Gene targeting reveals a role for the glutamate receptors mGluR5 and GluR2 in learning and memory (Q34375846)

1 August 2017

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title

Gene targeting reveals a role for the glutamate receptors mGluR5 and GluR2 in learning and memory (English)

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1 August 2017

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Jia Z

1

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1 August 2017

Lu YM

series ordinal

2

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1 August 2017

Agopyan N

series ordinal

3

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1 August 2017

Roder J

series ordinal

4

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1 August 2017

language of work or name

English

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publication date

1 August 2001

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1 August 2017

Physiology & Behavior

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1 August 2017

73

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1 August 2017

5

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1 August 2017

793-802

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PKC gamma mutant mice exhibit mild deficits in spatial and contextual learning.

1 August 2017

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https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

Activation of NMDA receptors reverses desensitization of mGluR5 in native and recombinant systems.

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

Channel gating kinetics and synaptic efficacy: a hypothesis for expression of long-term potentiation

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

Impairment of spatial but not contextual memory in CaMKII mutant mice with a selective loss of hippocampal LTP in the range of the theta frequency.

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

Distinct components of spatial learning revealed by prior training and NMDA receptor blockade.

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

Regulatory phosphorylation of AMPA-type glutamate receptors by CaM-KII during long-term potentiation

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

Modulation of AMPA receptor unitary conductance by synaptic activity

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https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

(+/-)-Alpha-methyl-4-carboxyphenylglycine, a metabotropic glutamate receptor blocker, impairs retention of an inhibitory avoidance task in rats when infused into the basolateral nucleus of the amygdala

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

The saturation debate.

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

A synaptic model of memory: long-term potentiation in the hippocampus

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

Regulation of hippocampal transmitter release during development and long-term potentiation.

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

A molecular switch activated by metabotropic glutamate receptors regulates induction of long-term potentiation.

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

Roles of metabotropic glutamate receptors in LTP and LTD in the hippocampus

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

Deficient long-term memory in mice with a targeted mutation of the cAMP-responsive element-binding protein.

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

Regulation of GluR2 promoter activity by neurotrophic factors via a neuron-restrictive silencer element

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

Early-onset epilepsy and postnatal lethality associated with an editing-deficient GluR-B allele in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

Divalent ion permeability of AMPA receptor channels is dominated by the edited form of a single subunit

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

Calcium-permeable AMPA-kainate receptors in fusiform cerebellar glial cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

Induction of LTD by activation of group I mGluR in the dentate gyrus in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

A new form of long-term depression in the perirhinal cortex.

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

Motor deficit and impairment of synaptic plasticity in mice lacking mGluR1.

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

Genetics of mouse behavior: interactions with laboratory environment.

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

The NMDA receptor antagonist D-2-amino-5-phosphonopentanoate (D-AP5) impairs spatial learning and LTP in vivo at intracerebral concentrations comparable to those that block LTP in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

Structural determinants of barium permeation and rectification in non-NMDA glutamate receptor channels

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

Inactivation of NMDA receptors by direct interaction of calmodulin with the NR1 subunit

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

Complex interactions between mGluRs, intracellular Ca2+ stores and ion channels in neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

Targeted disruption of NMDA receptor 1 gene abolishes NMDA response and results in neonatal death

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

Facilitation of NMDAR-independent LTP and spatial learning in mutant mice lacking ryanodine receptor type 3.

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

Relative abundance of subunit mRNAs determines gating and Ca2+ permeability of AMPA receptors in principal neurons and interneurons in rat CNS

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

Gene-targeting studies of mammalian behavior: is it the mutation or the background genotype?

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

Multiple behavioral anomalies in GluR2 mutant mice exhibiting enhanced LTP.

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

Inducible gene expression in the nervous system of transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

Impaired long-term potentiation, spatial learning, and hippocampal development in fyn mutant mice

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

Enhancement of the glutamate response by cAMP-dependent protein kinase in hippocampal neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

Synaptic strengthening through activation of Ca2+-permeable AMPA receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

G-protein-independent signaling mediated by metabotropic glutamate receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

Complex behavioral strategy and reversal learning in the water maze without NMDA receptor-dependent long-term potentiation.

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

Cloned glutamate receptors

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https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

Genome-wide, large-scale production of mutant mice by ENU mutagenesis.

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

A genetic test of the effects of mutations in PKA on mossy fiber LTP and its relation to spatial and contextual learning.

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

CAKbeta/Pyk2 kinase is a signaling link for induction of long-term potentiation in CA1 hippocampus

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

Formation of temporal memory requires NMDA receptors within CA1 pyramidal neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

Identification of a site in glutamate receptor subunits that controls calcium permeability

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

mGluR1 in cerebellar Purkinje cells essential for long-term depression, synapse elimination, and motor coordination

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

The influence of glutamate receptor 2 expression on excitotoxicity in Glur2 null mutant mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

Different hippocampal molecular requirements for short- and long-term retrieval of one-trial avoidance learning.

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

Enhanced LTP in mice deficient in the AMPA receptor GluR2.

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

Induction of LTD in the adult hippocampus by the synaptic activation of AMPA/kainate and metabotropic glutamate receptors.

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

Ca(2+)-permeable AMPA and NMDA receptor channels in basket cells of rat hippocampal dentate gyrus

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

Rescuing impairment of long-term potentiation in fyn-deficient mice by introducing Fyn transgene

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

The CaM kinase II hypothesis for the storage of synaptic memory

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

Relating hippocampal circuitry to function: recall of memory sequences by reciprocal dentate-CA3 interactions

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

Synaptic activity at calcium-permeable AMPA receptors induces a switch in receptor subtype

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

G-protein-coupled receptors act via protein kinase C and Src to regulate NMDA receptors.

