Trichostatin A accentuates doxorubicin-induced hypertrophy in cardiac myocytes. (Q34361211)

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15 February 2020

title

Trichostatin A accentuates doxorubicin-induced hypertrophy in cardiac myocytes (English)

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15 February 2020

7

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15 February 2020

1

Tom C Karagiannis

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15 February 2020

3

Katherine Ververis

1 reference

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15 February 2020

author name string

Ann J E Lin

2

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15 February 2020

Lisa Chang

4

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15 February 2020

Michelle M Tang

5

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15 February 2020

Jun Okabe

6

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15 February 2020

publication date

1 October 2010

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15 February 2020

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15 February 2020

volume

2

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15 February 2020

issue

10

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15 February 2020

page(s)

659-668

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The clinical development of histone deacetylase inhibitors as targeted anticancer drugs

15 February 2020

cites work

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Quantification of gammaH2AX foci in response to ionising radiation.

6 July 2018

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Quantifying pharmacologic suppression of cellular senescence: prevention of cellular hypertrophy versus preservation of proliferative potential

6 July 2018

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Growth and aging: a common molecular mechanism

6 July 2018

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gammaH2AX: a sensitive molecular marker of DNA damage and repair

6 July 2018

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Rational combinations using HDAC inhibitors

6 July 2018

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Histone acetyltransferase inhibitors and preclinical studies

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Rapamycin decelerates cellular senescence

6 July 2018

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Histone deacetylase inhibitors: Potential in cancer therapy

6 July 2018

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Enhancing the apoptotic and therapeutic effects of HDAC inhibitors

6 July 2018

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Clinical and biological effects of valproic acid as a histone deacetylase inhibitor on tumor and surrogate tissues: phase I/II trial of valproic acid and epirubicin/FEC.

6 July 2018

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Development of vorinostat: current applications and future perspectives for cancer therapy

6 July 2018

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ERKs/p53 signal transduction pathway is involved in doxorubicin-induced apoptosis in H9c2 cells and cardiomyocytes

6 July 2018

1 reference

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Zn(II)-dependent histone deacetylase inhibitors: suberoylanilide hydroxamic acid and trichostatin A.

6 July 2018

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Induction of several cytochrome P450 genes by doxorubicin in H9c2 cells.

6 July 2018

1 reference

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Morphological alterations induced by doxorubicin on H9c2 myoblasts: nuclear, mitochondrial, and cytoskeletal targets

6 July 2018

1 reference

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Histone deacetylase inhibitors in lymphoma and solid malignancies

6 July 2018

1 reference

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Effect of valproic acid on radiation-induced DNA damage in euchromatic and heterochromatic compartments

6 July 2018

1 reference

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Clinical potential of histone deacetylase inhibitors as stand alone therapeutics and in combination with other chemotherapeutics or radiotherapy for cancer

6 July 2018

1 reference

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Histone deacetylase inhibitors: overview and perspectives

6 July 2018

1 reference

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Plantainoside D protects adriamycin-induced apoptosis in H9c2 cardiac muscle cells via the inhibition of ROS generation and NF-kappaB activation

6 July 2018

1 reference

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Calcineurin activation is not necessary for Doxorubicin-induced hypertrophy in H9c2 embryonic rat cardiac cells: involvement of the phosphoinositide 3-kinase-Akt pathway

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993796

Multiple actions of pifithrin-alpha on doxorubicin-induced apoptosis in rat myoblastic H9c2 cells

6 July 2018

1 reference

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Thrombopoietin protects against in vitro and in vivo cardiotoxicity induced by doxorubicin.

6 July 2018

1 reference

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DNA damage is an early event in doxorubicin-induced cardiac myocyte death

6 July 2018

1 reference

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Modulation of cellular radiation responses by histone deacetylase inhibitors

6 July 2018

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Histone deacetylase inhibitors and the promise of epigenetic (and more) treatments for cancer

6 July 2018

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Inhibitory effects of rosmarinic acid on adriamycin-induced apoptosis in H9c2 cardiac muscle cells by inhibiting reactive oxygen species and the activations of c-Jun N-terminal kinase and extracellular signal-regulated kinase

6 July 2018

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Histone deacetylase inhibitors radiosensitize human melanoma cells by suppressing DNA repair activity

6 July 2018

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The liposomal formulation of doxorubicin

6 July 2018

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Carvedilol prevents doxorubicin-induced free radical release and apoptosis in cardiomyocytes in vitro

6 July 2018

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A ternary complex of transcription factors, Nishéd and NFATc4, and co-activator p300 bound to an intronic sequence, intronic regulatory element, is pivotal for the up-regulation of myosin light chain-2v gene in cardiac hypertrophy

