Selective inhibition of histone deacetylase 6 (HDAC6) induces DNA damage and sensitizes transformed cells to anticancer agents (Q34358718)

1 August 2017

Selective inhibition of histone deacetylase 6 (HDAC6) induces DNA damage and sensitizes transformed cells to anticancer agents (English)

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1 August 2017

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Mandana Namdar

1

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1 August 2017

Gisela Perez

series ordinal

2

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1 August 2017

Lang Ngo

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3

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1 August 2017

Paul A Marks

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4

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1 August 2017

language of work or name

English

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publication date

29 October 2010

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Proceedings of the National Academy of Sciences of the United States of America

1 August 2017

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1 August 2017

107

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1 August 2017

46

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1 August 2017

20003-20008

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describes a project that uses

1 August 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2993347/fullTextXML

inferred from PubMed Central ID database lookup

limma

1 reference

22 June 2022

https://europepmc.org/article/PMC/2993347

inferred from PubMed Central ID database lookup

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HDAC inhibitor PCI-24781 decreases RAD51 expression and inhibits homologous recombination

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Intrinsic apoptotic and thioredoxin pathways in human prostate cancer cell response to histone deacetylase inhibitor

6 July 2018

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HDAC6-p97/VCP controlled polyubiquitin chain turnover

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The synergistic combination of the farnesyl transferase inhibitor lonafarnib and paclitaxel enhances tubulin acetylation and requires a functional tubulin deacetylase

6 July 2018

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Induction of a cell stress response gene RTP801 by DNA damaging agent methyl methanesulfate through CCAA/enhancer binding protein

6 July 2018

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6 July 2018

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The deacetylase HDAC6 regulates aggresome formation and cell viability in response to misfolded protein stress

6 July 2018

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Inhibition of histone deacetylase increases cytotoxicity to anticancer drugs targeting DNA

6 July 2018

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Domain-selective small-molecule inhibitor of histone deacetylase 6 (HDAC6)-mediated tubulin deacetylation

6 July 2018

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HDAC6 is a microtubule-associated deacetylase

6 July 2018

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6 July 2018

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6 July 2018

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CHOP is implicated in programmed cell death in response to impaired function of the endoplasmic reticulum

6 July 2018

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Inhibition of histone deacetylase 6 acetylates and disrupts the chaperone function of heat shock protein 90: a novel basis for antileukemia activity of histone deacetylase inhibitors.

6 July 2018

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Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1013754107

HDAC6 inhibition enhances 17-AAG--mediated abrogation of hsp90 chaperone function in human leukemia cells

21 January 2018

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Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1013754107

Histone deacetylase inhibitors sensitize prostate cancer cells to agents that produce DNA double-strand breaks by targeting Ku70 acetylation.

21 January 2018

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Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1013754107

Chromosome regions enriched in hyperacetylated histone H4 are preferred sites for endonuclease- and radiation-induced breakpoints

21 January 2018

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12 December 2020

Pharmacokinetics of high-dose etoposide (VP-16-213) administered to cancer patients

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12 December 2020

Comparative pharmacokinetics of free doxorubicin and doxorubicin entrapped in cardiolipin liposomes

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12 December 2020

PARP cleavage as a means of assessing apoptosis

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12 December 2020

Identifiers

DOI

10.1073/PNAS.1013754107

1 reference

1 August 2017

0 references

1 reference

1 August 2017

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