FGF21 acts centrally to induce sympathetic nerve activity, energy expenditure, and weight loss. (Q34315567)

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12 March 2020

title

FGF21 acts centrally to induce sympathetic nerve activity, energy expenditure, and weight loss (English)

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12 March 2020

1

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12 March 2020

Katie Colbert Coate

4

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12 March 2020

Kamal Rahmouni

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David Mangelsdorf

8

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author name string

Xunshan Ding

2

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Donald A Morgan

3

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Angie L Bookout

5

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Steven A Kliewer

7

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publication date

14 August 2014

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12 March 2020

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volume

20

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issue

4

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page(s)

670-677

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Interplay between FGF21 and insulin action in the liver regulates metabolism

12 March 2020

cites work

1 reference

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FGF19 action in the brain induces insulin-independent glucose lowering

6 July 2018

1 reference

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The breadth of FGF21's metabolic actions are governed by FGFR1 in adipose tissue

6 July 2018

1 reference

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FGF21 regulates metabolism and circadian behavior by acting on the nervous system

6 July 2018

1 reference

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FGF21 contributes to neuroendocrine control of female reproduction

6 July 2018

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An FGF21-adiponectin-ceramide axis controls energy expenditure and insulin action in mice

6 July 2018

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βKlotho is required for fibroblast growth factor 21 effects on growth and metabolism

6 July 2018

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Direct control of brown adipose tissue thermogenesis by central nervous system glucagon-like peptide-1 receptor signaling

6 July 2018

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FGF21 promotes metabolic homeostasis via white adipose and leptin in mice

6 July 2018

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BMP8B increases brown adipose tissue thermogenesis through both central and peripheral actions

6 July 2018

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Liver LXRα expression is crucial for whole body cholesterol homeostasis and reverse cholesterol transport in mice

6 July 2018

1 reference

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FGF21 regulates PGC-1α and browning of white adipose tissues in adaptive thermogenesis

6 July 2018

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Endocrine fibroblast growth factors 15/19 and 21: from feast to famine

6 July 2018

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Amelioration of type 2 diabetes by antibody-mediated activation of fibroblast growth factor receptor 1.

6 July 2018

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Fibroblast growth factor 21 (FGF21) in human cerebrospinal fluid: relationship with plasma FGF21 and body adiposity

6 July 2018

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Ablation of the leptin receptor in the hypothalamic arcuate nucleus abrogates leptin-induced sympathetic activation

6 July 2018

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Research resource: Comprehensive expression atlas of the fibroblast growth factor system in adult mouse.

6 July 2018

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Differential effects of insulin on sympathetic nerve activity in agouti obese mice

6 July 2018

1 reference

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Fibroblast growth factor 21 action in the brain increases energy expenditure and insulin sensitivity in obese rats

6 July 2018

1 reference

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Hepatic FGF21 expression is induced at birth via PPARalpha in response to milk intake and contributes to thermogenic activation of neonatal brown fat.

6 July 2018

1 reference

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Vasopressin and the output of the hypothalamic biological clock.

6 July 2018

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Acute glucose-lowering and insulin-sensitizing action of FGF21 in insulin-resistant mouse models--association with liver and adipose tissue effects

6 July 2018

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Fibroblast growth factor 21 corrects obesity in mice

6 July 2018

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Inhibition of growth hormone signaling by the fasting-induced hormone FGF21.

6 July 2018

1 reference

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FGFR2-amplified gastric cancer cell lines require FGFR2 and Erbb3 signaling for growth and survival

6 July 2018

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The fasting polypeptide FGF21 can enter brain from blood

6 July 2018

1 reference

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The metabolic state of diabetic monkeys is regulated by fibroblast growth factor-21.

6 July 2018

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Corticotropin releasing factor increases in brown adipose tissue thermogenesis and heart rate through dorsomedial hypothalamus and medullary raphe pallidus.

6 July 2018

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PPARgamma in the control of brown adipocyte differentiation.

6 July 2018

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FGF-21 as a novel metabolic regulator

6 July 2018

1 reference

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Peroxisome proliferator-activated receptor gamma agonism increases the capacity for sympathetically mediated thermogenesis in lean and ob/ob mice.

6 July 2018

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Brown adipose tissue: function and physiological significance

6 July 2018

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Crystal structure of an angiogenesis inhibitor bound to the FGF receptor tyrosine kinase domain.

6 July 2018

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Effects of corticotropin-releasing factor on food intake and brown adipose tissue thermogenesis in rats

6 July 2018

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The effects of LY2405319, an FGF21 analog, in obese human subjects with type 2 diabetes

6 July 2018

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Adiponectin mediates the metabolic effects of FGF21 on glucose homeostasis and insulin sensitivity in mice

28 October 2018

1 reference

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Long-acting FGF21 has enhanced efficacy in diet-induced obese mice and in obese rhesus monkeys

28 October 2018

1 reference

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Fibroblast growth factor 21 reverses hepatic steatosis, increases energy expenditure, and improves insulin sensitivity in diet-induced obese mice

28 October 2018

1 reference

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Induction of uncoupling protein in brown adipose tissue. Synergy between norepinephrine and pioglitazone, an insulin-sensitizing agent

28 October 2018

1 reference

12 December 2020

Activation of brown fat thermogenesis in response to central injection of corticotropin releasing hormone in the rat

1 reference

12 December 2020

High-throughput real-time quantitative reverse transcription PCR

1 reference

12 December 2020

Stress-induced inhibition of reproductive functions: role of endogenous corticotropin-releasing factor

1 reference

12 December 2020

Ciglitazone is not itself thermogenic but increases the potential for thermogenesis in lean mice

1 reference

12 December 2020

Role of corticotrophin-releasing factor in effects of leptin on sympathetic nerve activity and arterial pressure

1 reference

12 December 2020

10.1016/J.CMET.2014.07.012

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25130400%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

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12 March 2020

PubMed publication ID

25130400

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25130400%20AND%20SRC:MED&resulttype=core&format=json