p38alpha mitogen-activated protein kinase plays a critical role in cardiomyocyte survival but not in cardiac hypertrophic growth in response to pressure overload. (Q34372422)

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English	p38alpha mitogen-activated protein kinase plays a critical role in cardiomyocyte survival but not in cardiac hypertrophic growth in response to pressure overload.	scientific article

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5 January 2020

p38alpha mitogen-activated protein kinase plays a critical role in cardiomyocyte survival but not in cardiac hypertrophic growth in response to pressure overload (English)

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5 January 2020

Jun-ichi Miyazaki

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5 January 2020

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Kazuhiko Nishida

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5 January 2020

Osamu Yamaguchi

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Shinichi Hirotani

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Shungo Hikoso

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5 January 2020

Yoshiharu Higuchi

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Tetsuya Watanabe

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5 January 2020

Toshihiro Takeda

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Soh Osuka

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Takashi Morita

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5 January 2020

Gen Kondoh

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5 January 2020

Yoshihiro Uno

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5 January 2020

Kazunori Kashiwase

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5 January 2020

Masayuki Taniike

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5 January 2020

Atsuko Nakai

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5 January 2020

Yasushi Matsumura

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5 January 2020

Tatsuhiko Sudo

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5 January 2020

Kenichi Hongo

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5 January 2020

Yoichiro Kusakari

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5 January 2020

Satoshi Kurihara

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5 January 2020

Kenneth R Chien

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5 January 2020

Junji Takeda

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Masatsugu Hori

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Kinya Otsu

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1 December 2004

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5 January 2020

Molecular and Cellular Biology

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5 January 2020

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5 January 2020

10611-10620

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5 January 2020

Targeted inhibition of p38 mitogen-activated protein kinase antagonizes cardiac injury and cell death following ischemia-reperfusion in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=533965

6 July 2018

Targeted deletion of apoptosis signal-regulating kinase 1 attenuates left ventricular remodeling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=533965

6 July 2018

Targeted inhibition of p38 MAPK promotes hypertrophic cardiomyopathy through upregulation of calcineurin-NFAT signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=533965

6 July 2018

The role of the Grb2-p38 MAPK signaling pathway in cardiac hypertrophy and fibrosis

1 reference

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6 July 2018

The suppressor of cytokine signaling-1 (SOCS1) is a novel therapeutic target for enterovirus-induced cardiac injury

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6 July 2018

Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases

1 reference

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6 July 2018

The in vivo role of p38 MAP kinases in cardiac remodeling and restrictive cardiomyopathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=533965

6 July 2018

Requirement for p38alpha in erythropoietin expression: a role for stress kinases in erythropoiesis

1 reference

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6 July 2018

p38 protects human melanoma cells from UV-induced apoptosis through down-regulation of NF-kappaB activity and Fas expression

1 reference

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6 July 2018

Two distinct forms of MAPKAP kinase-2 in adult cardiac ventricular myocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=533965

6 July 2018

alpha B-crystallin gene induction and phosphorylation by MKK6-activated p38. A potential role for alpha B-crystallin as a target of the p38 branch of the cardiac stress response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=533965

6 July 2018

Loss of a gp130 cardiac muscle cell survival pathway is a critical event in the onset of heart failure during biomechanical stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=533965

6 July 2018

Inhibition of p38 mitogen-activated protein kinase decreases cardiomyocyte apoptosis and improves cardiac function after myocardial ischemia and reperfusion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=533965

6 July 2018

An inhibitor of p38 mitogen-activated protein kinase protects neonatal cardiac myocytes from ischemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=533965

6 July 2018

Role of the stress-activated protein kinases in endothelin-induced cardiomyocyte hypertrophy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=533965

6 July 2018

Opposing effects of Jun kinase and p38 mitogen-activated protein kinases on cardiomyocyte hypertrophy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=533965

6 July 2018

Ventricular muscle-restricted targeting of the RXRalpha gene reveals a non-cell-autonomous requirement in cardiac chamber morphogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=533965

6 July 2018

Cardiac muscle cell hypertrophy and apoptosis induced by distinct members of the p38 mitogen-activated protein kinase family

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=533965

6 July 2018

A role for the p38 mitogen-activated protein kinase pathway in myocardial cell growth, sarcomeric organization, and cardiac-specific gene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=533965

6 July 2018

A transgenic mouse line that retains Cre recombinase activity in mature oocytes irrespective of the cre transgene transmission.

1 reference

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6 July 2018

Novel homologues of CSBP/p38 MAP kinase: activation, substrate specificity and sensitivity to inhibition by pyridinyl imidazoles

1 reference

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6 July 2018

Gene recombination in postmitotic cells. Targeted expression of Cre recombinase provokes cardiac-restricted, site-specific rearrangement in adult ventricular muscle in vivo.

1 reference

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6 July 2018

FGF and stress regulate CREB and ATF-1 via a pathway involving p38 MAP kinase and MAPKAP kinase-2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=533965

6 July 2018

Efficient in vivo manipulation of mouse genomic sequences at the zygote stage

1 reference

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6 July 2018

Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death

1 reference

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6 July 2018

A protein kinase involved in the regulation of inflammatory cytokine biosynthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=533965

6 July 2018

A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=533965

6 July 2018

Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=533965

6 July 2018

Segregation of atrial-specific and inducible expression of an atrial natriuretic factor transgene in an in vivo murine model of cardiac hypertrophy

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6 July 2018

Disruption of a single copy of the p38alpha MAP kinase gene leads to cardioprotection against ischemia-reperfusion.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=533965

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The antioxidant N-2-mercaptopropionyl glycine attenuates left ventricular hypertrophy in in vivo murine pressure-overload model

1 reference

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27 October 2018

Stimulation of the p38 mitogen-activated protein kinase pathway in neonatal rat ventricular myocytes by the G protein-coupled receptor agonists, endothelin-1 and phenylephrine: a role in cardiac myocyte hypertrophy?

1 reference

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27 October 2018

Induction of apoptosis by SB202190 through inhibition of p38beta mitogen-activated protein kinase

1 reference

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27 October 2018

p38 mitogen-activated protein kinase pathway protects adult rat ventricular myocytes against beta -adrenergic receptor-stimulated apoptosis. Evidence for Gi-dependent activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/15572667

12 December 2020

based on heuristic

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Morphological and molecular characterization of adult cardiomyocyte apoptosis during hypoxia and reoxygenation

1 reference

https://pubmed.ncbi.nlm.nih.gov/15572667

12 December 2020

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inferred from PubMed ID database lookup

Essential role of p38alpha MAP kinase in placental but not embryonic cardiovascular development

1 reference

https://pubmed.ncbi.nlm.nih.gov/15572667

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cardiac-specific overexpression of a high Ca2+ affinity mutant of SERCA2a attenuates in vivo pressure overload cardiac hypertrophy

1 reference

https://pubmed.ncbi.nlm.nih.gov/15572667

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Another mechanism for the defect in type III collagen accumulation in Ehlers-Danlos syndrome type IV: increased intracellular degradation of the procollagen

1 reference

https://pubmed.ncbi.nlm.nih.gov/15572667

12 December 2020

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Identifiers

10.1128/MCB.24.24.10611-10620.2004

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5 January 2020

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5 January 2020

PubMed publication ID

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5 January 2020

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