Metal chelator decreases Alzheimer beta-amyloid plaques (Q34295910)

1 August 2017

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title

Metal chelator decreases Alzheimer beta-amyloid plaques (English)

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1 August 2017

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1

Gouras GK

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1 August 2017

Beal MF

2

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PubMed ID

11430794

1 August 2017

language of work or name

English

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publication date

1 June 2001

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1 August 2017

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1 August 2017

30

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1 August 2017

3

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1 August 2017

641-642

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BACE1 is the major beta-secretase for generation of Abeta peptides by neurons

1 August 2017

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https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900330-0

7 January 2021

Treatment with a copper-zinc chelator markedly and rapidly inhibits beta-amyloid accumulation in Alzheimer's disease transgenic mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900330-0

7 January 2021

Simvastatin strongly reduces levels of Alzheimer's disease beta -amyloid peptides Abeta 42 and Abeta 40 in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900330-0

7 January 2021

Ibuprofen suppresses plaque pathology and inflammation in a mouse model for Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900330-0

7 January 2021

A beta peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900330-0

7 January 2021

A beta peptide vaccination prevents memory loss in an animal model of Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900330-0

7 January 2021

Mice deficient in BACE1, the Alzheimer's beta-secretase, have normal phenotype and abolished beta-amyloid generation

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900330-0

7 January 2021

Soluble pool of Abeta amyloid as a determinant of severity of neurodegeneration in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900330-0

7 January 2021

New protease inhibitors prevent gamma-secretase-mediated production of Abeta40/42 without affecting Notch cleavage

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900330-0

7 January 2021

Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900330-0

7 January 2021

Intracellular APP processing and A beta production in Alzheimer disease

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900330-0

7 January 2021

TGF-beta1 promotes microglial amyloid-beta clearance and reduces plaque burden in transgenic mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0896-6273%2801%2900330-0

7 January 2021

10.1016/S0896-6273(01)00330-0

Identifiers

DOI

1 reference

1 August 2017

1 reference

PubMed ID

11430794