Unwinding the loop of Bcl-2 phosphorylation (Q33952267)

30 July 2017

1 reference

title

Unwinding the loop of Bcl-2 phosphorylation (English)

1 reference

30 July 2017

1 reference

1

Blagosklonny MV

1 reference

30 July 2017

1 June 2001

1 reference

30 July 2017

1 reference

30 July 2017

15

1 reference

30 July 2017

869-874

1 reference

30 July 2017

6

1 reference

https://scigraph.springernature.com/pub.10.1038/sj.leu.2402134

30 July 2017

0 references

cites work

A day in the life of the Bcl-2 protein: does the turnover rate of Bcl-2 serve as a biological clock for cellular lifespan regulation?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402134

7 January 2021

Double identity for proteins of the Bcl-2 family

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402134

7 January 2021

BCL-2 family: regulators of cell death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402134

7 January 2021

Bcl-2 proteins: regulators of apoptosis or of mitochondrial homeostasis?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402134

7 January 2021

Inactivation of Bcl-2 by phosphorylation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402134

7 January 2021

BCL-2 is phosphorylated and inactivated by an ASK1/Jun N-terminal protein kinase pathway normally activated at G(2)/M.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402134

7 January 2021

Bcl-2 phosphorylation required for anti-apoptosis function

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402134

7 January 2021

Microtubules and actin filaments: dynamic targets for cancer chemotherapy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402134

7 January 2021

Screening of a library of phage-displayed peptides identifies human bcl-2 as a taxol-binding protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402134

7 January 2021

Mitotic phosphorylation of Bcl-2 during normal cell cycle progression and Taxol-induced growth arrest

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402134

7 January 2021

Phosphorylation of Bcl-2 is a marker of M phase events and not a determinant of apoptosis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402134

7 January 2021

Identification of a novel regulatory domain in Bcl-X(L) and Bcl-2.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402134

7 January 2021

Apoptosis: cell death defined by caspase activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402134

7 January 2021

Caspases and apoptosis – biology and terminology

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402134

7 January 2021

Cell death beyond apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402134

7 January 2021

More than one way to go.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402134

7 January 2021

Mitochondria and apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402134

7 January 2021

BCL-2 family members and the mitochondria in apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402134

7 January 2021

Temporal relationship of CDK1 activation and mitotic arrest to cytosolic accumulation of cytochrome C and caspase-3 activity during Taxol-induced apoptosis of human AML HL-60 cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402134

7 January 2021

The p53-binding protein 53BP2 also interacts with Bc12 and impedes cell cycle progression at G2/M

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402134

7 January 2021

Mitogen-activated protein kinase pathway is dispensable for microtubule-active drug-induced Raf-1/Bcl-2 phosphorylation and apoptosis in leukemia cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402134

7 January 2021

Interleukin-3 induces the phosphorylation of a distinct fraction of bcl-2.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402134

7 January 2021

Loss of the bcl-2 phosphorylation loop domain increases resistance of human leukemia cells (U937) to paclitaxel-mediated mitochondrial dysfunction and apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402134

7 January 2021

The apoptotic v-cyclin-CDK6 complex phosphorylates and inactivates Bcl-2.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402134

7 January 2021

Association of insulin receptor substrate proteins with Bcl-2 and their effects on its phosphorylation and antiapoptotic function

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402134

7 January 2021

Checkpoints controlling mitosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402134

7 January 2021

A novel pool of protein phosphatase 2A is associated with microtubules and is regulated during the cell cycle

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402134

7 January 2021

Distinct roles of PP1 and PP2A-like phosphatases in control of microtubule dynamics during mitosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402134

7 January 2021

Okadaic acid induces interphase to mitotic-like microtubule dynamic instability by inactivating rescue

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402134

7 January 2021

Phosphorylation of Bcl-2 protein by CDC2 kinase during G2/M phases and its role in cell cycle regulation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402134

7 January 2021

Molecular effects of paclitaxel: myths and reality (a critical review).

