Pnpla3/Adiponutrin deficiency in mice does not contribute to fatty liver disease or metabolic syndrome (Q34503398)

2 August 2017

Pnpla3/Adiponutrin deficiency in mice does not contribute to fatty liver disease or metabolic syndrome (English)

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2 August 2017

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Gabriele Schoiswohl

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Rudolf Zechner

object named as

Rudolf Zechner

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author name string

Mahesh K Basantani

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2 August 2017

Mitch T Sitnick

2

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2 August 2017

Lingzhi Cai

3

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2 August 2017

Daniel S Brenner

4

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2 August 2017

Noah P Gardner

5

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2 August 2017

John Zhong Li

6

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2 August 2017

Kui Yang

8

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2 August 2017

Manju Kumari

9

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2 August 2017

Richard W Gross

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2 August 2017

Erin E Kershaw

12

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2 August 2017

9 November 2010

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Journal of Lipid Research

2 August 2017

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2 August 2017

52

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2 August 2017

2

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2 August 2017

318-329

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The association of genetic variability in patatin-like phospholipase domain-containing protein 3 (PNPLA3) with histological severity of nonalcoholic fatty liver disease

2 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023552

Patatin-like phospholipase domain-containing 3/adiponutrin deficiency in mice is not associated with fatty liver disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023552

PNPLA3 variants specifically confer increased risk for histologic nonalcoholic fatty liver disease but not metabolic disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023552

A feed-forward loop amplifies nutritional regulation of PNPLA3

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023552

The role of fructose in the pathogenesis of NAFLD and the metabolic syndrome

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023552

A sequence variation (I148M) in PNPLA3 associated with nonalcoholic fatty liver disease disrupts triglyceride hydrolysis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023552

A nonsynonymous gene variant in the adiponutrin gene is associated with nonalcoholic fatty liver disease severity.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023552

Genetic evidence for a role of adiponutrin in the metabolism of apolipoprotein B-containing lipoproteins

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023552

Adipose triglyceride lipase deficiency causes tissue-specific changes in insulin signaling

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023552

Dissociation between fatty liver and insulin resistance in humans carrying a variant of the patatin-like phospholipase 3 gene

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023552

A common variant in the adiponutrin gene influences liver enzyme values

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023552

Automated lipid identification and quantification by multidimensional mass spectrometry-based shotgun lipidomics

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023552

Genetic variance in the adiponutrin gene family and childhood obesity.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023552

The MIQE guidelines: minimum information for publication of quantitative real-time PCR experiments

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023552

Mammalian patatin domain containing proteins: a family with diverse lipolytic activities involved in multiple biological functions

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023552

7 July 2018

The metabolic syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023552

Population-based genome-wide association studies reveal six loci influencing plasma levels of liver enzymes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023552

Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023552

Causes and metabolic consequences of Fatty liver

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023552

Dietary lipoic acid-dependent changes in the activity and mRNA levels of hepatic lipogenic enzymes in rats

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023552

Fatty liver: a novel component of the metabolic syndrome

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023552

A comparative study of human GS2, its paralogues, and its rat orthologue

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023552

Adipose triglyceride lipase and hormone-sensitive lipase are the major enzymes in adipose tissue triacylglycerol catabolism

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023552

Characterization of the human patatin-like phospholipase family

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023552

Adipose triglyceride lipase: function, regulation by insulin, and comparison with adiponutrin

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023552

Expression, regulation, and triglyceride hydrolase activity of Adiponutrin family members.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023552

Adipocyte-specific glucocorticoid inactivation protects against diet-induced obesity

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023552

Prevalence of hepatic steatosis in an urban population in the United States: impact of ethnicity

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023552

Fat mobilization in adipose tissue is promoted by adipose triglyceride lipase

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023552

Identification, cloning, expression, and purification of three novel human calcium-independent phospholipase A2 family members possessing triacylglycerol lipase and acylglycerol transacylase activities

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023552

Adiponutrin: A new gene regulated by energy balance in human adipose tissue

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023552

A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023552

A simple method for the isolation and purification of total lipides from animal tissues

