Phosphorylated and sumoylation-deficient progesterone receptors drive proliferative gene signatures during breast cancer progression (Q34304234)

1 August 2017

Phosphorylated and sumoylation-deficient progesterone receptors drive proliferative gene signatures during breast cancer progression (English)

1 reference

1 August 2017

0 references

1 reference

1 reference

7

Carol A Lange

1 reference

1 August 2017

Todd P Knutson

1

1 reference

1 August 2017

Andrea R Daniel

2

1 reference

1 August 2017

Danhua Fan

3

1 reference

1 August 2017

Kevin At Silverstein

4

1 reference

1 August 2017

Kyle R Covington

5

1 reference

1 August 2017

Suzanne Aw Fuqua

6

1 reference

1 August 2017

14 June 2012

1 reference

1 August 2017

Breast Cancer Research

1 reference

1 August 2017

14

1 reference

1 August 2017

3

1 reference

1 August 2017

R95

1 reference

describes a project that uses

1 August 2017

limma

object named as

limma

2 references

22 June 2022

https://europepmc.org/article/PMC/3446358

inferred from PubMed Central ID database lookup

CZ Software Mentions: A large dataset of software mentions in the biomedical literature

affy

object named as

affy

1 reference

CZ Software Mentions: A large dataset of software mentions in the biomedical literature

exact match

https://scigraph.springernature.com/pub.10.1186/bcr3211

0 references

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ck2-dependent phosphorylation of progesterone receptors (PR) on Ser81 regulates PR-B isoform-specific target gene expression in breast cancer cells

6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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Growth factor signaling enhances aromatase activity of breast cancer cells via post-transcriptional mechanisms

6 July 2018

1 reference

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Differentiation-specific histone modifications reveal dynamic chromatin interactions and partners for the intestinal transcription factor CDX2

6 July 2018

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Estrogen plus progestin and breast cancer incidence and mortality in postmenopausal women

6 July 2018

1 reference

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Homeobox transcription factor muscle segment homeobox 2 (Msx2) correlates with good prognosis in breast cancer patients and induces apoptosis in vitro

6 July 2018

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A flexible R package for nonnegative matrix factorization

6 July 2018

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Nucleosome dynamics define transcriptional enhancers

6 July 2018

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6 July 2018

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1 reference

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Protein kinases mediate ligand-independent derepression of sumoylated progesterone receptors in breast cancer cells

6 July 2018

1 reference

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Biological determinants of endocrine resistance in breast cancer

6 July 2018

1 reference

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Signaling inputs to progesterone receptor gene regulation and promoter selectivity

6 July 2018

1 reference

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Ki67 index, HER2 status, and prognosis of patients with luminal B breast cancer

6 July 2018

1 reference

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DNA Binding Site Sequence Directs Glucocorticoid Receptor Structure and Activity

6 July 2018

1 reference

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DNA replication licensing and progenitor numbers are increased by progesterone in normal human breast

6 July 2018

1 reference

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Supervised risk predictor of breast cancer based on intrinsic subtypes

6 July 2018

1 reference

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Breast cancer after use of estrogen plus progestin in postmenopausal women

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446358

Msx2 induces epithelial-mesenchymal transition in mouse mammary epithelial cells through upregulation of Cripto-1.

6 July 2018

1 reference

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Androgen levels increase by intratumoral de novo steroidogenesis during progression of castration-resistant prostate cancer

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446358

SUMO-mediated inhibition of glucocorticoid receptor synergistic activity depends on stable assembly at the promoter but not on DAXX.

6 July 2018

1 reference

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FoxA1 translates epigenetic signatures into enhancer-driven lineage-specific transcription

6 July 2018

1 reference

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Differential recruitment of glucocorticoid receptor phospho-isoforms to glucocorticoid-induced genes

6 July 2018

1 reference

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Challenges to defining a role for progesterone in breast cancer

6 July 2018

1 reference

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Regulator of G-protein signalling 2 mRNA is differentially expressed in mammary epithelial subpopulations and over-expressed in the majority of breast cancers

6 July 2018

1 reference

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Validation of gene signatures that predict the response of breast cancer to neoadjuvant chemotherapy: a substudy of the EORTC 10994/BIG 00-01 clinical trial

6 July 2018

1 reference

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Concepts in sumoylation: a decade on

6 July 2018

1 reference

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Phosphorylation-dependent antagonism of sumoylation derepresses progesterone receptor action in breast cancer cells

6 July 2018

1 reference

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Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project

6 July 2018

1 reference

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High-resolution profiling of histone methylations in the human genome

6 July 2018

1 reference

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Definition of clinically distinct molecular subtypes in estrogen receptor-positive breast carcinomas through genomic grade

6 July 2018

1 reference

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Oncomine 3.0: genes, pathways, and networks in a collection of 18,000 cancer gene expression profiles

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446358

Distinct and predictive chromatin signatures of transcriptional promoters and enhancers in the human genome

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446358

Linkage of progestin and epidermal growth factor signaling: phosphorylation of progesterone receptors mediates transcriptional hypersensitivity and increased ligand-independent breast cancer cell growth

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446358

Insulin receptor substrates mediate distinct biological responses to insulin-like growth factor receptor activation in breast cancer cells.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446358

PIAS3 induction of PRB sumoylation represses PRB transactivation by destabilizing its retention in the nucleus

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446358

Identification of the MLL2 complex as a coactivator for estrogen receptor alpha

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446358

Sex steroid-producing enzymes in human breast cancer

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446358

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446358

Chromosome-wide mapping of estrogen receptor binding reveals long-range regulation requiring the forkhead protein FoxA1

