Toward testing the hypothesis that group B coxsackieviruses (CVB) trigger insulin-dependent diabetes: inoculating nonobese diabetic mice with CVB markedly lowers diabetes incidence. (Q34359584)

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English	Toward testing the hypothesis that group B coxsackieviruses (CVB) trigger insulin-dependent diabetes: inoculating nonobese diabetic mice with CVB markedly lowers diabetes incidence.	scientific article

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14 December 2019

Toward testing the hypothesis that group B coxsackieviruses (CVB) trigger insulin-dependent diabetes: inoculating nonobese diabetic mice with CVB markedly lowers diabetes incidence (English)

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14 December 2019

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14 December 2019

Steven D Carson

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14 December 2019

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S Tracy

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K M Drescher

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K-S Kim

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S Pirruccello

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P H Lane

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J R Romero

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J S Leser

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14 December 2019

Journal of Virology

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14 December 2019

12097-12111

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14 December 2019

Myocarditis in newborns, caused by coxsackie virus; clinical and pathological data.

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Target cell defense prevents the development of diabetes after viral infection.

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Coxsackievirus B3 replication is reduced by inhibition of the extracellular signal-regulated kinase (ERK) signaling pathway

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The apoptotic capability of coxsackievirus B3 is influenced by the efficient interaction between the capsid protein VP2 and the proapoptotic host protein Siva

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Lipopolysaccharide-activated B cells down-regulate Th1 immunity and prevent autoimmune diabetes in nonobese diabetic mice

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The NOD mouse model of type 1 diabetes: as good as it gets?

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T cells contribute to disease severity during coxsackievirus B4 infection.

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Diabetes induced by Coxsackie virus: initiation by bystander damage and not molecular mimicry

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Enterovirus infections and insulin dependent diabetes mellitus--evidence for causality.

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The murine CAR homolog is a receptor for coxsackie B viruses and adenoviruses.

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Pathogenesis and treatment of virus-induced autoimmune diabetes: novel insights gained from the RIP-LCMV transgenic mouse model

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Aspects of the etiology, prediction, and prevention of insulin-dependent diabetes mellitus in childhood

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Identification of a single amino acid residue in the capsid protein VP1 of coxsackievirus B4 that determines the virulent phenotype

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Cellular immunity to a determinant common to glutamate decarboxylase and coxsackie virus in insulin-dependent diabetes

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The cardiovirulent phenotype of coxsackievirus B3 is determined at a single site in the genomic 5' nontranslated region.

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6 July 2018

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A case-control study of group B Coxsackievirus immunoglobulin M antibody prevalence and HLA-DR antigens in newly diagnosed cases of insulin-dependent diabetes mellitus

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Susceptibility of mice to group B coxsackie virus is influenced by the diabetic gene

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No evidence for an association of coxsackie virus infections during pregnancy and early childhood with development of islet autoantibodies in offspring of mothers or fathers with type 1 diabetes

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Follow-up of children infected in a coxsackievirus B-3 and B-4 outbreak: no evidence of diabetes mellitus

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Severity of disease induced by a pancreatropic Coxsackie B4 virus correlates with the H-2Kq locus of the major histocompatibility complex

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=136885

27 October 2018

Generation of an infectious cDNA of a highly cardiovirulent coxsackievirus B3(CVB3m) and comparison to other infectious CVB3 cDNAs

1 reference

https://pubmed.ncbi.nlm.nih.gov/12414951

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acute myocarditis. Rapid diagnosis by PCR in children

1 reference

https://pubmed.ncbi.nlm.nih.gov/12414951

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Myocarditis in children with dilated cardiomyopathy: incidence and outcome after dual therapy immunosuppression

1 reference

https://pubmed.ncbi.nlm.nih.gov/12414951

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tracheal aspirate as a substrate for polymerase chain reaction detection of viral genome in childhood pneumonia and myocarditis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12414951

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Swedish childhood diabetes study. Vaccinations and infections as risk determinants for diabetes in childhood

1 reference

https://pubmed.ncbi.nlm.nih.gov/12414951

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular cloning and partial characterization of the coxsackievirus B3 genome

1 reference

https://pubmed.ncbi.nlm.nih.gov/12414951

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A search for the presence of the enteroviral capsid protein VP1 in pancreases of patients with type 1 (insulin-dependent) diabetes and pancreases and hearts of infants who died of coxsackieviral myocarditis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12414951

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

T-cell responses to enterovirus antigens in children with type 1 diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/12414951

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acceleration of type 1 diabetes by a coxsackievirus infection requires a preexisting critical mass of autoreactive T-cells in pancreatic islets

1 reference

https://pubmed.ncbi.nlm.nih.gov/12414951

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Altered expression of Bag-1 in Coxsackievirus B3 infected mouse heart

1 reference

https://pubmed.ncbi.nlm.nih.gov/12414951

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The genetic susceptibility to type 1 (insulin-dependent) diabetes: analysis of the HLA-DR association

1 reference

https://pubmed.ncbi.nlm.nih.gov/12414951

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential behaviour in pancreas and heart of two coxsackievirus B3 variants

1 reference

https://pubmed.ncbi.nlm.nih.gov/12414951

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Diabetes in identical twins. A study of 200 pairs

1 reference

https://pubmed.ncbi.nlm.nih.gov/12414951

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enterovirus infections in acute pancreatitis - a possible etiological connection

1 reference

https://pubmed.ncbi.nlm.nih.gov/12414951

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Coxsackie viruses

1 reference

https://pubmed.ncbi.nlm.nih.gov/12414951

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A point mutation in VP1 of coxsackievirus B4 alters antigenicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/12414951

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Early infection and subsequent insulin dependent diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/12414951

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The pathogenesis of insulin-dependent diabetes mellitus

1 reference

https://pubmed.ncbi.nlm.nih.gov/12414951

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Murine acinar pancreatitis preceding necrotizing myocarditis after Coxsackievirus B3 inoculation

1 reference

https://pubmed.ncbi.nlm.nih.gov/12414951

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Coxsackievirus-associated pancreatitis mimicking metastatic carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/12414951

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Coxsackievirus B3 from an infectious cDNA copy of the genome is cardiovirulent in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/12414951

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Severe pancreatitis and fatty liver progressing to cirrhosis associated with Coxsackie B4 infection in a three year old with alpha-1-antitrypsin deficiency

1 reference

https://pubmed.ncbi.nlm.nih.gov/12414951

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An infectious cDNA copy of the genome of a non-cardiovirulent coxsackievirus B3 strain: its complete sequence analysis and comparison to the genomes of cardiovirulent coxsackieviruses

1 reference

https://pubmed.ncbi.nlm.nih.gov/12414951

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Requirements for viral-mediated autoimmune diabetes: beta-cell damage and immune infiltration

1 reference

https://pubmed.ncbi.nlm.nih.gov/12414951

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Group B coxsackievirus myocarditis and pancreatitis: connection between viral virulence phenotypes in mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12414951

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Concordance for type 1 diabetes in identical twins is affected by insulin genotype

1 reference

https://pubmed.ncbi.nlm.nih.gov/12414951

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/JVI.76.23.12097-12111.2002

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12414951%20AND%20SRC:MED&resulttype=core&format=json

14 December 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12414951%20AND%20SRC:MED&resulttype=core&format=json

14 December 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12414951%20AND%20SRC:MED&resulttype=core&format=json

14 December 2019

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