Genomic and bioinformatic profiling of mutational neoepitopes reveals new rules to predict anticancer immunogenicity (Q34375163)

1 August 2017

Genomic and bioinformatic profiling of mutational neoepitopes reveals new rules to predict anticancer immunogenicity (English)

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1 August 2017

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10

Alessandro Sette

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1 August 2017

Jorge Duitama

2

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Ion I. Mandoiu

object named as

Ion I Mandoiu

12

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John Sidney

9

object named as

John Sidney

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1 August 2017

11

Brian M Baker

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1 August 2017

5

Steven A Corcelli

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1 August 2017

Fei Duan

1

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1 August 2017

Sahar Al Seesi

3

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1 August 2017

Cory M Ayres

4

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1 August 2017

Arpita P Pawashe

6

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1 August 2017

Tatiana Blanchard

7

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1 August 2017

David McMahon

8

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1 August 2017

Pramod K Srivastava

13

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1 August 2017

language of work or name

English

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publication date

22 September 2014

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Journal of Experimental Medicine

1 August 2017

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1 August 2017

211

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1 August 2017

11

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1 August 2017

2231-2248

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HLA-binding properties of tumor neoepitopes in humans

1 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4203949

Systematic identification of personal tumor-specific neoantigens in chronic lymphocytic leukemia

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4203949

Protein structure modeling with MODELLER.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4203949

Mutated PPP1R3B is recognized by T cells used to treat a melanoma patient who experienced a durable complete tumor regression.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4203949

Accurate structure prediction of peptide-MHC complexes for identifying highly immunogenic antigens

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4203949

6 July 2018

Cancer genome landscapes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4203949

Measurement of MHC/peptide interactions by gel filtration or monoclonal antibody capture

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4203949

Area under the curve as a tool to measure kinetics of tumor growth in experimental animals.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4203949

Routine Microsecond Molecular Dynamics Simulations with AMBER on GPUs. 1. Generalized Born

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4203949

Towards accurate detection and genotyping of expressed variants from whole transcriptome sequencing data

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4203949

RNA-seq analysis of prostate cancer in the Chinese population identifies recurrent gene fusions, cancer-associated long noncoding RNAs and aberrant alternative splicings

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4203949

Cancer exome analysis reveals a T-cell-dependent mechanism of cancer immunoediting

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4203949

Exploiting the mutanome for tumor vaccination.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4203949

Loss of T Cell Antigen Recognition Arising from Changes in Peptide and Major Histocompatibility Complex Protein Flexibility: IMPLICATIONS FOR VACCINE DESIGN

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4203949

Mouse genomic variation and its effect on phenotypes and gene regulation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4203949

Exome sequencing identifies GRIN2A as frequently mutated in melanoma

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4203949

Analyzing and minimizing PCR amplification bias in Illumina sequencing libraries

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4203949

Antigen spreading contributes to MAGE vaccination-induced regression of melanoma metastases

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4203949

Anti-CTLA-4 antibody therapy: immune monitoring during clinical development of a novel immunotherapy

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4203949

The Sequence Alignment/Map format and SAMtools

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4203949

Immune rejection of mouse tumors expressing mutated self.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4203949

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4203949

"It is the antigen(s), stupid" and other lessons from over a decade of vaccitherapy of human cancer.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4203949

Identification of host proteins required for HIV infection through a functional genomic screen

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4203949

Structures of MART-126/27–35 Peptide/HLA-A2 Complexes Reveal a Remarkable Disconnect between Antigen Structural Homology and T Cell Recognition

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4203949

Natural MHC class I polymorphism controls the pathway of peptide dissociation from HLA-B27 complexes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4203949

A quantitative analysis of the variables affecting the repertoire of T cell specificities recognized after vaccinia virus infection

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4203949

The response of autologous T cells to a human melanoma is dominated by mutated neoantigens

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4203949

The Amber biomolecular simulation programs

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4203949

Increased immunogenicity of an anchor-modified tumor-associated antigen is due to the enhanced stability of the peptide/MHC complex: implications for vaccine design

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4203949

The immunobiology of cancer immunosurveillance and immunoediting

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4203949

CTLA-4: new insights into its biological function and use in tumor immunotherapy

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4203949

Class I major histocompatibility complex anchor substitutions alter the conformation of T cell receptor contacts

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4203949

Four A6-TCR/peptide/HLA-A2 structures that generate very different T cell signals are nearly identical

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4203949

Mutated mitogen-activated protein kinase: a tumor rejection antigen of mouse sarcoma

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4203949

Analysis of cytotoxic T cell responses to dominant and subdominant epitopes during acute and chronic lymphocytic choriomeningitis virus infection

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4203949

Peptide-binding heat shock proteins in the endoplasmic reticulum: role in immune response to cancer and in antigen presentation.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4203949

The concept of immunological surveillance

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4203949

snpTree--a web-server to identify and construct SNP trees from whole genome sequence data

6 July 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20141308

Modeling mutations in protein structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20141308

Two complementary methods for predicting peptides binding major histocompatibility complex molecules.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20141308

Accurate approximation method for prediction of class I MHC affinities for peptides of length 8, 10 and 11 using prediction tools trained on 9mers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20141308

Structural definition of the H-2Kd peptide-binding motif

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20141308

Dynamical characterization of two differentially disease associated MHC class I proteins in complex with viral and self-peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20141308

Epitope landscape in breast and colorectal cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20141308

Modeling the repertoire of true tumor-specific MHC I epitopes in a human tumor

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20141308

Tumor exome analysis reveals neoantigen-specific T-cell reactivity in an ipilimumab-responsive melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20141308

Identification of a tumor-associated contact-dependent activity which reversibly downregulates cytolytic function of CD8+ T cells

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4203949

Complex assembly, crystallization and preliminary X-ray crystallographic studies of MHC H-2Kd complexed with an HBV-core nonapeptide

27 October 2018

1 reference

12 December 2020

Eradication of established tumors by CD8+ T cell adoptive immunotherapy

1 reference

12 December 2020

Analysis of the frequencies of HLA-A, B, and C alleles and haplotypes in the five major ethnic groups of the United States reveals high levels of diversity in these loci and contrasting distribution patterns in these populations

1 reference

12 December 2020

Epitope spreading upon P815 tumor rejection triggered by vaccination with the single class I MHC-restricted peptide P1A

1 reference

12 December 2020

Identifiers

DOI

10.1084/JEM.20141308

1 reference

1 August 2017

1 reference

1 August 2017

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