A recurrent germline PAX5 mutation confers susceptibility to pre-B cell acute lymphoblastic leukemia (Q34369388)

1 August 2017

A recurrent germline PAX5 mutation confers susceptibility to pre-B cell acute lymphoblastic leukemia (English)

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1 August 2017

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lymphoblastic leukemia

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66

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1 August 2017

Georgia Chenevix-Trench

46

Georgia Chenevix-Trench

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Mary-Claire King

55

Mary-Claire King

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Cornelius Miething

6

Cornelius Miething

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Kasmintan A Schrader

Kasmintan A Schrader

2

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Deepa Bhojwani

Deepa Bhojwani

21

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Marshall Horwitz

Marshall S Horwitz

68

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Peter G Maslak

Peter Maslak

23

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Rajmohan Murali

Rajmohan Murali

30

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Hamish S. Scott

Hamish S Scott

61

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Charles G. Mullighan

Charles G Mullighan

69

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Katherine L Nathanson

Katherine L Nathanson

60

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Paul Meyers

Paul Meyers

20

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David S Ziegler

David S Ziegler

43

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Robert J Klein

Robert J Klein

10

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Vijai Joseph

5

Joseph Vijai

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1 August 2017

70

Kenneth Offit

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1 August 2017

62

Mark Daly

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41

David Wheeler

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57

Ross L Levine

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29

Marina Corines

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Sohela Shah

1

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Esmé Waanders

3

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1 August 2017

Andrew E Timms

4

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1 August 2017

Cornelius Miething

6

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1 August 2017

Jeremy Wechsler

7

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1 August 2017

Jun Yang

8

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1 August 2017

James Hayes

9

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Jinghui Zhang

11

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Lei Wei

12

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Gang Wu

13

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1 August 2017

Michael Rusch

14

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1 August 2017

Panduka Nagahawatte

15

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1 August 2017

Jing Ma

16

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1 August 2017

Shann-Ching Chen

17

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1 August 2017

Guangchun Song

18

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1 August 2017

Jinjun Cheng

19

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1 August 2017

Suresh Jhanwar

22

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1 August 2017

Martin Fleisher

24

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1 August 2017

Jason Littman

25

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1 August 2017

Lily Offit

26

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1 August 2017

Rohini Rau-Murthy

27

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1 August 2017

Megan Harlan Fleischut

28

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1 August 2017

Xiaoni Gao

31

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1 August 2017

Christopher Manschreck

32

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1 August 2017

Thomas Kitzing

33

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1 August 2017

Vundavalli V Murty

34

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1 August 2017

Susana Raimondi

35

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1 August 2017

Roland P Kuiper

36

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1 August 2017

Annet Simons

37

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1 August 2017

Joshua D Schiffman

38

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1 August 2017

Kenan Onel

39

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1 August 2017

Sharon E Plon

40

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1 August 2017

Deborah Ritter

42

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1 August 2017

Kathy Tucker

44

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1 August 2017

Rosemary Sutton

45

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1 August 2017

Jun Li

47

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1 August 2017

David G Huntsman

48

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1 August 2017

Samantha Hansford

49

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1 August 2017

Janine Senz

50

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1 August 2017

Thomas Walsh

51

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1 August 2017

Ming Lee

52

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1 August 2017

Christopher N Hahn

53

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1 August 2017

Kathryn Roberts

54

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1 August 2017

Sarah M Lo

56

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1 August 2017

Agnes Viale

58

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1 August 2017

Nicholas D Socci

59

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1 August 2017

Steven M Lipkin

63

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1 August 2017

Scott W Lowe

64

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1 August 2017

James R Downing

65

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1 August 2017

John T Sandlund

67

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1 August 2017

language of work or name

English

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publication date

8 September 2013

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1 August 2017

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1 August 2017

45

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1226-1231

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1 August 2017

10

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https://scigraph.springernature.com/pub.10.1038/ng.2754

1 August 2017

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cites work

The genomic landscape of hypodiploid acute lymphoblastic leukemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3919799

