Paradoxical lower serum triglyceride levels and higher type 2 diabetes mellitus susceptibility in obese individuals with the PNPLA3 148M variant (Q34314416)

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English	Paradoxical lower serum triglyceride levels and higher type 2 diabetes mellitus susceptibility in obese individuals with the PNPLA3 148M variant	scientific article

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scholarly article

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Europe PubMed Central

1 August 2017

Paradoxical lower serum triglyceride levels and higher type 2 diabetes mellitus susceptibility in obese individuals with the PNPLA3 148M variant (English)

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Europe PubMed Central

1 August 2017

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type 2 diabetes

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based on heuristic

inferred from title

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based on heuristic

inferred from title

14

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Tim Frayling

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Europe PubMed Central

1 August 2017

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Peter Jacobson

18

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Per-Arne Svensson

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Per-Arne Svensson

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Alexander S Doney

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Alexander S Doney

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Helen M. Colhoun

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Helen Colhoun

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Stefano Romeo

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Markku Peltonen

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Markku Peltonen

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John F Dillon

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Ewan R Pearson

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Mark McCarthy

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Andrew Tym Hattersley

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Andrew T Hattersley

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Europe PubMed Central

1 August 2017

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object named as

Jan Borén

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Europe PubMed Central

1 August 2017

Andrew D Morris

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object named as

Andrew D Morris

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Europe PubMed Central

1 August 2017

author name string

Colin N A Palmer

1

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Europe PubMed Central

1 August 2017

Cristina Maglio

2

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Europe PubMed Central

1 August 2017

Carlo Pirazzi

3

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Europe PubMed Central

1 August 2017

Maria Antonella Burza

4

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Europe PubMed Central

1 August 2017

Martin Adiels

5

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Europe PubMed Central

1 August 2017

Lindsay Burch

6

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Europe PubMed Central

1 August 2017

Louise A Donnelly

7

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Europe PubMed Central

1 August 2017

Lars Sjöström

20

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Europe PubMed Central

1 August 2017

Lena M S Carlsson

21

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1 August 2017

language of work or name

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publication date

18 June 2012

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Europe PubMed Central

1 August 2017

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Europe PubMed Central

1 August 2017

7

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Europe PubMed Central

1 August 2017

6

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Europe PubMed Central

1 August 2017

e39362

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Europe PubMed Central

1 August 2017

copyright license

Creative Commons Attribution 4.0 International

18 June 2012

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April 2022 Public Data File from Crossref

copyright status

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The association of PNPLA3 variants with liver enzymes in childhood obesity is driven by the interaction with abdominal fat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3377675

6 July 2018

Mendelian randomization studies do not support a role for raised circulating triglyceride levels influencing type 2 diabetes, glucose levels, or insulin resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3377675

6 July 2018

Common variants near ATM are associated with glycemic response to metformin in type 2 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3377675

6 July 2018

Pnpla3/Adiponutrin deficiency in mice does not contribute to fatty liver disease or metabolic syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3377675

6 July 2018

Patatin-like phospholipase domain-containing 3 and the pathogenesis and progression of pediatric nonalcoholic fatty liver disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3377675

6 July 2018

Effects of PNPLA3 on liver fat and metabolic profile in Hispanic children and adolescents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3377675

6 July 2018

Patatin-like phospholipase domain-containing 3/adiponutrin deficiency in mice is not associated with fatty liver disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3377675

6 July 2018

PNPLA3 variants specifically confer increased risk for histologic nonalcoholic fatty liver disease but not metabolic disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3377675

6 July 2018

Combined effect of inflammatory gene polymorphisms and the risk of ischemic stroke in a prospective cohort of subjects with type 2 diabetes: a Go-DARTS study.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3377675

6 July 2018

Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3377675

6 July 2018

A feed-forward loop amplifies nutritional regulation of PNPLA3

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3377675

6 July 2018

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3377675

6 July 2018

A sequence variation (I148M) in PNPLA3 associated with nonalcoholic fatty liver disease disrupts triglyceride hydrolysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3377675

6 July 2018

Genetic evidence for a role of adiponutrin in the metabolism of apolipoprotein B-containing lipoproteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3377675

6 July 2018

Dissociation between fatty liver and insulin resistance in humans carrying a variant of the patatin-like phospholipase 3 gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3377675

6 July 2018

Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3377675

6 July 2018

Overproduction of very low-density lipoproteins is the hallmark of the dyslipidemia in the metabolic syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3377675

6 July 2018

Contribution of de novo fatty acid synthesis to hepatic steatosis and insulin resistance: lessons from genetically engineered mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3377675

6 July 2018

The GCKR rs780094 polymorphism is associated with elevated fasting serum triacylglycerol, reduced fasting and OGTT-related insulinaemia, and reduced risk of type 2 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3377675

6 July 2018

Effects of Bariatric Surgery on Mortality in Swedish Obese Subjects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3377675

6 July 2018

Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3377675

6 July 2018

Disordered fat storage and mobilization in the pathogenesis of insulin resistance and type 2 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3377675

6 July 2018

Homeostasis model assessment: insulin resistance and ?-cell function from fasting plasma glucose and insulin concentrations in man

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3377675

6 July 2018

Introduction to the plasma lipoproteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3377675

6 July 2018

Tissue specificity of insulin resistance in humans: fat in the liver rather than muscle is associated with features of the metabolic syndrome

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0039362

21 January 2018

Increased liver fat, impaired insulin clearance, and hepatic and adipose tissue insulin resistance in type 2 diabetes

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0039362

21 January 2018

A common variant in PNPLA3, which encodes adiponutrin, is associated with liver fat content in humans

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0039362

21 January 2018

I148M patatin-like phospholipase domain-containing 3 gene variant and severity of pediatric nonalcoholic fatty liver disease

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0039362

21 January 2018

Morbid obesity exposes the association between PNPLA3 I148M (rs738409) and indices of hepatic injury in individuals of European descent

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0039362

21 January 2018

Mouse patatin-like phospholipase domain-containing 3 influences systemic lipid and glucose homeostasis

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0039362

21 January 2018

The 148M allele of the PNPLA3 gene is associated with indices of liver damage early in life.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0039362

21 January 2018

Increased cardiovascular morbidity and mortality in type 2 diabetes is associated with the glutathione S transferase theta-null genotype: a Go-DARTS study

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0039362

21 January 2018

The PNPLA3 I148M polymorphism is associated with insulin resistance and nonalcoholic fatty liver disease in a normoglycaemic population.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0039362

21 January 2018

The common adiponutrin variant p.I148M does not confer gallstone risk but affects fasting glucose and triglyceride levels.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3377675

28 October 2018

Swedish obese subjects (SOS). Recruitment for an intervention study and a selected description of the obese state

1 reference

https://pubmed.ncbi.nlm.nih.gov/22724004

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acute suppression of VLDL1 secretion rate by insulin is associated with hepatic fat content and insulin resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/22724004

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0039362

1 reference

Europe PubMed Central

1 August 2017

2012PLoSO...739362P

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1 reference

Europe PubMed Central

1 August 2017

1 reference

Europe PubMed Central

1 August 2017

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