The fat mass and obesity associated gene (Fto) regulates activity of the dopaminergic midbrain circuitry (Q34354815)

1 August 2017

The fat mass and obesity associated gene (Fto) regulates activity of the dopaminergic midbrain circuitry (English)

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1 August 2017

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10

Olivier Elemento

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Marcelo O Dietrich

Marcelo O Dietrich

7

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Linda Koch

Linda Koch

5

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Kate D Meyer

Kate D Meyer

3

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Jens C Brüning

17

Jens C Brüning

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1 August 2017

Martin E Hess

1

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1 August 2017

Simon Hess

2

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1 August 2017

Linda A W Verhagen

4

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1 August 2017

Hella S Brönneke

6

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1 August 2017

Sabine D Jordan

8

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1 August 2017

Yogesh Saletore

9

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1 August 2017

Bengt F Belgardt

11

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1 August 2017

Thomas Franz

12

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1 August 2017

Tamas L Horvath

13

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1 August 2017

Ulrich Rüther

14

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1 August 2017

Samie R Jaffrey

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1 August 2017

Peter Kloppenburg

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1 August 2017

language of work or name

English

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publication date

30 June 2013

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16

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1042-1048

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8

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https://scigraph.springernature.com/pub.10.1038/nn.3449

1 August 2017

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cites work

A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity

1 reference

FTO and obesity: a problem for a billion people.

21 January 2018

1 reference

Variation in FTO contributes to childhood obesity and severe adult obesity

21 January 2018

1 reference

An obesity-associated FTO gene variant and increased energy intake in children

21 January 2018

1 reference

The FTO gene and measured food intake in children

21 January 2018

1 reference

A commonly carried allele of the obesity-related FTO gene is associated with reduced brain volume in the healthy elderly

21 January 2018

1 reference

Inverse association of the obesity predisposing FTO rs9939609 genotype with alcohol consumption and risk for alcohol dependence.

21 January 2018

1 reference

Inactivation of the Fto gene protects from obesity

21 January 2018

1 reference

Loss-of-function mutation in the dioxygenase-encoding FTO gene causes severe growth retardation and multiple malformations

21 January 2018

1 reference

The obesity-associated FTO gene encodes a 2-oxoglutarate-dependent nucleic acid demethylase

21 January 2018

1 reference

FTO is expressed in neurones throughout the brain and its expression is unaltered by fasting

21 January 2018

1 reference

Role for the obesity-related FTO gene in the cellular sensing of amino acids

21 January 2018

1 reference

FTO expression is regulated by availability of essential amino acids.

21 January 2018

1 reference

Crystal structure of the FTO protein reveals basis for its substrate specificity

21 January 2018

1 reference

N6-methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO

21 January 2018

1 reference

Comprehensive analysis of mRNA methylation reveals enrichment in 3' UTRs and near stop codons

21 January 2018

1 reference

Topology of the human and mouse m6A RNA methylomes revealed by m6A-seq

21 January 2018

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Neurotransmitter modulation of the GHRH-GH axis.

21 January 2018

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New insights into dopaminergic receptor function using antisense and genetically altered animals

21 January 2018

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The physiology, signaling, and pharmacology of dopamine receptors

21 January 2018

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Induction of a long-lasting AP-1 complex composed of altered Fos-like proteins in brain by chronic cocaine and other chronic treatments.

21 January 2018

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Reward system and addiction: what dopamine does and doesn't do.

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Loss of autoreceptor functions in mice lacking the dopamine transporter.

21 January 2018

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Cocaine supersensitivity and enhanced motivation for reward in mice lacking dopamine D2 autoreceptors

21 January 2018

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Patch-clamp studies in the CNS illustrate a simple new method for obtaining viable neurons in rat brain slices: glycerol replacement of NaCl protects CNS neurons.

21 January 2018

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Leptin receptor signaling in midbrain dopamine neurons regulates feeding

21 January 2018

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Progressive parkinsonism in mice with respiratory-chain-deficient dopamine neurons

21 January 2018

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Dual control of dopamine synthesis and release by presynaptic and postsynaptic dopamine D2 receptors

21 January 2018

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Oxidative demethylation of 3-methylthymine and 3-methyluracil in single-stranded DNA and RNA by mouse and human FTO

21 January 2018

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Targeting the dopamine D2 receptor in schizophrenia

21 January 2018

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Genetics of dopamine receptors and drug addiction: a comprehensive review

21 January 2018

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Dopamine D2 receptors in addiction-like reward dysfunction and compulsive eating in obese rats

21 January 2018

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Brain dopamine and obesity

21 January 2018

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Genetically determined differences in learning from errors

21 January 2018

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High-fat feeding promotes obesity via insulin receptor/PI3K-dependent inhibition of SF-1 VMH neurons

21 January 2018

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Low access resistance perforated patch recordings using amphotericin B.

21 January 2018

1 reference

Perforated-patch recording with gramicidin avoids artifactual changes in intracellular chloride concentration.

21 January 2018

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On the potassium conductance increase activated by GABAB and dopamine D2 receptors in rat substantia nigra neurones.

21 January 2018

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G protein-activated inwardly rectifying K+ (GIRK) currents in dendrites of rat neocortical pyramidal cells.

21 January 2018

1 reference

Bi-directional effects of GABA(B) receptor agonists on the mesolimbic dopamine system

21 January 2018

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Single cocaine exposure in vivo induces long-term potentiation in dopamine neurons

21 January 2018

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Electrophysiological and immunocytochemical characterization of GABA and dopamine neurons in the substantia nigra of the rat.

21 January 2018

1 reference

Revealing global regulatory perturbations across human cancers

21 January 2018

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Disruption of the D2 dopamine receptor alters GH and IGF-I secretion and causes dwarfism in male mice

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23817550

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Association between obesity-related gene FTO and ADHD.

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23817550

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Two cell types in rat substantia nigra zona compacta distinguished by membrane properties and the actions of dopamine and opioids

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23817550

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NN.3449

1 reference

1 August 2017

1 reference