The tetraspanin CD37 orchestrates the α(4)β(1) integrin-Akt signaling axis and supports long-lived plasma cell survival (Q34311595)

1 August 2017

title

The tetraspanin CD37 orchestrates the α(4)β(1) integrin-Akt signaling axis and supports long-lived plasma cell survival (English)

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1 August 2017

Malou Zuidscherwoude

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Kate H Gartlan

Kate H Gartlan

4

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Alessandra Cambi

Alessandra Cambi

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Fabienne Mackay

Fabienne Mackay

12

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David M Tarlinton

David M Tarlinton

13

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Carl Figdor

Carl G Figdor

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author name string

Annemiek B van Spriel

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1 August 2017

Sandra de Keijzer

2

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Alie van der Schaaf

3

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1 August 2017

Mariam Sofi

5

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Amanda Light

6

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1 August 2017

Peter C Linssen

7

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Jan B Boezeman

8

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1 August 2017

Inge Reinieren-Beeren

10

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Mark D Wright

15

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language of work or name

English

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publication date

13 November 2012

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1 August 2017

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1 August 2017

volume

5

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1 August 2017

issue

250

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1 August 2017

page(s)

ra82

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Akt signaling: linking membrane events to life and death decisions

1 August 2017

cites work

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In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl)acetyl. I. The architecture and dynamics of responding cell populations

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B-cell activation by membrane-bound antigens is facilitated by the interaction of VLA-4 with VCAM-1

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Neonatally induced inactivation of the vascular cell adhesion molecule 1 gene impairs B cell localization and T cell-dependent humoral immune response

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Organization of the integrin LFA-1 in nanoclusters regulates its activity

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Functional insights on the polarized redistribution of leukocyte integrins and their ligands during leukocyte migration and immune interactions

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Characterization of integrin-tetraspanin adhesion complexes: role of tetraspanins in integrin signaling

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The tetraspanin web modulates immune-signalling complexes

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Tetraspanin functions and associated microdomains

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Lateral organization of membrane proteins: tetraspanins spin their web.

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Tetraspanins: push and pull in suppressing and promoting metastasis

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The tetraspanin protein CD37 regulates IgA responses and anti-fungal immunity

21 January 2018

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Targeted inactivation of the tetraspanin CD37 impairs T-cell-dependent B-cell response under suboptimal costimulatory conditions

21 January 2018

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A regulatory role for CD37 in T cell proliferation

21 January 2018

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Dectin-1 interaction with tetraspanin CD37 inhibits IL-6 production

21 January 2018

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Tetraspanins CD37 and CD151 differentially regulate Ag presentation and T-cell co-stimulation by DC.

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The tetraspanin CD37 protects against glomerular IgA deposition and renal pathology

21 January 2018

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AKT/PKB signaling: navigating downstream

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Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

21 January 2018

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Control of inflammation, cytokine expression, and germinal center formation by BCL-6

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Mcl-1 is essential for germinal center formation and B cell memory

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Follicular helper T cells as cognate regulators of B cell immunity

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T cells and follicular dendritic cells in germinal center B-cell formation and selection.

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The extent of affinity maturation differs between the memory and antibody-forming cell compartments in the primary immune response

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alpha 4 integrins mediate lymphocyte attachment and rolling under physiologic flow

21 January 2018

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Alpha4 integrins and the immune response

21 January 2018

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The CD81 tetraspanin facilitates instantaneous leukocyte VLA-4 adhesion strengthening to vascular cell adhesion molecule 1 (VCAM-1) under shear flow.

21 January 2018

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CD81 is essential for the re-entry of hematopoietic stem cells to quiescence following stress-induced proliferation via deactivation of the Akt pathway

21 January 2018

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A novel Fc-engineered monoclonal antibody to CD37 with enhanced ADCC and high proapoptotic activity for treatment of B-cell malignancies

21 January 2018

1 reference

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Tetraspanin CD37 directly mediates transduction of survival and apoptotic signals

21 January 2018

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Signaling through the tetraspanin CD82 triggers its association with the cytoskeleton leading to sustained morphological changes and T cell activation.

21 January 2018

1 reference

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EWI-2 and EWI-F link the tetraspanin web to the actin cytoskeleton through their direct association with ezrin-radixin-moesin proteins

21 January 2018

1 reference

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Binding of paxillin to alpha4 integrins modifies integrin-dependent biological responses

21 January 2018

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Paxillin selectively associates with constitutive and chemoattractant-induced high-affinity alpha4beta1 integrins: implications for integrin signaling.

21 January 2018

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Alpha4beta1-dependent adhesion strengthening under mechanical strain is regulated by paxillin association with the alpha4-cytoplasmic domain

21 January 2018

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CD45 links the B cell receptor with cell survival and is required for the persistence of germinal centers

21 January 2018

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21 January 2018

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21 January 2018

Identifiers

DOI

1 reference

1 August 2017

1 reference