Identification of TP53 as an acute lymphocytic leukemia susceptibility gene through exome sequencing

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3919799

The B-cell identity factor Pax5 regulates distinct transcriptional programmes in early and late B lymphopoiesis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3919799

The genetic basis of early T-cell precursor acute lymphoblastic leukaemia

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3919799

Key pathways are frequently mutated in high-risk childhood acute lymphoblastic leukemia: a report from the Children's Oncology Group

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3919799

A framework for variation discovery and genotyping using next-generation DNA sequencing data

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3919799

The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3919799

Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3919799

Fast and accurate short read alignment with Burrows-Wheeler transform

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3919799

Deletion of IKZF1 and prognosis in acute lymphoblastic leukemia

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3919799

Global genomic characterization of acute lymphoblastic leukemia

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3919799

Reference alignment of SNP microarray signals for copy number analysis of tumors

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3919799

Conversion of mature B cells into T cells by dedifferentiation to uncommitted progenitors

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3919799

Genome-wide analysis of genetic alterations in acute lymphoblastic leukaemia

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3919799

A faster circular binary segmentation algorithm for the analysis of array CGH data

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3919799

Linear models and empirical bayes methods for assessing differential expression in microarray experiments

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3919799

Adjusting batch effects in microarray expression data using empirical Bayes methods

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3919799

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3919799

Circular binary segmentation for the analysis of array-based DNA copy number data

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3919799

Bioconductor: open software development for computational biology and bioinformatics

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3919799

dChipSNP: significance curve and clustering of SNP-array-based loss-of-heterozygosity data

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3919799

Groucho suppresses Pax2 transactivation by inhibition of JNK-mediated phosphorylation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3919799

Requirements for selective recruitment of Ets proteins and activation of mb-1/Ig-alpha gene transcription by Pax-5 (BSAP).

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3919799

Exploration, normalization, and summaries of high density oligonucleotide array probe level data

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3919799

Activation of the early B-cell-specific mb-1 (Ig-alpha) gene by Pax-5 is dependent on an unmethylated Ets binding site.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3919799

Transcriptional repression by Pax5 (BSAP) through interaction with corepressors of the Groucho family

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3919799

Commitment to the B-lymphoid lineage depends on the transcription factor Pax5

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3919799

DNA-binding and transactivation properties of Pax-6: three amino acids in the paired domain are responsible for the different sequence recognition of Pax-6 and BSAP (Pax-5).

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3919799

Immunochemical studies on mouse myeloma proteins with specificity for dextran or for levan

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3919799

Regulation of membrane IgM expression in secretory B cells: translational and post-translational events

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3919799

Molecular components of the B-cell antigen receptor complex of the IgM class.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3919799

High-resolution genomic profiling of childhood ALL reveals novel recurrent genetic lesions affecting pathways involved in lymphocyte differentiation and cell cycle progression.

6 July 2018

1 reference

Acute lymphoblastic leukaemia

21 January 2018

1 reference

Incidence and diversity of PAX5 fusion genes in childhood acute lymphoblastic leukemia.

21 January 2018

1 reference

Pax5/BSAP maintains the identity of B cells in late B lymphopoiesis.

21 January 2018

1 reference

Identification of Pax5 target genes in early B cell differentiation.

21 January 2018

1 reference

Gene repression by Pax5 in B cells is essential for blood cell homeostasis and is reversed in plasma cells.

21 January 2018

1 reference

Transcription factor Pax5 activates the chromatin of key genes involved in B cell signaling, adhesion, migration, and immune function.

21 January 2018

1 reference

Single nucleotide polymorphism microarray analysis of genetic alterations in cancer

21 January 2018

1 reference

BCR–ABL1 lymphoblastic leukaemia is characterized by the deletion of Ikaros

21 January 2018

1 reference

Risks among siblings and twins for childhood acute lymphoid leukaemia: results from the Swedish Family-Cancer Database

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24013638

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NG.2754

1 reference

Dimensions Publication ID

1 August 2017

0 references

1 reference

1 August 2017

1 reference