An essential role for the transcription factor HEB in thymocyte survival, Tcra rearrangement and the development of natural killer T cells (Q34357987)

1 August 2017

title

An essential role for the transcription factor HEB in thymocyte survival, Tcra rearrangement and the development of natural killer T cells (English)

1 reference

1 August 2017

0 references

Louise M D'Cruz

1

1 reference

1 August 2017

Jamie Knell

series ordinal

2

1 reference

1 August 2017

Jessica K Fujimoto

series ordinal

3

1 reference

1 August 2017

Ananda W Goldrath

series ordinal

4

1 reference

1 August 2017

language of work or name

English

0 references

publication date

14 February 2010

1 reference

1 August 2017

1 reference

1 August 2017

volume

11

1 reference

1 August 2017

issue

3

1 reference

1 August 2017

page(s)

240-249

1 reference

Intrathymic proliferation wave essential for Valpha14+ natural killer T cell development depends on c-Myc

1 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993240

The gene encoding early growth response 2, a target of the transcription factor NFAT, is required for the development and maturation of natural killer T cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993240

Transcription factor E2-2 is an essential and specific regulator of plasmacytoid dendritic cell development

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993240

The transcription factor PLZF directs the effector program of the NKT cell lineage

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993240

The BTB-zinc finger transcriptional regulator PLZF controls the development of invariant natural killer T cell effector functions

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993240

CD1d-restricted iNKT cells, the 'Swiss-Army knife' of the immune system

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993240

Liver autoimmunity triggered by microbial activation of natural killer T cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993240

Molecular profiling reveals distinct functional attributes of CD1d-restricted natural killer (NK) T cell subsets

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993240

E protein dosage influences brain development more than family member identity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993240

Acquisition of a functional T cell receptor during T lymphocyte development is enforced by HEB and E2A transcription factors

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993240

Control points in NKT-cell development

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993240

The unique role of natural killer T cells in the response to microorganisms

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993240

E2A and HEB are required to block thymocyte proliferation prior to pre-TCR expression

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993240

On the road: progress in finding the unique pathway of invariant NKT cell differentiation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993240

6 July 2018

The biology of NKT cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993240

E proteins and Notch signaling cooperate to promote T cell lineage specification and commitment

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993240

T-bet concomitantly controls migration, survival, and effector functions during the development of Valpha14i NKT cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993240

Helix-loop-helix proteins and lymphocyte development

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993240

Characterization of the early stages of thymic NKT cell development

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993240

Intravascular immune surveillance by CXCR6+ NKT cells patrolling liver sinusoids

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993240

Commitment toward the natural T (iNKT) cell lineage occurs at the CD4+8+ stage of thymic ontogeny

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993240

E2A proteins enforce a proliferation checkpoint in developing thymocytes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993240

Early thymocyte development is regulated by modulation of E2A protein activity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993240

The role of recombination activating gene (RAG) reinduction in thymocyte development in vivo

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993240

Functions of E2A-HEB heterodimers in T-cell development revealed by a dominant negative mutation of HEB

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993240

Requirement for RORgamma in thymocyte survival and lymphoid organ development

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993240

A novel role for HEB downstream or parallel to the pre-TCR signaling pathway during alpha beta thymopoiesis.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993240

Functional replacement of the mouse E2A gene with a human HEB cDNA.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993240

E2A deficiency leads to abnormalities in alphabeta T-cell development and to rapid development of T-cell lymphomas

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993240

Cell cycle regulation of V(D)J recombination-activating protein RAG-2.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993240

Selective requirement for c-Myc at an early stage of V(alpha)14i NKT cell development

6 July 2018

1 reference

Genetic evidence supporting selection of the Valpha14i NKT cell lineage from double-positive thymocyte precursors

21 January 2018

1 reference

T-bet regulates the terminal maturation and homeostasis of NK and Valpha14i NKT cells

21 January 2018

1 reference

An analysis of T cell intrinsic roles of E2A by conditional gene disruption in the thymus.

21 January 2018

1 reference

Inactivation of Notch 1 in immature thymocytes does not perturb CD4 or CD8T cell development.

21 January 2018

1 reference

Interplay between RORgammat, Egr3, and E proteins controls proliferation in response to pre-TCR signals.

21 January 2018

1 reference

Regulation of the TCRalpha repertoire by the survival window of CD4(+)CD8(+) thymocytes.

21 January 2018

1 reference

Increased interleukin 4 and immunoglobulin E production in transgenic mice overexpressing NK1 T cells.

21 January 2018

1 reference

Activation of natural killer T cells by glycolipids

21 January 2018

1 reference

Quantitative and qualitative changes in V-J alpha rearrangements during mouse thymocytes differentiation: implication for a limited T cell receptor alpha chain repertoire

21 January 2018

1 reference

A conserved degradation signal regulates RAG-2 accumulation during cell division and links V(D)J recombination to the cell cycle

21 January 2018

1 reference

12 December 2020

Role for IL-15/IL-15 receptor beta-chain in natural killer 1.1+ T cell receptor-alpha beta+ cell development

1 reference

12 December 2020

Regulation of NKT cell development by SAP, the protein defective in XLP

1 reference

12 December 2020

Multiple constraints at the level of TCRalpha rearrangement impact Valpha14i NKT cell development

1 reference

12 December 2020

Identifiers

DOI

10.1038/NI.1845

1 reference

1 August 2017

1 reference

1 August 2017

1 reference