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446358

Bim regulation of lumen formation in cultured mammary epithelial acini is targeted by oncogenes.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446358

Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: an overview of the randomised trials

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446358

MatInspector and beyond: promoter analysis based on transcription factor binding sites

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446358

Genetic variation in the progesterone receptor gene and ovarian cancer risk

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446358

A multigene assay to predict recurrence of tamoxifen-treated, node-negative breast cancer

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446358

Progesterone-independent effects of human progesterone receptors (PRs) in estrogen receptor-positive breast cancer: PR isoform-specific gene regulation and tumor biology.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446358

Bioconductor: open software development for computational biology and bioinformatics

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446358

Msx-1 and Msx-2 in mammary gland development

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446358

High density DNA microarrays: algorithms and biomedical applications

6 July 2018

1 reference

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How do site-specific DNA-binding proteins find their targets?

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446358

Mammalian stanniocalcins and cancer

6 July 2018

1 reference

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Breast cancer and hormone-replacement therapy in the Million Women Study

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446358

Influence of estrogen plus progestin on breast cancer and mammography in healthy postmenopausal women: the Women's Health Initiative Randomized Trial

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446358

PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446358

Gene expression phenotypic models that predict the activity of oncogenic pathways

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446358

Progesterone and Glucocorticoid Receptors Recruit Distinct Coactivator Complexes and Promote Distinct Patterns of Local Chromatin Modification

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446358

CBP recruitment and histone acetylation in differential gene induction by glucocorticoids and progestins

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446358

Summaries of Affymetrix GeneChip probe level data

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446358

Heregulin induces transcriptional activation of the progesterone receptor by a mechanism that requires functional ErbB-2 and mitogen-activated protein kinase activation in breast cancer cells.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446358

A functional polymorphism in the promoter of the progesterone receptor gene associated with endometrial cancer risk

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446358

Gene expression profiling predicts clinical outcome of breast cancer

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446358

Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446358

Progestin effects on long-term growth, death, and Bcl-xL in breast cancer cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446358

SUMO--nonclassical ubiquitin

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446358

Molecular portraits of human breast tumours

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446358

A common motif within the negative regulatory regions of multiple factors inhibits their transcriptional synergy

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446358

Msx2 deficiency in mice causes pleiotropic defects in bone growth and ectodermal organ formation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446358

Phosphorylation of human progesterone receptors at serine-294 by mitogen-activated protein kinase signals their degradation by the 26S proteasome

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446358

Differential hormone-dependent phosphorylation of progesterone receptor A and B forms revealed by a phosphoserine site-specific monoclonal antibody

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446358

Possible involvement of MSX-2 homeoprotein in v-ras-induced transformation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446358

The transcriptional coactivators p300 and CBP are histone acetyltransferases

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446358

Role of phosphorylation on DNA binding and transcriptional functions of human progesterone receptors

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446358

Epidermal growth factor-related peptides activate distinct subsets of ErbB receptors and differ in their biological activities

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446358

New T47D breast cancer cell lines for the independent study of progesterone B- and A-receptors: only antiprogestin-occupied B-receptors are switched to transcriptional agonists by cAMP.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446358

Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3446358

Association of the Progesterone Receptor Gene with Breast Cancer Risk: A Single-Nucleotide Polymorphism Tagging Approach

6 July 2018

1 reference

Variant T47D human breast cancer cells with high progesterone-receptor levels despite estrogen and antiestrogen resistance.

21 January 2018

1 reference

Differential gene regulation by the two progesterone receptor isoforms in human breast cancer cells

21 January 2018

1 reference

The use of ATP bioluminescence as a measure of cell proliferation and cytotoxicity

21 January 2018

1 reference

Progesterone receptor is a significant factor associated with clinical outcomes and effect of adjuvant tamoxifen therapy in breast cancer patients

21 January 2018

1 reference

Progestin-dependent progression of human breast tumor xenografts: a novel model for evaluating antitumor therapeutics

21 January 2018

1 reference

Exemestane for breast-cancer prevention in postmenopausal women.

21 January 2018

1 reference

Lapatinib combined with letrozole versus letrozole and placebo as first-line therapy for postmenopausal hormone receptor-positive metastatic breast cancer

21 January 2018

1 reference

Progesterone receptor action: defining a role in breast cancer

21 January 2018

1 reference

A module of negative feedback regulators defines growth factor signaling

21 January 2018

1 reference

Inhibition of in vivo breast cancer growth by antisense oligodeoxynucleotides to type I insulin-like growth factor receptor mRNA involves inactivation of ErbBs, PI-3K/Akt and p42/p44 MAPK signaling pathways but not modulation of progesterone recepto

21 January 2018

1 reference

Trastuzumab plus anastrozole versus anastrozole alone for the treatment of postmenopausal women with human epidermal growth factor receptor 2-positive, hormone receptor-positive metastatic breast cancer: results from the randomized phase III TAnDEM

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22697792

12 December 2020

inferred from PubMed ID database lookup

Progesterone enhances branching morphogenesis in the mouse mammary gland by increased expression of Msx2

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22697792

12 December 2020

inferred from PubMed ID database lookup

ErbB2/neu kinase modulates cellular p27(Kip1) and cyclin D1 through multiple signaling pathways

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22697792

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1186/BCR3211

1 reference

Dimensions Publication ID

1 August 2017

0 references

1 reference

1 August 2017

1 reference