Sleeping beauty transposition: biology and applications for molecular therapy (Q34294570)

1 August 2017

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title

Sleeping beauty transposition: biology and applications for molecular therapy (English)

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1 August 2017

2

Zoltán Ivics

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1 August 2017

1

Zsuzsanna Izsvák

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1 August 2017

1 February 2004

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1 August 2017

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1 August 2017

9

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1 August 2017

2

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1 August 2017

147-156

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Viruses in therapy--royal road or dead end?

1 August 2017

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https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.11.009

Progress and problems with the use of viral vectors for gene therapy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.11.009

Outcry greets US plan to test smallpox vaccine on children

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.11.009

Progress and prospects: naked DNA gene transfer and therapy

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.11.009

Gene therapy progress and prospects: nonviral vectors.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.11.009

What restricts the activity of mariner-like transposable elements.

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.11.009

Initial sequencing and analysis of the human genome

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.11.009

Hot L1s account for the bulk of retrotransposition in the human population

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.11.009

An estimated frequency of endogenous insertional mutations in humans

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.11.009

LINE-mediated retrotransposition of marked Alu sequences

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.11.009

Alu repeats and human disease

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.11.009

Insertional mutagenesis of the Drosophila genome with single P elements

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.11.009

Identification of functional domains and evolution of Tc1-like transposable elements

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.11.009

Evidence for Drosophila P element transposase activity in mammalian cells and yeast

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.11.009

Transposition of the nematode Caenorhabditis elegans Tc3 element in the zebrafish Danio rerio.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.11.009

In vivo transposition of Minos, a Drosophila mobile element, in mammalian tissues

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.11.009

Molecular reconstruction of Sleeping Beauty, a Tc1-like transposon from fish, and its transposition in human cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.11.009

Regulated transposition of a fish transposon in the mouse germ line

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.11.009

Resident aliens: the Tc1/mariner superfamily of transposable elements

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.11.009

Helper-Independent Sleeping Beauty transposon-transposase vectors for efficient nonviral gene delivery and persistent gene expression in vivo

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.11.009

Sleeping Beauty, a wide host-range transposon vector for genetic transformation in vertebrates

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.11.009

Mammalian germ-line transgenesis by transposition.

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.11.009

Involvement of a bifunctional, paired-like DNA-binding domain and a transpositional enhancer in Sleeping Beauty transposition

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.11.009

A proposed superfamily of transposase genes: transposon-like elements in ciliated protozoa and a common "D35E" motif

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.11.009

Factors responsible for target site selection in Tn10 transposition: a role for the DDE motif in target DNA capture.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.11.009

The mechanism of transposition of Tc3 in C. elegans.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.11.009

Tiggers and DNA transposon fossils in the human genome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.11.009

Molecular evolution of the second ancient human mariner transposon, Hsmar2, illustrates patterns of neutral evolution in the human genome lineage

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.11.009

Molecular evolution of an ancient mariner transposon, Hsmar1, in the human genome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.11.009

The DNA-bending protein HMGB1 is a cellular cofactor of Sleeping Beauty transposition

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.11.009

Regulation of DNA-dependent activities by the functional motifs of the high-mobility-group chromosomal proteins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.11.009

High mobility group chromosomal protein 1 binds to the adeno-associated virus replication protein (Rep) and promotes Rep-mediated site-specific cleavage of DNA, ATPase activity and transcriptional repression

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.11.009

Retroviral cDNA integration: stimulation by HMG I family proteins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.11.009

Gene transfer into genomes of human cells by the sleeping beauty transposon system.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.11.009

Transposition and gene disruption in the male germline of the mouse

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.11.009

Chromosomal transposition of a Tc1/mariner-like element in mouse embryonic stem cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.11.009

Common physical properties of DNA affecting target site selection of sleeping beauty and other Tc1/mariner transposable elements.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.11.009

Target site selection in transposition

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.11.009

Requirement of RNA polymerase III transcription factors for in vitro position-specific integration of a retroviruslike element

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.11.009

The Saccharomyces retrotransposon Ty5 integrates preferentially into regions of silent chromatin at the telomeres and mating loci.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.11.009

Target site choice of the related transposable elements Tc1 and Tc3 of Caenorhabditis elegans

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.11.009

Somatic integration and long-term transgene expression in normal and haemophilic mice using a DNA transposon system

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.11.009

Gene insertion and long-term expression in lung mediated by the Sleeping Beauty transposon system

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.11.009

Efficient chromosomal transposition of a Tc1/mariner- like transposon Sleeping Beauty in mice.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.11.009

In vivo correction of murine tyrosinemia type I by DNA-mediated transposition.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.11.009

Sustainable correction of junctional epidermolysis bullosa via transposon-mediated nonviral gene transfer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.11.009

HIV-1 integration in the human genome favors active genes and local hotspots

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.11.009

AAV serotype 2 vectors preferentially integrate into active genes in mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.11.009

Chromosomal effects of adeno-associated virus vector integration

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.11.009

Characterization of two hypertransposing Tn5 mutants

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.11.009

Dominant transposition-deficient mutants of maize Activator (Ac) transposase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.11.009

Autoregulation of mariner transposase activity by overproduction and dominant-negative complementation.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.11.009

Characterization of the Caenorhabditis elegans Tc1 transposase in vivo and in vitro.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.11.009

A mechanism for Tn5 inhibition. carboxyl-terminal dimerization

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.11.009

Transposase titration in Drosophila melanogaster: a model of cytotype in the P-M system of hybrid dysgenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.11.009

The gene gun: current applications in cutaneous gene therapy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.11.009

Cationic transfection lipids in gene therapy: successes, set-backs, challenges and promises.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.11.009

Transposition from a gutless adeno-transposon vector stabilizes transgene expression in vivo

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.11.009

Stable integration of transgenes delivered by a retrotransposon-adenovirus hybrid vector

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.11.009

7 January 2021

The silence of the genes

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https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.11.009

Repeat-induced gene silencing in mammals.

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.11.009

Transposon-mediated single-copy gene delivery leads to increased transgene expression stability in barley.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.11.009

A serious adverse event after successful gene therapy for X-linked severe combined immunodeficiency

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.11.009

LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.11.009

Insulation from viral transcriptional regulatory elements enables improvement to hepatoma-specific gene expression from adenovirus vectors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.11.009

A chromatin insulator protects retrovirus vectors from chromosomal position effects

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.11.009

Controlling integration specificity of a yeast retrotransposon

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.11.009

The Frog Prince: a reconstructed transposon from Rana pipiens with high transpositional activity in vertebrate cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.11.009

Transcriptionally active genome regions are preferred targets for retrovirus integration.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.11.009

Mapping domains of retroviral integrase responsible for viral DNA specificity and target site selection by analysis of chimeras between human immunodeficiency virus type 1 and visna virus integrases

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.11.009

inferred from DOI database lookup

7 January 2021

based on heuristic

Integrating adenovirus-adeno-associated virus hybrid vectors devoid of all viral genes.

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2003.11.009

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/J.YMTHE.2003.11.009

1 reference

1 August 2017

1 reference

PubMed ID

14759798