Proliferation of amyloid-β42 aggregates occurs through a secondary nucleation mechanism (Q34346440)

1 August 2017

Proliferation of amyloid-β42 aggregates occurs through a secondary nucleation mechanism (English)

1 reference

1 August 2017

Sara Linse

2

0 references

Daniel Otzen

object named as

Daniel E Otzen

7

0 references

Chris Dobson

9

object named as

Christopher M Dobson

1 reference

1 August 2017

8

Michele Vendruscolo

1 reference

1 August 2017

Samuel I A Cohen

1

1 reference

1 August 2017

Leila M Luheshi

3

1 reference

1 August 2017

Erik Hellstrand

4

1 reference

1 August 2017

Duncan A White

5

1 reference

1 August 2017

Luke Rajah

6

1 reference

1 August 2017

Tuomas P J Knowles

10

1 reference

1 August 2017

language of work or name

English

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publication date

23 May 2013

1 reference

Proceedings of the National Academy of Sciences of the United States of America

1 August 2017

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1 August 2017

110

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1 August 2017

9758-9763

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1 August 2017

24

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Amyloid β-protein aggregation produces highly reproducible kinetic data and occurs by a two-phase process

1 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683769

Direct observation of the interconversion of normal and toxic forms of α-synuclein

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683769

From macroscopic measurements to microscopic mechanisms of protein aggregation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683769

Nucleated polymerization with secondary pathways. II. Determination of self-consistent solutions to growth processes described by non-linear master equations

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683769

Nucleated polymerization with secondary pathways. I. Time evolution of the principal moments

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683769

Amyloid-β forms fibrils by nucleated conformational conversion of oligomers

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683769

Critical nucleus size for disease-related polyglutamine aggregation is repeat-length dependent

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683769

Peripherally applied Abeta-containing inoculates induce cerebral beta-amyloidosis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683769

An analytical solution to the kinetics of breakable filament assembly

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683769

Amyloid seeds formed by cellular uptake, concentration, and aggregation of the amyloid-beta peptide

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683769

Oligomeric amyloid beta associates with postsynaptic densities and correlates with excitatory synapse loss near senile plaques

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683769

A facile method for expression and purification of the Alzheimer's disease-associated amyloid beta-peptide

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683769

Fiber-dependent amyloid formation as catalysis of an existing reaction pathway

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683769

Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid beta-peptide

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683769

3D structure of Alzheimer's amyloid-beta(1-42) fibrils

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683769

Twenty years of the Alzheimer's disease amyloid hypothesis: a genetic perspective

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683769

Mechanism of prion propagation: amyloid growth occurs by monomer addition

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683769

Folding proteins in fatal ways

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683769

Protein folding and misfolding

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683769

Games played by rogue proteins in prion disorders and Alzheimer's disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683769

Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683769

Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683769

Inherent toxicity of aggregates implies a common mechanism for protein misfolding diseases

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683769

Nucleated conformational conversion and the replication of conformational information by a prion determinant

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683769

Kinetics of self-assembling microtubules: an "inverse problem" in biochemistry.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683769

Seeding "one-dimensional crystallization" of amyloid: a pathogenic mechanism in Alzheimer's disease and scrapie?

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683769

Kinetics of nucleation-controlled polymerization. A perturbation treatment for use with a secondary pathway

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683769

Kinetics of sickle hemoglobin polymerization. II. A double nucleation mechanism.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683769

Sickle cell hemoglobin polymerization

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683769

The physical basis of how prion conformations determine strain phenotypes

6 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1218402110

Amyloid: little proteins, big clues.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1218402110

Analysis of protein aggregation kinetics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1218402110

Onset of heterogeneous crystal nucleation in colloidal suspensions

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1218402110

Passive immunotherapy rapidly increases structural plasticity in a mouse model of Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1218402110

Novel mechanistic insight into the molecular basis of amyloid polymorphism and secondary nucleation during amyloid formation

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683769

Detailed Analysis of the Energy Barriers for Amyloid Fibril Growth

27 October 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1218402110

Spontaneous fragmentation of actin filaments in physiological conditions

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1218402110

Aβ40 and Aβ42 Amyloid Fibrils Exhibit Distinct Molecular Recycling Properties

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23703910

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

A theory of linear and helical aggregations of macromolecules

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23703910

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1218402110

1 reference

1 August 2017

0 references

1 reference

1 August 2017

1 reference