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023552

Minireview: weapons of lean body mass destruction: the role of ectopic lipids in the metabolic syndrome

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023552

Adiponutrin gene expression in 3T3-L1 adipocytes is downregulated by troglitazone

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023552

Lipotoxicity: when tissues overeat

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023552

A highly efficient recombineering-based method for generating conditional knockout mutations

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023552

Nonalcoholic fatty liver disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023552

Hormone-sensitive lipase deficiency in mice causes diglyceride accumulation in adipose tissue, muscle, and testis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023552

Adiponutrin, a transmembrane protein corresponding to a novel dietary- and obesity-linked mRNA specifically expressed in the adipose lineage

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023552

A highly efficient Escherichia coli-based chromosome engineering system adapted for recombinogenic targeting and subcloning of BAC DNA

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023552

Role of LXRs in control of lipogenesis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023552

Overproduction of cholesterol and fatty acids causes massive liver enlargement in transgenic mice expressing truncated SREBP-1a

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023552

A common variant in PNPLA3, which encodes adiponutrin, is associated with liver fat content in humans

7 July 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M011205

A single nucleotide polymorphism (SNP) rs2072907 in the adiponutrin gene (ADPN) was not associated with obesity and type 2 diabetes in Chinese population

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M011205

Morbid obesity exposes the association between PNPLA3 I148M (rs738409) and indices of hepatic injury in individuals of European descent

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M011205

Homozygosity for the patatin-like phospholipase-3/adiponutrin I148M polymorphism influences liver fibrosis in patients with nonalcoholic fatty liver disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M011205

The 148M allele of the PNPLA3 gene is associated with indices of liver damage early in life.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M011205

I148M patatin-like phospholipase domain-containing 3 gene variant and severity of pediatric nonalcoholic fatty liver disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M011205

Variation in the adiponutrin gene influences its expression and associates with obesity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M011205

Polymorphisms in the adiponutrin gene are associated with increased insulin secretion and obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M011205

Regulation of adiponutrin expression by feeding conditions in rats is altered in the obese state.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M011205

Adiponutrin mRNA expression in white adipose tissue is rapidly induced by meal-feeding a high-sucrose diet

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M011205

Food restriction regulates adipose-specific cytokines in pituitary gland but not in hypothalamus

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M011205

Macronutrient composition of the diet differentially affects leptin and adiponutrin mRNA expression in response to meal feeding

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M011205

Differences in mRNA expression of adipocyte-derived factors in response to fasting, refeeding and leptin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M011205

The expression level of non-alcoholic fatty liver disease-related gene PNPLA3 in hepatocytes is highly influenced by hepatic lipid status.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M011205

Adiponutrin gene is regulated by insulin and glucose in human adipose tissue.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M011205

Tri-iodothyronine upregulates adiponutrin mRNA expression in rat and human adipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M011205

Stimulation of cholesterol excretion by the liver X receptor agonist requires ATP-binding cassette transporters G5 and G8.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M011205

Quantitative analysis and molecular species fingerprinting of triacylglyceride molecular species directly from lipid extracts of biological samples by electrospray ionization tandem mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M011205

Nonalcoholic fatty liver disease: a feature of the metabolic syndrome

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3023552

Regulation of absorption and ABC1-mediated efflux of cholesterol by RXR heterodimers

27 October 2018

1 reference

12 December 2020

Optimisation of oil red O staining permits combination with immunofluorescence and automated quantification of lipids

1 reference

12 December 2020

34 Measurement of rates of lipogenesis with deuterated and tritiated water

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12 December 2020

Measurement of rates of cholesterol synthesis using tritiated water

1 reference

12 December 2020

Insulin regulation of gene expression and concentrations of white adipose tissue-derived proteins in vivo in healthy men: relation to adiponutrin

1 reference

12 December 2020

Identifiers

DOI

10.1194/JLR.M011205

1 reference

2 August 2017

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2 August 2017

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