Phosphorylation of p65(RelA) on Ser(547) by ATM represses NF-κB-dependent transcription of specific genes after genotoxic stress (Q34310237)

1 August 2017

Phosphorylation of p65(RelA) on Ser(547) by ATM represses NF-κB-dependent transcription of specific genes after genotoxic stress (English)

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1 August 2017

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4

Franck Dequiedt

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author name string

Hélène Sabatel

1

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1 August 2017

Emmanuel Di Valentin

2

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1 August 2017

Geoffrey Gloire

3

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1 August 2017

Jacques Piette

5

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1 August 2017

Yvette Habraken

6

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1 August 2017

language of work or name

English

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publication date

8 June 2012

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1 August 2017

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1 August 2017

7

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1 August 2017

6

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1 August 2017

e38246

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Creative Commons Attribution 4.0 International

1 August 2017

start time

8 June 2012

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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ATM- and NEMO-dependent ELKS ubiquitination coordinates TAK1-mediated IKK activation in response to genotoxic stress

6 July 2018

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NF-kappaB as a critical link between inflammation and cancer

6 July 2018

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6 July 2018

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Thr435 phosphorylation regulates RelA (p65) NF-kappaB subunit transactivation

6 July 2018

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6 July 2018

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6 July 2018

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Shared principles in NF-kappaB signaling

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ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage

6 July 2018

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Integrating cell-signalling pathways with NF-kappaB and IKK function

6 July 2018

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Mutations in the NF-kappaB signaling pathway: implications for human disease

6 July 2018

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Post-translational modifications regulating the activity and function of the nuclear factor kappa B pathway

6 July 2018

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NF-kappaB activation by double-strand breaks

6 July 2018

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Differential regulation of NF-kappaB activation and function by topoisomerase II inhibitors

6 July 2018

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Molecular linkage between the kinase ATM and NF-kappaB signaling in response to genotoxic stimuli

6 July 2018

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IkappaB kinase alpha-mediated derepression of SMRT potentiates acetylation of RelA/p65 by p300.

6 July 2018

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Identification of novel and cell type enriched cofactors of the transcription activation domain of RelA (p65 NF-kappaB).

6 July 2018

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DNA damage-induced association of ATM with its target proteins requires a protein interaction domain in the N terminus of ATM.

6 July 2018

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6 July 2018

Signaling to NF-kappaB

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The immunobiology of cancer immunosurveillance and immunoediting

6 July 2018

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p53 induces NF-kappaB activation by an IkappaB kinase-independent mechanism involving phosphorylation of p65 by ribosomal S6 kinase 1.

6 July 2018

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Sequential modification of NEMO/IKKgamma by SUMO-1 and ubiquitin mediates NF-kappaB activation by genotoxic stress

6 July 2018

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TAK1 is critical for IkappaB kinase-mediated activation of the NF-kappaB pathway

6 July 2018

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ATM is required for IkappaB kinase (IKKk) activation in response to DNA double strand breaks

6 July 2018

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Crucial role of the amino-terminal tyrosine residue 42 and the carboxyl-terminal PEST domain of I kappa B alpha in NF-kappa B activation by an oxidative stress

6 July 2018

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Substrate specificities and identification of putative substrates of ATM kinase family members

6 July 2018

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ATM associates with and phosphorylates p53: mapping the region of interaction

6 July 2018

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Activation of the ATM kinase by ionizing radiation and phosphorylation of p53

6 July 2018

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Phosphorylation of NF-kappa B p65 by PKA stimulates transcriptional activity by promoting a novel bivalent interaction with the coactivator CBP/p300

6 July 2018

1 reference

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Highly-expressed p100/p52 (NFKB2) sequesters other NF-kappa B-related proteins in the cytoplasm of human breast cancer cells

6 July 2018

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Pseudotype formation of murine leukemia virus with the G protein of vesicular stomatitis virus

6 July 2018

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The ATM-mediated DNA-damage response: taking shape.

6 July 2018

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A cytoplasmic ATM-TRAF6-cIAP1 module links nuclear DNA damage signaling to ubiquitin-mediated NF-κB activation.

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0038246

The ATM protein is required for sustained activation of NF-kappaB following DNA damage.

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0038246

NF-kappaB activation by combinations of NEMO SUMOylation and ATM activation stresses in the absence of DNA damage.

21 January 2018

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HDAC inhibition prevents NF-kappa B activation by suppressing proteasome activity: down-regulation of proteasome subunit expression stabilizes I kappa B alpha

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0038246

Histone deacetylase inhibition down-regulates cyclin D1 transcription by inhibiting nuclear factor-kappaB/p65 DNA binding

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0038246

p53- and Mdm2-Independent Repression of NF-κB Transactivation by the ARF Tumor Suppressor

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0038246

IKKα limits macrophage NF-κB activation and contributes to the resolution of inflammation

21 January 2018

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Histone deacetylase inhibitor trichostatin A sustains sodium pervanadate-induced NF-kappaB activation by delaying IkappaBalpha mRNA resynthesis: comparison with tumor necrosis factor alpha

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22715377

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0038246

1 reference

1 August 2017

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1 August 2017

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