FGF21 regulates PGC-1α and browning of white adipose tissues in adaptive thermogenesis (Q35755169)

10 August 2017

FGF21 regulates PGC-1α and browning of white adipose tissues in adaptive thermogenesis (English)

1 reference

Fibroblast growth factor 21

10 August 2017

1 reference

positive regulation of cold-induced thermogenesis

GOA release 2020-03-11

1 reference

Fibroblast growth factor 21

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

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Bruce M Spiegelman

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10 August 2017

Eleftheria Maratos-Flier

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object named as

Eleftheria Maratos-Flier

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Jeffrey S Flier

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Alexei Kharitonenkov

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10 August 2017

Ffolliott M Fisher

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Sandra Kleiner

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Nicholas Douris

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10 August 2017

Elliott C Fox

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Rina J Mepani

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10 August 2017

Francisco Verdeguer

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10 August 2017

Jun Wu

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10 August 2017

language of work or name

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1 February 2012

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271-281

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describes a project that uses

10 August 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3278894/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Integrated regulation of hepatic metabolism by fibroblast growth factor 21 (FGF21) in vivo

1 reference

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Brown adipose tissue responds to cold and adrenergic stimulation by induction of FGF21.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3278894

Thermogenic activation induces FGF21 expression and release in brown adipose tissue.

2 October 2017

1 reference

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Nonshivering thermogenesis and its adequate measurement in metabolic studies

2 October 2017

1 reference

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Prdm16 determines the thermogenic program of subcutaneous white adipose tissue in mice

2 October 2017

1 reference

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Obesity is a fibroblast growth factor 21 (FGF21)-resistant state

2 October 2017

1 reference

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Inducible lineage tracing of Pax7-descendant cells reveals embryonic origin of adult satellite cells

2 October 2017

1 reference

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Hepatic FGF21 expression is induced at birth via PPARalpha in response to milk intake and contributes to thermogenic activation of neonatal brown fat.

2 October 2017

1 reference

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Chronic peroxisome proliferator-activated receptor gamma (PPARgamma) activation of epididymally derived white adipocyte cultures reveals a population of thermogenically competent, UCP1-containing adipocytes molecularly distinct from classic [...]

2 October 2017

1 reference

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Deletion of tumor necrosis factor-alpha receptor 1 (TNFR1) protects against diet-induced obesity by means of increased thermogenesis

2 October 2017

1 reference

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Fibroblast growth factor 21-deficient mice demonstrate impaired adaptation to ketosis

2 October 2017

1 reference

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Inhibition of lipolysis may contribute to the acute regulation of plasma FFA and glucose by FGF21 in ob/ob mice

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3278894

FGF21 induces PGC-1alpha and regulates carbohydrate and fatty acid metabolism during the adaptive starvation response

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3278894

Fibroblast growth factor 21 controls glycemia via regulation of hepatic glucose flux and insulin sensitivity

2 October 2017

1 reference

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UCP1 ablation induces obesity and abolishes diet-induced thermogenesis in mice exempt from thermal stress by living at thermoneutrality

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3278894

PRDM16 controls a brown fat/skeletal muscle switch

2 October 2017

1 reference

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Fibroblast growth factor 21 corrects obesity in mice

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3278894

Liver X receptor alpha is a transcriptional repressor of the uncoupling protein 1 gene and the brown fat phenotype.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3278894

Hepatic fibroblast growth factor 21 is regulated by PPARalpha and is a key mediator of hepatic lipid metabolism in ketotic states

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3278894

Endocrine regulation of the fasting response by PPARalpha-mediated induction of fibroblast growth factor 21

2 October 2017

1 reference

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Fibroblast growth factor-21 improves pancreatic beta-cell function and survival by activation of extracellular signal-regulated kinase 1/2 and Akt signaling pathways.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3278894

FGF-21 as a novel metabolic regulator

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3278894

Retinoblastoma protein functions as a molecular switch determining white versus brown adipocyte differentiation.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3278894

FOXC2 is a winged helix gene that counteracts obesity, hypertriglyceridemia, and diet-induced insulin resistance

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3278894

Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3278894

Expression of the mitochondrial uncoupling protein gene from the aP2 gene promoter prevents genetic obesity

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3278894

Development of obesity in transgenic mice after genetic ablation of brown adipose tissue

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3278894

FGF21 attenuates lipolysis in human adipocytes - a possible link to improved insulin sensitivity

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3278894

Molecular determinants of FGF-21 activity-synergy and cross-talk with PPARgamma signaling

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3278894

RIP140-targeted repression of gene expression in adipocytes

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3278894

Adipose tissue reduction in mice lacking the translational inhibitor 4E-BP1.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3278894

Occurrence of brown adipocytes in rat white adipose tissue: molecular and morphological characterization

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3278894

The emergence of cold-induced brown adipocytes in mouse white fat depots is determined predominantly by white to brown adipocyte transdifferentiation.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3278894

Fibroblast growth factor 21 reduces the severity of cerulein-induced pancreatitis in mice

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3278894

Fibroblast growth factor 21 reverses hepatic steatosis, increases energy expenditure, and improves insulin sensitivity in diet-induced obese mice

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3278894

Peroxisome proliferator-activated receptor alpha activates transcription of the brown fat uncoupling protein-1 gene. A link between regulation of the thermogenic and lipid oxidation pathways in the brown fat cell.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3278894

Appearance of brown adipocytes in white adipose tissue during CL 316,243-induced reversal of obesity and diabetes in Zucker fa/fa rats

25 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22302939

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Reversible physiological transdifferentiation in the adipose organ

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22302939

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1101/GAD.177857.111

1 reference

10 August 2017

1 reference

10 August 2017

1 reference