Therapeutic opportunities from muscarinic receptor research (Q34322725)

1 August 2017

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title

Therapeutic opportunities from muscarinic receptor research (English)

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1 August 2017

Eglen RM

1

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PubMed ID

11479003

1 August 2017

Choppin A

series ordinal

2

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PubMed ID

11479003

1 August 2017

Watson N

series ordinal

3

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1 August 2017

1 August 2001

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Trends in Pharmacological Sciences

1 August 2017

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1 August 2017

22

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1 August 2017

8

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1 August 2017

409-414

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Muscarinic-induced modulation of potassium conductances is unchanged in mouse hippocampal pyramidal cells that lack functional M1 receptors

1 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901737-5

7 January 2021

Pronounced pharmacologic deficits in M2 muscarinic acetylcholine receptor knockout mice

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901737-5

7 January 2021

Multiple functional defects in peripheral autonomic organs in mice lacking muscarinic acetylcholine receptor gene for the M3 subtype

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901737-5

7 January 2021

Enhancement of D1 dopamine receptor-mediated locomotor stimulation in M(4) muscarinic acetylcholine receptor knockout mice

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901737-5

7 January 2021

G protein-coupled receptors: functional and mechanistic insights through altered gene expression

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901737-5

7 January 2021

Muscarinic toxins from the green mamba

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901737-5

7 January 2021

Selective muscarinic receptor agonists and antagonists

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901737-5

7 January 2021

Pirenzepine. A review of its pharmacodynamic and pharmacokinetic properties and therapeutic efficacy in peptic ulcer disease and other allied diseases

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901737-5

7 January 2021

Tolterodine, a new antimuscarinic agent: as effective but better tolerated than oxybutynin in patients with an overactive bladder

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901737-5

7 January 2021

Muscarinic agonists for the treatment of Alzheimer's disease: progress and perspectives.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901737-5

7 January 2021

Therapeutic opportunities for muscarinic receptors in the central nervous system

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901737-5

7 January 2021

Differential regulation of molecular subtypes of muscarinic receptors in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901737-5

7 January 2021

Pharmacological basis for functional selectivity of partial muscarinic receptor agonists

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901737-5

7 January 2021

Release of Alzheimer amyloid precursor derivatives stimulated by activation of muscarinic acetylcholine receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901737-5

7 January 2021

Cholinergic agonists and interleukin 1 regulate processing and secretion of the Alzheimer beta/A4 amyloid protein precursor

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901737-5

7 January 2021

Cholinesterase inhibitors: A new class of psychotropic compounds

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901737-5

7 January 2021

Pirenzepine distinguishes between different subclasses of muscarinic receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901737-5

7 January 2021

Muscarinic acetylcholine receptor subtypes in smooth muscle

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901737-5

7 January 2021

Differential coupling of muscarinic m2 and m3 receptors to adenylyl cyclases V/VI in smooth muscle. Concurrent M2-mediated inhibition via Galphai3 and m3-mediated stimulation via Gbetagammaq

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901737-5

7 January 2021

Decreased adenylyl cyclase protein and function in airway smooth muscle by chronic carbachol pretreatment

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901737-5

7 January 2021

Muscarinic inhibition of single KCa channels in smooth muscle cells by a pertussis-sensitive G protein.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901737-5

7 January 2021

Muscarinic receptors controlling the carbachol-activated nonselective cationic current in guinea pig gastric smooth muscle cells

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901737-5

7 January 2021

Acetylcholine activates non-selective cation and chloride conductances in canine and guinea-pig tracheal myocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901737-5

7 January 2021

M2 receptor activation of nonselective cation channels in smooth muscle cells: calcium and Gi/G(o) requirements

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901737-5

7 January 2021

Characterization of the interaction between muscarinic M2 receptors and beta-adrenoceptor subtypes in guinea-pig isolated ileum

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901737-5

7 January 2021

Differential effects of pertussis toxin on muscarinic responses in isolated atria and smooth muscle

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901737-5

7 January 2021

Pertussis toxin augments beta-adrenergic relaxation of muscarinic contraction in canine trachealis

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901737-5

7 January 2021

Role of muscarinic M2 and M3 receptors in guinea-pig trachea: effects of receptor alkylation

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901737-5

7 January 2021

Tolterodine--a new bladder selective muscarinic receptor antagonist: preclinical pharmacological and clinical data

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901737-5

7 January 2021

Muscarinic receptor antagonists in the treatment of overactive bladder

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901737-5

7 January 2021

Oxybutynin. A review of its pharmacodynamic and pharmacokinetic properties, and its therapeutic use in detrusor instability.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901737-5

7 January 2021

Discovery & development of selective M3 antagonists for clinical use.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901737-5

7 January 2021

A randomised controlled comparison of tiotropium nd ipratropium in the treatment of chronic obstructive pulmonary disease. The Dutch Tiotropium Study Group

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901737-5

7 January 2021

The M5 (m5) receptor subtype: fact or fiction?

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901737-5

7 January 2021

The muscarinic M(5) receptor: a silent or emerging subtype?

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901737-5

7 January 2021

Pharmacology of muscarinic acetylcholine receptor subtypes (m1-m5): high throughput assays in mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901737-5

7 January 2021

Comparative pharmacology of recombinant human M3 and M5 muscarinic receptors expressed in CHO-K1 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901737-5

7 January 2021

Identification and localization of muscarinic acetylcholine receptor proteins in brain with subtype-specific antibodies

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901737-5

7 January 2021

Role of tegmental cholinergic neurons in dopaminergic activation, antimuscarinic psychosis and schizophrenia

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901737-5

7 January 2021

Radioligand binding assay of M1-M5 muscarinic cholinergic receptor subtypes in human peripheral blood lymphocytes.

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901737-5

7 January 2021

Muscarinic--but not nicotinic--acetylcholine receptors mediate a nitric oxide-dependent dilation in brain cortical arterioles: a possible role for the M5 receptor subtype

1 reference

https://api.crossref.org/works/10.1016%2FS0165-6147%2800%2901737-5

7 January 2021

10.1016/S0165-6147(00)01737-5

Identifiers

DOI

1 reference

1 August 2017

1 reference

PubMed ID

11479003