The structure of the MAPK scaffold, MP1, bound to its partner, p14. A complex with a critical role in endosomal map kinase signaling (Q34305323)

1 August 2017

The structure of the MAPK scaffold, MP1, bound to its partner, p14. A complex with a critical role in endosomal map kinase signaling (English)

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1 August 2017

5

Miroslaw Cygler

1 reference

1 August 2017

Vladimir V Lunin

1

1 reference

1 August 2017

Christine Munger

2

1 reference

1 August 2017

John Wagner

3

1 reference

1 August 2017

Zheng Ye

4

1 reference

1 August 2017

Michael Sacher

6

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1 August 2017

language of work or name

English

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publication date

11 March 2004

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Journal of Biological Chemistry

1 August 2017

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1 August 2017

279

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1 August 2017

22

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1 August 2017

23422-23430

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Signaling through scaffold, anchoring, and adaptor proteins

1 August 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401648200

Meaningful relationships: the regulation of the Ras/Raf/MEK/ERK pathway by protein interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401648200

Organization and regulation of mitogen-activated protein kinase signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401648200

Nuclear translocation of p42/p44 mitogen-activated protein kinase is required for growth factor-induced gene expression and cell cycle entry

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401648200

The Raf/MEK/ERK pathway: new concepts of activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401648200

Regulation of MAP Kinase Signaling Modules by Scaffold Proteins in Mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401648200

KSR is a scaffold required for activation of the ERK/MAPK module

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401648200

Activation and targeting of extracellular signal-regulated kinases by beta-arrestin scaffolds

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401648200

MP1: a MEK binding partner that enhances enzymatic activation of the MAP kinase cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401648200

KSR-1 binds to G-protein betagamma subunits and inhibits beta gamma-induced mitogen-activated protein kinase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401648200

KSR modulates signal propagation within the MAPK cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401648200

Regulation of the MAP kinase pathway by mammalian Ksr through direct interaction with MEK and ERK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401648200

Kinase suppressor of Ras forms a multiprotein signaling complex and modulates MEK localization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401648200

beta-arrestin-dependent endocytosis of proteinase-activated receptor 2 is required for intracellular targeting of activated ERK1/2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401648200

A novel 14-kilodalton protein interacts with the mitogen-activated protein kinase scaffold mp1 on a late endosomal/lysosomal compartment

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401648200

Localization of the MP1-MAPK scaffold complex to endosomes is mediated by p14 and required for signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401648200

Automated MAD and MIR structure solution

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401648200

Automated side-chain model building and sequence assignment by template matching

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401648200

Refinement of macromolecular structures by the maximum-likelihood method

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401648200

Automated protein model building combined with iterative structure refinement

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401648200

Improved methods for building protein models in electron density maps and the location of errors in these models

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401648200

PROCHECK: a program to check the stereochemical quality of protein structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401648200

Dali: a network tool for protein structure comparison

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401648200

A novel snare N-terminal domain revealed by the crystal structure of Sec22b

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401648200

An autoinhibitory mechanism for nonsyntaxin SNARE proteins revealed by the structure of Ykt6p

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401648200

Molecular architecture and functional model of the endocytic AP2 complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401648200

Crystal structure of SEDL and its implications for a genetic disease spondyloepiphyseal dysplasia tarda

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401648200

Structural basis for the function of the beta subunit of the eukaryotic signal recognition particle receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401648200

SCOP: a structural classification of proteins database

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401648200

Identification and characterization of five new subunits of TRAPP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401648200

SNAP receptors implicated in vesicle targeting and fusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401648200

Interaction of tyrosine-based sorting signals with clathrin-associated proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401648200

Assigning genomic sequences to CATH

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401648200

Drosophila roadblock and Chlamydomonas LC7: a conserved family of dynein-associated proteins involved in axonal transport, flagellar motility, and mitosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401648200

Dynein light chains of the Roadblock/LC7 group belong to an ancient protein superfamily implicated in NTPase regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401648200

The InterPro database, an integrated documentation resource for protein families, domains and functional sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401648200

The MEK1 proline-rich insert is required for efficient activation of the mitogen-activated protein kinases ERK1 and ERK2 in mammalian cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401648200

A proline-rich sequence unique to MEK1 and MEK2 is required for raf binding and regulates MEK function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401648200

Crystal structure of beta-arrestin at 1.9 A: possible mechanism of receptor binding and membrane Translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401648200

Scaffolding functions of arrestin-2 revealed by crystal structure and mutagenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401648200

Endosomal signaling of epidermal growth factor receptor stimulates signal transduction pathways leading to cell survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401648200

Signal transduction and endocytosis: close encounters of many kinds

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401648200

The odd couple: signal transduction and endocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401648200

Signal transduction mediated by the Ras/Raf/MEK/ERK pathway from cytokine receptors to transcription factors: potential targeting for therapeutic intervention.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401648200

Ras/Raf signalling and emerging pharmacotherapeutic targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401648200

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401648200

Raster3D: photorealistic molecular graphics

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401648200

Structural organization of MAP-kinase signaling modules by scaffold proteins in yeast and mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M401648200

21 January 2018

Identifiers

DOI

10.1074/JBC.M401648200

1 reference

1 August 2017

1 reference