A selective inhibitor of EZH2 blocks H3K27 methylation and kills mutant lymphoma cells (Q34302726)

1 August 2017

A selective inhibitor of EZH2 blocks H3K27 methylation and kills mutant lymphoma cells (English)

1 reference

1 August 2017

Joelle D Sacks

7

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ORCID Public Data File 2021

author name string

Sarah K Knutson

1

1 reference

1 August 2017

Tim J Wigle

2

1 reference

1 August 2017

Natalie M Warholic

3

1 reference

1 August 2017

Christopher J Sneeringer

4

1 reference

1 August 2017

Christina J Allain

5

1 reference

1 August 2017

Christine R Klaus

6

1 reference

1 August 2017

Alejandra Raimondi

8

1 reference

1 August 2017

Christina R Majer

9

1 reference

1 August 2017

Jeffrey Song

10

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1 August 2017

Margaret Porter Scott

11

1 reference

1 August 2017

Lei Jin

12

1 reference

1 August 2017

Jesse J Smith

13

1 reference

1 August 2017

Edward J Olhava

14

1 reference

1 August 2017

Richard Chesworth

15

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1 August 2017

Mikel P Moyer

16

1 reference

1 August 2017

Victoria M Richon

17

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1 August 2017

Robert A Copeland

18

1 reference

1 August 2017

Heike Keilhack

19

1 reference

1 August 2017

Roy M Pollock

20

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1 August 2017

Kevin W Kuntz

21

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1 August 2017

language of work or name

1 reference

30 September 2012

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1 August 2017

Nature Chemical Biology

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1 August 2017

8

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1 August 2017

890-896

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1 August 2017

11

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https://scigraph.springernature.com/pub.10.1038/nchembio.1084

1 August 2017

0 references

cites work

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UTX and JMJD3 are histone H3K27 demethylases involved in HOX gene regulation and development

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Identification of JmjC domain-containing UTX and JMJD3 as histone H3 lysine 27 demethylases

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Demethylation of H3K27 regulates polycomb recruitment and H2A ubiquitination

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EZH2 is a marker of aggressive breast cancer and promotes neoplastic transformation of breast epithelial cells

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Coordinated activities of wild-type plus mutant EZH2 drive tumor-associated hypertrimethylation of lysine 27 on histone H3 (H3K27) in human B-cell lymphomas

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PubMed

https://pubmed.ncbi.nlm.nih.gov/23023262

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

STUDIES ON LIVER ALCOHOL HYDROGENASE COMPLEXES. 3. MULTIPLE INHIBITION KINETICS IN THE PRESENCE OF TWO COMPETITIVE INHIBITORS

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PubMed

https://pubmed.ncbi.nlm.nih.gov/23023262

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NCHEMBIO.1084

1 reference

Dimensions Publication ID

1 August 2017

0 references

1 reference