Regulation of P-Rex1 by phosphatidylinositol (3,4,5)-trisphosphate and Gbetagamma subunits (Q34367882)

1 August 2017

Regulation of P-Rex1 by phosphatidylinositol (3,4,5)-trisphosphate and Gbetagamma subunits (English)

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1 August 2017

6

Heidi C E Welch

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1 August 2017

Sonja Krugmann

2

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Leonard R. Stephens

object named as

Len R Stephens

series ordinal

8

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Phillip Thomas Hawkins

object named as

Phillip T Hawkins

series ordinal

7

0 references

Kirsti Hill

series ordinal

1

object named as

Kirsti Hill

1 reference

1 August 2017

4

W John Coadwell

1 reference

1 August 2017

5

Peter Finan

1 reference

1 August 2017

Simon R Andrews

3

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PubMed ID

15545267

1 August 2017

language of work or name

English

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publication date

15 November 2004

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Journal of Biological Chemistry

1 August 2017

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1 August 2017

280

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1 August 2017

6

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1 August 2017

4166-4173

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P-Rex1, a PtdIns(3,4,5)P3- and Gbetagamma-regulated guanine-nucleotide exchange factor for Rac

1 August 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411262200

P-Rex2, a new guanine-nucleotide exchange factor for Rac

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411262200

P-REX2, a novel PI-3-kinase sensitive Rac exchange factor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411262200

Guanine nucleotide exchange factors for Rho GTPases: turning on the switch

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411262200

Phosphotyrosine-dependent activation of Rac-1 GDP/GTP exchange by the vav proto-oncogene product

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411262200

Induction of rac-guanine nucleotide exchange activity of Ras-GRF1/CDC25(Mm) following phosphorylation by the nonreceptor tyrosine kinase Src.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411262200

Ca2+/calmodulin-dependent protein kinase II regulates Tiam1 by reversible protein phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411262200

Phosphoinositide 3-kinase-dependent activation of Rac.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411262200

EPS8 and E3B1 transduce signals from Ras to Rac

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411262200

Structural basis for relief of autoinhibition of the Dbl homology domain of proto-oncogene Vav by tyrosine phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411262200

Crystal structure of the Dbl and pleckstrin homology domains from the human Son of sevenless protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411262200

Crystal structure of Rac1 in complex with the guanine nucleotide exchange region of Tiam1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411262200

Role of substrates and products of PI 3-kinase in regulating activation of Rac-related guanosine triphosphatases by Vav

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411262200

Control of intramolecular interactions between the pleckstrin homology and Dbl homology domains of Vav and Sos1 regulates Rac binding.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411262200

Quantitative Analysis of the Effect of Phosphoinositide Interactions on the Function of Dbl Family Proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411262200

G Protein betagamma subunits stimulate p114RhoGEF, a guanine nucleotide exchange factor for RhoA and Rac1: regulation of cell shape and reactive oxygen species production

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411262200

G protein beta gamma subunit-dependent Rac-guanine nucleotide exchange activity of Ras-GRF1/CDC25(Mm)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411262200

Directional sensing requires G beta gamma-mediated PAK1 and PIX alpha-dependent activation of Cdc42.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411262200

Characterizing the interactions between the two subunits of the p101/p110gamma phosphoinositide 3-kinase and their role in the activation of this enzyme by G beta gamma subunits

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411262200

Sites important for PLCbeta2 activation by the G protein betagamma subunit map to the sides of the beta propeller structure

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411262200

Sites for Galpha binding on the G protein beta subunit overlap with sites for regulation of phospholipase Cbeta and adenylyl cyclase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411262200

PDZ domains-glue and guide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411262200

The isolation and characterization of cDNA encoding human and rat brain inositol polyphosphate 4-phosphatase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411262200

A null mutation in inositol polyphosphate 4-phosphatase type I causes selective neuronal loss in weeble mutant mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411262200

Identification of ARAP3, a novel PI3K effector regulating both Arf and Rho GTPases, by selective capture on phosphoinositide affinity matrices

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411262200

Keeping G proteins at bay: a complex between G protein-coupled receptor kinase 2 and Gbetagamma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411262200

Differential association of the pleckstrin homology domains of phospholipases C-beta 1, C-beta 2, and C-delta 1 with lipid bilayers and the beta gamma subunits of heterotrimeric G proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411262200

Phosphoinositide 3-kinase activates Rac by entering in a complex with Eps8, Abi1, and Sos-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411262200

SWAP-70 is a guanine-nucleotide-exchange factor that mediates signalling of membrane ruffling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411262200

NMR structure and mutagenesis of the N-terminal Dbl homology domain of the nucleotide exchange factor Trio

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411262200

Structural basis for discrimination of 3-phosphoinositides by pleckstrin homology domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411262200

PIP(2)-PDZ domain binding controls the association of syntenin with the plasma membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411262200

21 January 2018

Identifiers

DOI

10.1074/JBC.M411262200

1 reference

1 August 2017

1 reference

PubMed ID

15545267