Phosphorylation of Ser312 contributes to tumor suppression by p53 in vivo (Q34320401)

1 August 2017

title

Phosphorylation of Ser312 contributes to tumor suppression by p53 in vivo (English)

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1 August 2017

1 reference

Elizabeth A Slee

1

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1 August 2017

Barbara Benassi

2

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1 August 2017

Robert Goldin

3

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1 August 2017

Shan Zhong

4

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1 August 2017

Indrika Ratnayaka

5

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1 August 2017

Giovanni Blandino

6

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1 August 2017

Xin Lu

7

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1 August 2017

language of work or name

English

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publication date

20 October 2010

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1 August 2017

number of pages

6

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Proceedings of the National Academy of Sciences of the United States of America

inferred from page(s)

published in

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1 August 2017

volume

107

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1 August 2017

issue

45

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1 August 2017

page(s)

19479-19484

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A complex barcode underlies the heterogeneous response of p53 to stress

1 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984175

Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984175

Regulating the p53 pathway: in vitro hypotheses, in vivo veritas

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984175

Ser18 and 23 phosphorylation is required for p53-dependent apoptosis and tumor suppression

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984175

Increased sensitivity to UV radiation in mice with a p53 point mutation at Ser389.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984175

Defective apoptosis and B-cell lymphomas in mice with p53 point mutation at Ser 23.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984175

Endoplasmic reticulum stress induces p53 cytoplasmic localization and prevents p53-dependent apoptosis by a pathway involving glycogen synthase kinase-3beta

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984175

Absence of p21 partially rescues Mdm4 loss and uncovers an antiproliferative effect of Mdm4 on cell growth

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984175

Activation of the DNA-binding ability of latent p53 protein by protein kinase C is abolished by protein kinase CK2.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984175

Tissue-specific induction of p53 targets in vivo.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984175

The prolyl isomerase Pin1 reveals a mechanism to control p53 functions after genotoxic insults

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984175

Mdm4 (Mdmx) regulates p53-induced growth arrest and neuronal cell death during early embryonic mouse development

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984175

Rescue of embryonic lethality in Mdm4-null mice by loss of Trp53 suggests a nonoverlapping pathway with MDM2 to regulate p53

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984175

Development of spontaneous mammary tumors in BALB/c p53 heterozygous mice. A model for Li-Fraumeni syndrome

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984175

Stoichiometric phosphorylation of human p53 at Ser315 stimulates p53-dependent transcription

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984175

Reduced p21(WAF1/CIP1) protein expression is predominantly related to altered p53 in hepatocellular carcinomas

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984175

The p53 response to ionising radiation in adult and developing murine tissues.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984175

p53 is required for radiation-induced apoptosis in mouse thymocytes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984175

Tumor spectrum analysis in p53-mutant mice

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984175

Increased and altered DNA binding of human p53 by S and G2/M but not Gl cyclin-dependent kinases

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984175

Human p53 is phosphorylated by p60-cdc2 and cyclin B-cdc2

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984175

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984175

Proto-oncogene activation in liver tumors of hepatocarcinogenesis-resistant strains of mice

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984175

Phosphorylation by aurora kinase A induces Mdm2-mediated destabilization and inhibition of p53.

6 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1005165107

Cell cycle-dependent nuclear retention of p53 by E2F1 requires phosphorylation of p53 at Ser315.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1005165107

The prolyl isomerase Pin1 is a regulator of p53 in genotoxic response.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1005165107

Thymocyte apoptosis induced by p53-dependent and independent pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1005165107

Lack of p53 Ser389 phosphorylation predisposes mice to develop 2-acetylaminofluorene-induced bladder tumors but not ionizing radiation-induced lymphomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1005165107

Changes in transcriptome after in vivo exposure to ionising radiation reveal a highly specialised liver response

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1005165107

Tumor susceptibility of p21(Waf1/Cip1)-deficient mice.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2984175

mdmx is a negative regulator of p53 activity in vivo

28 October 2018

1 reference

12 December 2020

Chromosome stability, in the absence of apoptosis, is critical for suppression of tumorigenesis in Trp53 mutant mice

1 reference

12 December 2020

Genetic background alters the spectrum of tumors that develop in p53-deficient mice

1 reference

12 December 2020

p53-deficient mice are extremely susceptible to radiation-induced tumorigenesis

1 reference

12 December 2020

p53 Deficiency in liver reduces local control of survival and proliferation, but does not affect apoptosis after DNA damage

1 reference

12 December 2020

Mutant p53 gain of function in two mouse models of Li-Fraumeni syndrome

1 reference

12 December 2020

CDK9 phosphorylates p53 on serine residues 33, 315 and 392

1 reference

12 December 2020

Spontaneous lesions in aging FVB/N mice

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.1005165107

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1 August 2017

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1 August 2017

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