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

Endogenous Zn2+ is required for the induction of long-term potentiation at rat hippocampal mossy fiber-CA3 synapses

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

Calcineurin-mediated LTD of GABAergic inhibition underlies the increased excitability of CA1 neurons associated with LTP.

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

Src activation in the induction of long-term potentiation in CA1 hippocampal neurons.

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

Mice lacking metabotropic glutamate receptor 5 show impaired learning and reduced CA1 long-term potentiation (LTP) but normal CA3 LTP

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

Role of AMPA receptor cycling in synaptic transmission and plasticity

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

Hippocampal LTD expression involves a pool of AMPARs regulated by the NSF-GluR2 interaction

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

Use-dependent AMPA receptor block in mice lacking GluR2 suggests postsynaptic site for LTP expression

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

Long-term potentiation--a decade of progress?

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https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

Postsynaptic calcium is sufficient for potentiation of hippocampal synaptic transmission.

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

An essential role for postsynaptic calmodulin and protein kinase activity in long-term potentiation.

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

Temporal limits on the rise in postsynaptic calcium required for the induction of long-term potentiation

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

Rapid Dendritic Morphogenesis in CA1 Hippocampal Dendrites Induced by Synaptic Activity

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

5-HT1B receptor knock-out mice exhibit increased exploratory activity and enhanced spatial memory performance in the Morris water maze.

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

Facilitation of long-term potentiation and memory in mice lacking nociceptin receptors.

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

Synaptic plasticity and memory: an evaluation of the hypothesis

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

Long-term potentiation and learning

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

Disruption of AMPA receptor GluR2 clusters following long-term depression induction in cerebellar Purkinje neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

The 3'-untranslated region of CaMKII alpha is a cis-acting signal for the localization and translation of mRNA in dendrites

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

Genetic approaches to memory storage

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

Control of memory formation through regulated expression of a CaMKII transgene

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

Training in the Morris water maze occludes the synergism between ACPD and arachidonic acid on glutamate release in synaptosomes prepared from rat hippocampus.

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

Enhanced long-term potentiation and impaired learning in mice with mutant postsynaptic density-95 protein

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

Deficits in memory and hippocampal long-term potentiation in mice with reduced calbindin D28K expression.

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

Impaired spatial learning after saturation of long-term potentiation.

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

Derivation of completely cell culture-derived mice from early-passage embryonic stem cells

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

Synergistic release of Ca2+ from IP3-sensitive stores evoked by synaptic activation of mGluRs paired with backpropagating action potentials

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

Contrasting properties of two forms of long-term potentiation in the hippocampus.

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

Surface expression of AMPA receptors in hippocampal neurons is regulated by an NSF-dependent mechanism.

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

A systematic, genome-wide, phenotype-driven mutagenesis programme for gene function studies in the mouse

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

Normal spatial learning despite regional inhibition of LTP in mice lacking Thy-1.

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

Pretraining prevents spatial learning impairment after saturation of hippocampal long-term potentiation.

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

Assessment of learning by the Morris water task and fear conditioning in inbred mouse strains and F1 hybrids: implications of genetic background for single gene mutations and quantitative trait loci analyses.

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

Differential contribution of amygdala and hippocampus to cued and contextual fear conditioning

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

Selective RNA editing and subunit assembly of native glutamate receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

Metabotropic glutamate receptors trigger homosynaptic protein synthesis to prolong long-term potentiation

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

Metabotropic glutamate receptors in spatial and nonspatial learning in rats studied by means of agonist and antagonist application.

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

Enhanced learning after genetic overexpression of a brain growth protein

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

Temporal control of the Cre recombinase in transgenic mice by a tetracycline responsive promoter

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

Reduced hippocampal LTP and spatial learning in mice lacking NMDA receptor epsilon 1 subunit

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

Can molecules explain long-term potentiation?

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

Spatial learning without NMDA receptor-dependent long-term potentiation

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

Induction of NMDA receptor-dependent long-term depression in visual cortex does not require metabotropic glutamate receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

An investigation into signal transduction mechanisms involved in DHPG-induced LTD in the CA1 region of the hippocampus

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

Deficient hippocampal long-term potentiation in alpha-calcium-calmodulin kinase II mutant mice

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

Mutant Mice and Neuroscience: Recommendations Concerning Genetic Background

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

RNA editing in brain controls a determinant of ion flow in glutamate-gated channels

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

Combined deficiencies of Src, Fyn, and Yes tyrosine kinases in mutant mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

Changes in reliability of synaptic function as a mechanism for plasticity.

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

Genetic enhancement of learning and memory in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

Subregion- and cell type-restricted gene knockout in mouse brain

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

The essential role of hippocampal CA1 NMDA receptor-dependent synaptic plasticity in spatial memory

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

Coupling of mGluR/Homer and PSD-95 complexes by the Shank family of postsynaptic density proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

AMPA receptors unbound: membrane cycling and synaptic plasticity

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

Structural determinants of ion flow through recombinant glutamate receptor channels

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

Synaptic plasticity, place cells and spatial memory: study with second generation knockouts.

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

A rise in postsynaptic Ca2+ potentiates miniature excitatory postsynaptic currents and AMPA responses in hippocampal neurons.

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

Src potentiation of NMDA receptors in hippocampal and spinal neurons is not mediated by reducing zinc inhibition

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

Spatial exploration induces a persistent reversal of long-term potentiation in rat hippocampus.

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

Intrahippocampal infusions of a metabotropic glutamate receptor antagonist block the memory of context-specific but not tone-specific conditioned fear

1 reference

https://api.crossref.org/works/10.1016%2FS0031-9384%2801%2900516-9

7 January 2021

10.1016/S0031-9384(01)00516-9

Identifiers

DOI

1 reference

1 August 2017

1 reference