Leptin promotes the myofibroblastic phenotype in hepatic stellate cells by activating the hedgehog pathway. (Q34299086)

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13 February 2020

title

Leptin promotes the myofibroblastic phenotype in hepatic stellate cells by activating the hedgehog pathway (English)

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13 February 2020

1 reference

4

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13 February 2020

Gregory Michelotti

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13 February 2020

author name string

Steve S Choi

1

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13 February 2020

Wing-Kin Syn

2

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13 February 2020

Gamze F Karaca

3

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13 February 2020

Cynthia A Moylan

5

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13 February 2020

Rafal P Witek

6

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13 February 2020

Kolade M Agboola

7

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13 February 2020

Youngmi Jung

8

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13 February 2020

Anna Mae Diehl

10

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13 February 2020

language of work or name

English

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publication date

14 September 2010

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Journal of Biological Chemistry

13 February 2020

published in

1 reference

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13 February 2020

volume

285

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13 February 2020

issue

47

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13 February 2020

page(s)

36551-36560

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Activation of Rac1 promotes hedgehog-mediated acquisition of the myofibroblastic phenotype in rat and human hepatic stellate cells

13 February 2020

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Leptin induces phagocytosis of apoptotic bodies by hepatic stellate cells via a Rho guanosine triphosphatase-dependent mechanism

6 July 2018

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Accumulation of hedgehog-responsive progenitors parallels alcoholic liver disease severity in mice and humans

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Leptin affects endocardial cushion formation by modulating EMT and migration via Akt signaling cascades

6 July 2018

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Sonic hedgehog is an autocrine viability factor for myofibroblastic hepatic stellate cells

6 July 2018

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Leptin stimulates alpha1(I) collagen expression in human hepatic stellate cells via the phosphatidylinositol 3-kinase/Akt signalling pathway

6 July 2018

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In vitro and in vivo protection of stellate cells from apoptosis by leptin

6 July 2018

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Leptin promotes the proliferative response and invasiveness in human endometrial cancer cells by activating multiple signal-transduction pathways

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Obese and diabetic db/db mice develop marked liver fibrosis in a model of nonalcoholic steatohepatitis: role of short-form leptin receptors and osteopontin

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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Reduced nicotinamide adenine dinucleotide phosphate oxidase mediates fibrotic and inflammatory effects of leptin on hepatic stellate cells

21 January 2018

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Sustained activation of Rac1 in hepatic stellate cells promotes liver injury and fibrosis in mice.

21 January 2018

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Differential beta cell responses to hyperglycaemia and insulin resistance in two novel congenic strains of diabetes (FVB- Lepr (db)) and obese (DBA- Lep (ob)) mice

21 January 2018

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Leptin facilitates proliferation of hepatic stellate cells through up-regulation of platelet-derived growth factor receptor

21 January 2018

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21 January 2018

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28 October 2018

Identifiers

DOI

10.1074/JBC.M110.168542

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20843817%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20843817%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

PubMed publication ID

20843817

1 reference