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402134

7 January 2021

Repression of TFIIH transcriptional activity and TFIIH-associated cdk7 kinase activity at mitosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402134

7 January 2021

Ability of the c- mos Product to Associate with and Phosphorylate Tubulin

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402134

7 January 2021

Association of mitogen-activated protein kinase with the microtubule cytoskeleton

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402134

7 January 2021

Control of microtubule dynamics by oncoprotein 18: dissection of the regulatory role of multisite phosphorylation during mitosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402134

7 January 2021

Synergy between Raf and BCL2 in abrogating the cytokine dependency of hematopoietic cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402134

7 January 2021

Characterization of Raf-1 activation in mitosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402134

7 January 2021

Mitotic Raf-1 is stimulated independently of Ras and is active in the cytoplasm

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402134

7 January 2021

Vinblastine-induced phosphorylation of Bcl-2 and Bcl-XL is mediated by JNK and occurs in parallel with inactivation of the Raf-1/MEK/ERK cascade

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402134

7 January 2021

Uncoupling Raf1 from MEK1/2 impairs only a subset of cellular responses to Raf activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402134

7 January 2021

Synergy between the Mos/mitogen-activated protein kinase pathway and loss of p53 function in transformation and chromosome instability

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402134

7 January 2021

Raf-1 protein kinase is important for progesterone-induced Xenopus oocyte maturation and acts downstream of mos

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402134

7 January 2021

c-Jun N-terminal kinase activation in Xenopus laevis eggs and embryos. A possible non-genomic role for the JNK signaling pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402134

7 January 2021

Survival function of ERK1/2 as IL-3-activated, staurosporine-resistant Bcl2 kinases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402134

7 January 2021

Serine protease inhibitor TPCK prevents Taxol-induced cell death and blocks c-Raf-1 and Bcl-2 phosphorylation in human breast carcinoma cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402134

7 January 2021

Bryostatin 1 enhances paclitaxel-induced mitochondrial dysfunction and apoptosis in human leukemia cells (U937) ectopically expressing Bcl-xL

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402134

7 January 2021

MEK inhibition enhances paclitaxel-induced tumor apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402134

7 January 2021

Depletion of p185erbB2, Raf-1 and mutant p53 proteins by geldanamycin derivatives correlates with antiproliferative activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402134

7 January 2021

Bcl-2 undergoes phosphorylation by c-Jun N-terminal kinase/stress-activated protein kinases in the presence of the constitutively active GTP-binding protein Rac1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402134

7 January 2021

Microtubule-interfering Agents Activate c-Jun N-terminal Kinase/Stress-activated Protein Kinase through Both Ras and Apoptosis Signal-regulating Kinase Pathways

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402134

7 January 2021

Microtubule dysfunction induced by paclitaxel initiates apoptosis through both c-Jun N-terminal kinase (JNK)-dependent and -independent pathways in ovarian cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402134

7 January 2021

p53 mediates bcl-2 phosphorylation and apoptosis via activation of the Cdc42/JNK1 pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402134

7 January 2021

Combined effects of aberrant MEK1 activity and BCL2 overexpression on relieving the cytokine dependency of human and murine hematopoietic cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402134

7 January 2021

Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X(L)

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402134

7 January 2021

Ca2+-induced apoptosis through calcineurin dephosphorylation of BAD

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402134

7 January 2021

Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402134

7 January 2021

Myeloid cell leukemia 1 is phosphorylated through two distinct pathways, one associated with extracellular signal-regulated kinase activation and the other with G2/M accumulation or protein phosphatase 1/2A inhibition

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402134

7 January 2021

Medroxyprogesterone acetate inhibits human pancreatic carcinoma cell growth by inducing apoptosis in association with Bcl-2 phosphorylation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402134

7 January 2021

A node between proliferation, apoptosis, and growth arrest

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402134

7 January 2021

Targeted gene disruption of Hsp70-2 results in failed meiosis, germ cell apoptosis, and male infertility

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402134

7 January 2021

Apoptotic pathways: paper wraps stone blunts scissors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402134

7 January 2021

The most unkindest cut of all: on the multiple roles of mammalian caspases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402134

7 January 2021

Genetic analysis of chemoresistance in primary murine lymphomas.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402134

7 January 2021

Identification of small-molecule inhibitors of interaction between the BH3 domain and Bcl-xL

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402134

7 January 2021

Antimycin A mimics a cell-death-inducing Bcl-2 homology domain 3.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.LEU.2402134

7 January 2021

Identifiers

DOI

10.1038/SJ.LEU.2402134

1 reference

PubMed ID

11417471

Dimensions Publication ID

30 July 2017

0 references

1 reference

PubMed ID

11417471