Putative tumor suppressor Lats2 induces apoptosis through downregulation of Bcl-2 and Bcl-x(L). (Q34334749)

1 August 2017

Putative tumor suppressor Lats2 induces apoptosis through downregulation of Bcl-2 and Bcl-x(L). (English)

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1 August 2017

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Hengning Ke

1

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1 August 2017

Jing Pei

2

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1 August 2017

Zhenya Ni

3

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1 August 2017

Hong Xia

4

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1 August 2017

Huilin Qi

5

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1 August 2017

Tishonna Woods

6

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1 August 2017

Ameeta Kelekar

7

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1 August 2017

Wufan Tao

8

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1 August 2017

language of work or name

English

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publication date

1 August 2004

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Experimental Cell Research

1 August 2017

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1 August 2017

298

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2

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1 August 2017

329-338

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The Drosophila tumor suppressor gene warts encodes a homolog of human myotonic dystrophy kinase and is required for the control of cell shape and proliferation

1 August 2017

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.04.031

Molecular cloning of a novel human protein kinase, kpm, that is homologous to warts/lats, a Drosophila tumor suppressor

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.04.031

Structure, expression, and chromosome mapping of LATS2, a mammalian homologue of the Drosophila tumor suppressor gene lats/warts

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.04.031

Human homologue of the Drosophila melanogaster lats tumour suppressor modulates CDC2 activity

7 January 2021

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A human homolog of Drosophila warts tumor suppressor, h-warts, localized to mitotic apparatus and specifically phosphorylated during mitosis

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.04.031

salvador Promotes both cell cycle exit and apoptosis in Drosophila and is mutated in human cancer cell lines

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.04.031

Mice deficient of Lats1 develop soft-tissue sarcomas, ovarian tumours and pituitary dysfunction

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.04.031

LATS1 tumor suppressor regulates G2/M transition and apoptosis

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.04.031

Human homologue of Drosophila lats, LATS1, negatively regulate growth by inducing G(2)/M arrest or apoptosis.

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.04.031

Lats2, a putative tumor suppressor, inhibits G1/S transition

7 January 2021

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Inhibition of cell growth by conditional expression of kpm, a human homologue of Drosophila warts/lats tumor suppressor

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.04.031

The Drosophila Mst ortholog, hippo, restricts growth and cell proliferation and promotes apoptosis

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.04.031

hippo encodes a Ste-20 family protein kinase that restricts cell proliferation and promotes apoptosis in conjunction with salvador and warts

7 January 2021

1 reference

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Efficient generation of recombinant adenoviruses using adenovirus DNA-terminal protein complex and a cosmid bearing the full-length virus genome

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Bcl-xL regulates apoptosis by heterodimerization-dependent and -independent mechanisms

7 January 2021

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Evaluation of caspase activity in apoptotic cells

7 January 2021

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Inhibition of human caspases by peptide-based and macromolecular inhibitors

7 January 2021

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Caspases are activated in a branched protease cascade and control distinct downstream processes in Fas-induced apoptosis

7 January 2021

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A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis

7 January 2021

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The Bcl2 family: regulators of the cellular life-or-death switch

7 January 2021

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Activity of a novel bcl-2/bcl-xL-bispecific antisense oligonucleotide against tumors of diverse histologic origins.

7 January 2021

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Down-regulation of Bcl-2 and Bcl-xL expression with bispecific antisense treatment in glioblastoma cell lines induce cell death.

7 January 2021

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Investigations of antisense oligonucleotides targeted against bcl-2 RNAs.

7 January 2021

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Induction of apoptosis in small-cell lung cancer cells by an antisense oligodeoxynucleotide targeting the Bcl-2 coding sequence

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.04.031

Mammalian caspases: structure, activation, substrates, and functions during apoptosis

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.04.031

Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.04.031

Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.04.031

Ordering the cytochrome c-initiated caspase cascade: hierarchical activation of caspases-2, -3, -6, -7, -8, and -10 in a caspase-9-dependent manner

7 January 2021

1 reference

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Inactivation of caspase-8 on mitochondria of Bcl-xL-expressing MCF7-Fas cells: role for the bifunctional apoptosis regulator protein

7 January 2021

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Unwinding the loop of Bcl-2 phosphorylation

7 January 2021

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Caspase-6 is the direct activator of caspase-8 in the cytochrome c-induced apoptosis pathway: absolute requirement for removal of caspase-6 prodomain

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.YEXCR.2004.04.031

p53-dependent apoptosis pathways.

7 January 2021

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p53 and apoptosis: it's not just in the nucleus anymore

7 January 2021

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10.1016/J.YEXCR.2004.04.031

7 January 2021

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DOI

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1 August 2017

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