6 July 2018

1 reference

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Cardiac hypertrophy and histone deacetylase-dependent transcriptional repression mediated by the atypical homeodomain protein Hop

6 July 2018

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Congestive heart failure in patients treated with doxorubicin: a retrospective analysis of three trials

6 July 2018

1 reference

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Cardiac hypertrophy: the good, the bad, and the ugly

6 July 2018

1 reference

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Class II histone deacetylases act as signal-responsive repressors of cardiac hypertrophy

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993796

Precipitous release of methyl-CpG binding protein 2 and histone deacetylase 1 from the methylated human multidrug resistance gene (MDR1) on activation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993796

Human heart cytosolic reductases and anthracycline cardiotoxicity

6 July 2018

1 reference

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Apoptotic events in a human ovarian cancer cell line exposed to anthracyclines

6 July 2018

1 reference

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Control of cardiac myosin heavy chain gene expression

6 July 2018

1 reference

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Modulation of L-type calcium channel expression during retinoic acid-induced differentiation of H9C2 cardiac cells.

6 July 2018

1 reference

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A critical evaluation of the mechanisms of action proposed for the antitumor effects of the anthracycline antibiotics adriamycin and daunorubicin

6 July 2018

1 reference

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DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139

6 July 2018

1 reference

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Anthracyclines in the treatment of cancer. An overview

6 July 2018

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Adriamycin cardiomyopathy: pathophysiology and prevention

6 July 2018

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Differential expression of the myocyte enhancer factor 2 family of transcription factors in development: the cardiac factor BBF-1 is an early marker for cardiogenesis

6 July 2018

1 reference

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Doxorubicin-induced Id2A gene transcription is targeted at an activating transcription factor/cyclic AMP response element motif through novel mechanisms involving protein kinases distinct from protein kinase C and protein kinase A

6 July 2018

1 reference

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The anthracycline antineoplastic drugs

6 July 2018

1 reference

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A clinicopathologic analysis of adriamycin cardiotoxicity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993796

Doxorubicin cardiotoxicity: analysis of prevailing hypotheses

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993796

Regulation of cardiac gene expression during myocardial growth and hypertrophy: molecular studies of an adaptive physiologic response

6 July 2018

1 reference

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The anthracyclines: will we ever find a better doxorubicin?

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993796

Signaling mechanisms for the activation of an embryonic gene program during the hypertrophy of cardiac ventricular muscle

6 July 2018

1 reference

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Properties of a clonal muscle cell line from rat heart

6 July 2018

1 reference

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A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993796

The epigenetic modifier, valproic acid, enhances radiation sensitivity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993796

Edaravone, a potent free radical scavenger, prevents anthracycline-induced myocardial cell death

27 October 2018

1 reference

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Histone deacetylase inhibitors sensitize prostate cancer cells to agents that produce DNA double-strand breaks by targeting Ku70 acetylation.

27 October 2018

1 reference

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Phenylbutyrate, a histone deacetylase inhibitor, protects against Adriamycin-induced cardiac injury

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993796

Disparity of histone deacetylase inhibition on repair of radiation-induced DNA damage on euchromatin and constitutive heterochromatin compartments.

27 October 2018

1 reference

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Histone deacetylase inhibition by valproic acid down-regulates c-FLIP/CASH and sensitizes hepatoma cells towards CD95- and TRAIL receptor-mediated apoptosis and chemotherapy.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993796

The histone deacetylase inhibitor, Trichostatin A, enhances radiation sensitivity and accumulation of gammaH2A.X.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993796

Protection against doxorubicin cardiomyopathy in rats: role of phosphodiesterase inhibitors type 4.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993796

Dose-dependent blockade to cardiomyocyte hypertrophy by histone deacetylase inhibitors

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993796

Identification and validation of selective upregulation of ventricular myosin light chain type 2 mRNA in idiopathic dilated cardiomyopathy.

27 October 2018

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New Drug Delivery Nanosystem Combining Liposomal and Dendrimeric Technology (Liposomal Locked-In Dendrimers) for Cancer Therapy

27 October 2018

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12 December 2020

Adriamycin: the role of lipid peroxidation in cardiac toxicity and tumor response

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12 December 2020

Anthracycline antibiotic-stimulated superoxide, hydrogen peroxide, and hydroxyl radical production by NADH dehydrogenase

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12 December 2020

Adriamycin: protection from cell death by removal of extracellular drug

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12 December 2020

Identifiers

DOI

10.18632/AGING.100203

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20930262%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20930262%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

PubMed publication ID

20930262

1 reference