 2,3 dioxygenase.

6 July 2018

1 reference

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Indoleamine 2,3-dioxygenase is the anticancer target for a novel series of potent naphthoquinone-based inhibitors.

6 July 2018

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Immune escape as a fundamental trait of cancer: focus on IDO.

6 July 2018

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Reduced inflammation in the tumor microenvironment delays the accumulation of myeloid-derived suppressor cells and limits tumor progression

6 July 2018

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Novel tryptophan catabolic enzyme IDO2 is the preferred biochemical target of the antitumor indoleamine 2,3-dioxygenase inhibitory compound D-1-methyl-tryptophan

6 July 2018

1 reference

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Oncogenic Ras-induced secretion of IL6 is required for tumorigenesis.

6 July 2018

1 reference

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Vascular endothelial growth factor and its relationship to inflammatory mediators

6 July 2018

1 reference

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Inhibition of indoleamine 2,3-dioxygenase in dendritic cells by stereoisomers of 1-methyl-tryptophan correlates with antitumor responses

6 July 2018

1 reference

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Targeting the mechanisms of tumoral immune tolerance with small-molecule inhibitors.

6 July 2018

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Upregulation of IFN-gamma receptor expression by proinflammatory cytokines influences IDO activation in epithelial cells

6 July 2018

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Inflammation induces myeloid-derived suppressor cells that facilitate tumor progression

6 July 2018

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K-ras activation generates an inflammatory response in lung tumors

6 July 2018

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6 July 2018

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Inhibition of indoleamine 2,3-dioxygenase, an immunoregulatory target of the cancer suppression gene Bin1, potentiates cancer chemotherapy.

6 July 2018

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Reduction of myeloid-derived suppressor cells and induction of M1 macrophages facilitate the rejection of established metastatic disease.

6 July 2018

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Indoleamine 2,3-dioxygenase expression is restricted to fetal trophoblast giant cells during murine gestation and is maternal genome specific

6 July 2018

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Evidence for a tumoral immune resistance mechanism based on tryptophan degradation by indoleamine 2,3-dioxygenase

6 July 2018

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Principles of interleukin (IL)-6-type cytokine signalling and its regulation

6 July 2018

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Analysis of lung tumor initiation and progression using conditional expression of oncogenic K-ras

6 July 2018

1 reference

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The C/EBP bZIP domain can mediate lipopolysaccharide induction of the proinflammatory cytokines interleukin-6 and monocyte chemoattractant protein-1.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677576

Prevention of allogeneic fetal rejection by tryptophan catabolism

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677576

Incorporation of adenovirus in calcium phosphate precipitates enhances gene transfer to airway epithelia in vitro and in vivo

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677576

Induction of pulmonary indoleamine 2,3-dioxygenase by interferon

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677576

Induction of indoleamine 2,3-dioxygenase: a mechanism of the antitumor activity of interferon gamma

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677576

Induction of indoleamine 2,3-dioxygenase in mouse lung during virus infection

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677576

A key in vivo antitumor mechanism of action of natural product-based brassinins is inhibition of indoleamine 2,3-dioxygenase

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677576

Local expression of indoleamine 2,3-dioxygenase protects engraftment of xenogeneic skin substitute

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677576

Joint effect of asthma/atopy and an IL-6 gene polymorphism on lung cancer risk among lifetime non-smoking Chinese women.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677576

Inflammation in the genesis and perpetuation of cancer: summary and recommendations from a national cancer institute-sponsored meeting.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677576

Cutting edge: silencing suppressor of cytokine signaling 3 expression in dendritic cells turns CD28-Ig from immune adjuvant to suppressant.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677576

Interleukin-6 -174G-->C polymorphism is associated with improved outcome in high-risk breast cancer

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677576

Resistance to metastatic disease in STAT6-deficient mice requires hemopoietic and nonhemopoietic cells and is IFN-gamma dependent.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3677576

Prostaglandin E2 promotes tumor progression by inducing myeloid-derived suppressor cells

28 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22822050

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Does postoperative serum interleukin-6 influence early recurrence after curative pulmonary resection of lung cancer?

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22822050

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

CD11b+/Gr-1+ immature myeloid cells mediate suppression of T cells in mice bearing tumors of IL-1beta-secreting cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22822050

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1158/2159-8290.CD-12-0014

1 reference

1 August 2017

1 reference

1 August 2017

1 reference