Induction of rac-guanine nucleotide exchange activity of Ras-GRF1/CDC25(Mm) following phosphorylation by the nonreceptor tyrosine kinase Src. (Q40899387)

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English	Induction of rac-guanine nucleotide exchange activity of Ras-GRF1/CDC25(Mm) following phosphorylation by the nonreceptor tyrosine kinase Src.	scientific article

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

24 September 2017

Induction of rac-guanine nucleotide exchange activity of Ras-GRF1/CDC25(Mm) following phosphorylation by the nonreceptor tyrosine kinase Src. (English)

1 reference

Europe PubMed Central

PubMed publication ID

24 September 2017

phosphorylation

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author name string

Kiyono M

1

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Europe PubMed Central

PubMed publication ID

24 September 2017

Kaziro Y

2

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Europe PubMed Central

PubMed publication ID

24 September 2017

Satoh T

3

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Europe PubMed Central

PubMed publication ID

24 September 2017

language of work or name

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publication date

1 February 2000

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Europe PubMed Central

PubMed publication ID

24 September 2017

Journal of Biological Chemistry

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Europe PubMed Central

PubMed publication ID

24 September 2017

275

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Europe PubMed Central

PubMed publication ID

24 September 2017

8

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Europe PubMed Central

PubMed publication ID

24 September 2017

5441-5446

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Europe PubMed Central

PubMed publication ID

24 September 2017

Identification of murine homologues of the Drosophila son of sevenless gene: potential activators of ras

1 reference

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Human Sos1: a guanine nucleotide exchange factor for Ras that binds to GRB2

1 reference

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Molecular cloning of cDNAs encoding a guanine-nucleotide-releasing factor for Ras p21

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Identification of a mammalian gene structurally and functionally related to the CDC25 gene of Saccharomyces cerevisiae

1 reference

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Cloning and characterization of Ras-GRF2, a novel guanine nucleotide exchange factor for Ras

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RasGRP, a Ras guanyl nucleotide- releasing protein with calcium- and diacylglycerol-binding motifs

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Regulation of RasGRP via a phorbol ester-responsive C1 domain.

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How receptor tyrosine kinases activate Ras.

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Calcium activation of Ras mediated by neuronal exchange factor Ras-GRF.

1 reference

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Ras-specific exchange factor GRF: oligomerization through its Dbl homology domain and calcium-dependent activation of Raf

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Phosphorylation-dependent activation of the Ras-GRF/CDC25Mm exchange factor by muscarinic receptors and G-protein beta gamma subunits

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Activation of the Ras-GRF/CDC25Mm exchange factor by lysophosphatidic acid

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A role for the Ras signalling pathway in synaptic transmission and long-term memory

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Rho GTPases and signaling networks

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Rho GTPases and the actin cytoskeleton

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Coupling of Ras and Rac guanosine triphosphatases through the Ras exchanger Sos.

1 reference

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21 January 2018

G protein beta gamma subunit-dependent Rac-guanine nucleotide exchange activity of Ras-GRF1/CDC25(Mm)

1 reference

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The exchange factor Ras-GRF2 activates Ras-dependent and Rac-dependent mitogen-activated protein kinase pathways

1 reference

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Tyrosine phosphorylation of ACK in response to temperature shift-down, hyperosmotic shock, and epidermal growth factor stimulation

1 reference

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G protein beta gamma subunit activates Ras, Raf, and MAP kinase in HEK 293 cells

1 reference

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Platelet-derived growth factor receptor mediates activation of ras through different signaling pathways in different cell types

1 reference

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Association between the PDGF receptor and members of the src family of tyrosine kinases

1 reference

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A role for Pyk2 and Src in linking G-protein-coupled receptors with MAP kinase activation

1 reference

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Role of c-Src tyrosine kinase in G protein-coupled receptor- and Gbetagamma subunit-mediated activation of mitogen-activated protein kinases

1 reference

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Bombesin, bradykinin, vasopressin, and phorbol esters rapidly and transiently activate Src family tyrosine kinases in Swiss 3T3 cells. Dissociation from tyrosine phosphorylation of p125 focal adhesion kinase

1 reference

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Gbetagamma subunits mediate Src-dependent phosphorylation of the epidermal growth factor receptor. A scaffold for G protein-coupled receptor-mediated Ras activation

1 reference

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The Src family tyrosine kinase is involved in Rho-dependent activation of c-Jun N-terminal kinase by Galpha12.

