Role of interleukin-13 in fibrosis, particularly systemic sclerosis (Q34360300)

1 August 2017

Role of interleukin-13 in fibrosis, particularly systemic sclerosis (English)

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1 August 2017

Steven O'Reilly

1

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1 August 2017

25 July 2013

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1 August 2017

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1 August 2017

39

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1 August 2017

6

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1 August 2017

593-596

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Cellular and molecular mechanisms of fibrosis

1 August 2017

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Systemic sclerosis: a prototypic multisystem fibrotic disorder

21 January 2018

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Evaluation of interleukin 13 polymorphisms in systemic sclerosis.

21 January 2018

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Interleukin 13, a T-cell-derived cytokine that regulates human monocyte and B-cell function

21 January 2018

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Nuocytes represent a new innate effector leukocyte that mediates type-2 immunity

21 January 2018

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Regulation and function of the interleukin 13 receptor alpha 2 during a T helper cell type 2-dominant immune response

21 January 2018

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Fibrotic disease and the T(H)1/T(H)2 paradigm

21 January 2018

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Schistosome infection of transgenic mice defines distinct and contrasting pathogenic roles for IL-4 and IL-13: IL-13 is a profibrotic agent

21 January 2018

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Production of interleukin 13 by alveolar macrophages from normal and fibrotic lung

21 January 2018

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Pulmonary expression of interleukin-13 causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic abnormalities, and eotaxin production

21 January 2018

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Interleukin (IL) 4 and IL-13 act on human lung fibroblasts. Implication in asthma.

21 January 2018

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An IL-13 inhibitor blocks the development of hepatic fibrosis during a T-helper type 2-dominated inflammatory response

21 January 2018

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Novel role of IL-13 in fibrosis induced by nonalcoholic steatohepatitis and its amelioration by IL-13R-directed cytotoxin in a rat model

21 January 2018

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Interaction of IL-13 and C10 in the pathogenesis of bleomycin-induced pulmonary fibrosis

21 January 2018

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Interleukin-13 induces tissue fibrosis by selectively stimulating and activating transforming growth factor beta(1).

21 January 2018

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IL-13 promotes collagen accumulation in Crohn's disease fibrosis by down-regulation of fibroblast MMP synthesis: a role for innate lymphoid cells?

21 January 2018

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Protection from fluorescein isothiocyanate-induced fibrosis in IL-13-deficient, but not IL-4-deficient, mice results from impaired collagen synthesis by fibroblasts

21 January 2018

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Early T cell activation in the skin from patients with systemic sclerosis

21 January 2018

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Role of IL-13 in systemic sclerosis

21 January 2018

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GATA-3 up-regulation in CD8+ T cells as a biomarker of immune dysfunction in systemic sclerosis, resulting in excessive interleukin-13 production.

21 January 2018

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Interleukin-13-producing CD8+ T cells mediate dermal fibrosis in patients with systemic sclerosis

21 January 2018

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Tumor necrosis factor-costimulated T lymphocytes from patients with systemic sclerosis trigger collagen production in fibroblasts.

21 January 2018

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Interleukin-4 induces the activation and collagen production of cultured human intrahepatic fibroblasts via the STAT-6 pathway

21 January 2018

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IL-1 receptor accessory protein and ST2 comprise the IL-33 receptor complex

21 January 2018

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IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines

21 January 2018

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IL-33 augments substance P-induced VEGF secretion from human mast cells and is increased in psoriatic skin

21 January 2018

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Interleukin-33 overexpression is associated with liver fibrosis in mice and humans.

21 January 2018

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Essential role of Stat6 in IL-4 signalling

21 January 2018

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Signal transducer and activator of transcription factor 6 (Stat6)-deficient mice are protected from antigen-induced airway hyperresponsiveness and mucus production

21 January 2018

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Regulatory effect of extracellular signal-regulated kinases (ERK) on type I collagen synthesis in human dermal fibroblasts stimulated by IL-4 and IL-13.

21 January 2018

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Lebrikizumab treatment in adults with asthma

21 January 2018

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Treatment of allergic airway inflammation and hyperresponsiveness by antisense-induced local blockade of GATA-3 expression

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1002/BIOF.1117

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1 August 2017

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PubMed ID

23893513