IKAROS deletions dictate a unique gene expression signature in patients with adult B-cell acute lymphoblastic leukemia (Q34358106)

1 August 2017

IKAROS deletions dictate a unique gene expression signature in patients with adult B-cell acute lymphoblastic leukemia (English)

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1 August 2017

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lymphoblastic leukemia

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B-cell acute lymphoblastic leukemia

inferred from title

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20

Markus Müschen

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Sandra Durante

Sandra Durante

14

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Nunzio Iraci

Nunzio Iraci

2

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Monica Messina

Monica Messina

3

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Annalisa Lonetti

Annalisa Lonetti

4

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Clelia Tiziana Storlazzi

Clelia Tiziana Storlazzi

11

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Simona Soverini

Simona Soverini

16

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Marco Vignetti

Marco Vignetti

15

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Cristina Papayannidis

Cristina Papayannidis

8

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Emanuele Valli

Emanuele Valli

6

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Giovanni Martinelli

22

Giovanni Martinelli

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1 August 2017

19

Michele Baccarani

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1 August 2017

1

Ilaria Iacobucci

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1 August 2017

12

Emanuela Ottaviani

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1 August 2017

18

Robin Foà

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1 August 2017

17

Fabrizio Pane

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1 August 2017

9

Francesca Paoloni

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1 August 2017

5

Sabina Chiaretti

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1 August 2017

13

Viviana Guadagnuolo

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1 August 2017

21

Giovanni Perini

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1 August 2017

Anna Ferrari

7

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1 August 2017

Antonella Vitale

10

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1 August 2017

Markus Müschen

20

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1 August 2017

language of work or name

English

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publication date

25 July 2012

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1 August 2017

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1 August 2017

7

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7

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1 August 2017

e40934

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Creative Commons Attribution 4.0 International

1 August 2017

start time

25 July 2012

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

Integrated use of minimal residual disease classification and IKZF1 alteration status accurately predicts 79% of relapses in pediatric acute lymphoblastic leukemia

1 reference

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The PAX5 gene is frequently rearranged in BCR-ABL1-positive acute lymphoblastic leukemia but is not associated with outcome. A report on behalf of the GIMEMA Acute Leukemia Working Party

6 July 2018

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IKZF1 deletions predict relapse in uniformly treated pediatric precursor B-ALL.

6 July 2018

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Gene expression profile of protein kinases reveals a distinctive signature in chronic lymphocytic leukemia and in vitro experiments support a role of second generation protein kinase inhibitors.

6 July 2018

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Self-renewal of the long-term reconstituting subset of hematopoietic stem cells is regulated by Ikaros.

6 July 2018

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IKZF1 (Ikaros) deletions in BCR-ABL1-positive acute lymphoblastic leukemia are associated with short disease-free survival and high rate of cumulative incidence of relapse: a GIMEMA AL WP report

6 July 2018

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Pre-B cell receptor-mediated cell cycle arrest in Philadelphia chromosome-positive acute lymphoblastic leukemia requires IKAROS function

6 July 2018

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Identification and molecular characterization of recurrent genomic deletions on 7p12 in the IKZF1 gene in a large cohort of BCR-ABL1-positive acute lymphoblastic leukemia patients: on behalf of Gruppo Italiano Malattie Ematologiche dell'Adulto Acute

6 July 2018

1 reference

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JAK mutations in high-risk childhood acute lymphoblastic leukemia

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405023

Ikaros deletions are associated with poor prognosis in acute lymphoblastic leukemia

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405023

Genome-wide lineage-specific transcriptional networks underscore Ikaros-dependent lymphoid priming in hematopoietic stem cells

6 July 2018

1 reference

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A subtype of childhood acute lymphoblastic leukaemia with poor treatment outcome: a genome-wide classification study

6 July 2018

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Deletion of IKZF1 and prognosis in acute lymphoblastic leukemia

6 July 2018

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Global genomic characterization of acute lymphoblastic leukemia

6 July 2018

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Integrated analysis of homozygous deletions, focal amplifications, and sequence alterations in breast and colorectal cancers

6 July 2018

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Integration of genomic and gene expression data of childhood ALL without known aberrations identifies subgroups with specific genetic hallmarks

6 July 2018

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Cloning of genes involved in chromosomal translocations by high-resolution single nucleotide polymorphism genomic microarray

6 July 2018

1 reference

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Regulation of B cell fate commitment and immunoglobulin heavy-chain gene rearrangements by Ikaros.

6 July 2018

1 reference

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Ikaros dominant negative isoform (Ik6) induces IL-3-independent survival of murine pro-B lymphocytes by activating JAK-STAT and up-regulating Bcl-xl levels

6 July 2018

1 reference

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Molecular allelokaryotyping of pediatric acute lymphoblastic leukemias by high-resolution single nucleotide polymorphism oligonucleotide genomic microarray

6 July 2018

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Genome-wide analysis of genetic alterations in acute lymphoblastic leukaemia

6 July 2018

1 reference

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Karyotype is an independent prognostic factor in adult acute lymphoblastic leukemia (ALL): analysis of cytogenetic data from patients treated on the Medical Research Council (MRC) UKALLXII/Eastern Cooperative Oncology Group (ECOG) 2993 trial

6 July 2018

1 reference

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Molecular genetics of acute lymphoblastic leukemia

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405023

Molecular genetic events in adult acute lymphoblastic leukemia

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405023

DAVID: Database for Annotation, Visualization, and Integrated Discovery

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405023

Haematopoietic cell-fate decisions, chromatin regulation and ikaros

6 July 2018

1 reference

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Model-based analysis of oligonucleotide arrays: expression index computation and outlier detection

6 July 2018

1 reference

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Defects in hemopoietic stem cell activity in Ikaros mutant mice

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405023

Ikaros in hemopoietic lineage determination and homeostasis

6 July 2018

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DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139

6 July 2018

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Hematopoietic stem cells and lymphoid progenitors express different Ikaros isoforms, and Ikaros is localized to heterochromatin in immature lymphocytes.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405023

Selective defects in the development of the fetal and adult lymphoid system in mice with an Ikaros null mutation

6 July 2018

1 reference

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The Ikaros gene encodes a family of functionally diverse zinc finger DNA-binding proteins

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405023

The Ikaros gene is required for the development of all lymphoid lineages

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3405023

High-resolution genomic profiling of childhood ALL reveals novel recurrent genetic lesions affecting pathways involved in lymphocyte differentiation and cell cycle progression.

6 July 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0040934

Transcription factor EBF restricts alternative lineage options and promotes B cell fate commitment independently of Pax5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0040934

Repopulating defect of mismatch repair–deficient hematopoietic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0040934

Cell-cycle restriction limits DNA damage and maintains self-renewal of leukaemia stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0040934

Evaluation of the long-term reconstituting subset of hematopoietic stem cells with CD150

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0040934

Clinical utility of microarray-based gene expression profiling in the diagnosis and subclassification of leukemia: report from the International Microarray Innovations in Leukemia Study Group

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0040934

BCR–ABL1 lymphoblastic leukaemia is characterized by the deletion of Ikaros

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0040934

A dominant mutation in the Ikaros gene leads to rapid development of leukemia and lymphoma

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22848414

12 December 2020

inferred from PubMed ID database lookup

Acute lymphoblastic leukemia

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22848414

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1371/JOURNAL.PONE.0040934

1 reference

release_hlbg6klanzauhfwhbkkrhpakb4

1 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/hlbg6klanzauhfwhbkkrhpakb4

24 November 2022

mapped directly with Wikidata item

PMCID

3405023

1 reference

1 August 2017

1 reference