1 reference

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21 January 2018

G protein beta gamma subunits stimulate phosphorylation of Shc adapter protein

1 reference

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Receptor-tyrosine-kinase- and Gβγ-mediated MAP kinase activation by a common signalling pathway

1 reference

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The Btk subfamily of cytoplasmic tyrosine kinases: structure, regulation and function

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Activation of Tsk and Btk tyrosine kinases by G protein beta gamma subunits

1 reference

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Phosphotyrosine-dependent activation of Rac-1 GDP/GTP exchange by the vav proto-oncogene product

1 reference

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Lck regulates Vav activation of members of the Rho family of GTPases

1 reference

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Role of substrates and products of PI 3-kinase in regulating activation of Rac-related guanosine triphosphatases by Vav

1 reference

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21 January 2018

The G beta gamma sensitivity of a PI3K is dependent upon a tightly associated adaptor, p101

1 reference

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Cytoskeletal reorganization by G protein-coupled receptors is dependent on phosphoinositide 3-kinase gamma, a Rac guanosine exchange factor, and Rac.

1 reference

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21 January 2018

Membrane targeting of the nucleotide exchange factor Sos is sufficient for activating the Ras signaling pathway.

1 reference

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Membrane-targeting potentiates guanine nucleotide exchange factor CDC25 and SOS1 activation of Ras transforming activity

1 reference

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Signal transduction in T lymphocytes using a conditional allele of Sos

1 reference

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Lysophosphatidic acid induces threonine phosphorylation of Tiam1 in Swiss 3T3 fibroblasts via activation of protein kinase C.

1 reference

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Ca2+/calmodulin-dependent protein kinase II regulates Tiam1 by reversible protein phosphorylation

1 reference

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Direct stimulation of the guanine nucleotide exchange activity of p115 RhoGEF by Galpha13

1 reference

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p115 RhoGEF, a GTPase activating protein for Galpha12 and Galpha13

1 reference

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Guanine nucleotide exchange factor GEF115 specifically mediates activation of Rho and serum response factor by the G protein alpha subunit Galpha13

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A novel PDZ domain containing guanine nucleotide exchange factor links heterotrimeric G proteins to Rho

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A novel regulator of p21-activated kinases

1 reference

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PAK kinases are directly coupled to the PIX family of nucleotide exchange factors

1 reference

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PAK promotes morphological changes by acting upstream of Rac.

1 reference

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Signaling from G protein-coupled receptors to c-Jun kinase involves beta gamma subunits of heterotrimeric G proteins acting on a Ras and Rac1-dependent pathway

1 reference

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Pheromone signalling in Saccharomyces cerevisiae requires the small GTP-binding protein Cdc42p and its activator CDC24.

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A GTP-exchange factor required for cell orientation.

1 reference

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Association of the proto-oncogene product dbl with G protein betagamma subunits

1 reference

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Angiotensin II Controls p21 Activity via pp60

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Studies on ras proteins. Catalytic properties of normal and activated ras proteins purified in the absence of protein denaturants

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Involvement of protein kinase C and Src family tyrosine kinase in Galphaq/11-induced activation of c-Jun N-terminal kinase and p38 mitogen-activated protein kinase

1 reference

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Phosphoinositide 3-kinase gamma is a mediator of Gbetagamma-dependent Jun kinase activation

1 reference

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21 January 2018

Identifiers

10.1074/JBC.275.8.5441

1 reference

Europe PubMed Central

PubMed publication ID

24 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

24 September 2017

ResearchGate publication ID

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