Modeling first-hit functions of the t(12;21) TEL-AML1 translocation in mice (Q34375984)

1 August 2017

title

Modeling first-hit functions of the t(12;21) TEL-AML1 translocation in mice (English)

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1 August 2017

3

Mel Greaves

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1 August 2017

4

Tariq Enver

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1 August 2017

2

Masao Seto

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1 August 2017

1

Shinobu Tsuzuki

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1 August 2017

language of work or name

English

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publication date

20 May 2004

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Proceedings of the National Academy of Sciences of the United States of America

1 August 2017

published in

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1 August 2017

volume

101

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1 August 2017

issue

22

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1 August 2017

page(s)

8443-8448

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Origins of chromosome translocations in childhood leukaemia

1 August 2017

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6 July 2018

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Disruption of differentiation in human cancer: AML shows the way.

6 July 2018

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AML1-ETO inhibits maturation of multiple lymphohematopoietic lineages and induces myeloblast transformation in synergy with ICSBP deficiency

6 July 2018

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TEL-AML1, expressed from t(12;21) in human acute lymphocytic leukemia, induces acute leukemia in mice.

6 July 2018

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Hematopoietic stem cell expansion and distinct myeloid developmental abnormalities in a murine model of the AML1-ETO translocation

6 July 2018

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Core-binding factors in haematopoiesis and leukaemia

6 July 2018

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Immature CD34+CD19- progenitor/stem cells in TEL/AML1-positive acute lymphoblastic leukemia are genetically and functionally normal

6 July 2018

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Expression of a conditional AML1-ETO oncogene bypasses embryonic lethality and establishes a murine model of human t(8;21) acute myeloid leukemia

6 July 2018

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Chromosome translocations and covert leukemic clones are generated during normal fetal development

6 July 2018

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Differential surrogate light chain expression governs B-cell differentiation

6 July 2018

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The AML1-ETO fusion protein promotes the expansion of human hematopoietic stem cells

6 July 2018

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The expression of ETV6/CBFA2 (TEL/AML1) is not sufficient for the transformation of hematopoietic cell lines in vitro or the induction of hematologic disease in vivo

6 July 2018

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AML1-ETO expression is directly involved in the development of acute myeloid leukemia in the presence of additional mutations

6 July 2018

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Enforced expression of the GATA-2 transcription factor blocks normal hematopoiesis.

6 July 2018

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Analysis of TEL proteins in human leukemias

6 July 2018

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Translocations, cancer and the puzzle of specificity

6 July 2018

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Analysis of ETV6 and ETV6-AML1 proteins in acute lymphoblastic leukaemia

6 July 2018

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The t(12;21) translocation converts AML-1B from an activator to a repressor of transcription

6 July 2018

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A subpopulation of B220+ cells in murine bone marrow does not express CD19 and contains natural killer cell progenitors

6 July 2018

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Early lymphocyte expansion is severely impaired in interleukin 7 receptor-deficient mice

6 July 2018

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The t(12;21) of acute lymphoblastic leukemia results in a tel-AML1 gene fusion.

6 July 2018

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Fusion of the TEL gene on 12p13 to the AML1 gene on 21q22 in acute lymphoblastic leukemia

6 July 2018

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Long-term proliferating early pre B cell lines and clones with the potential to develop to surface Ig-positive, mitogen reactive B cells in vitro and in vivo.

6 July 2018

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Resolution and characterization of pro-B and pre-pro-B cell stages in normal mouse bone marrow

6 July 2018

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The AML1-ETO fusion gene promotes extensive self-renewal of human primary erythroid cells

6 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0402063101

Proliferative kinetics and differentiation of murine blast cell colonies in culture: evidence for variable G0 periods and constant doubling rates of early pluripotent hemopoietic progenitors

21 January 2018

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B-cell development: a comparison between mouse and man.

21 January 2018

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A critical role of λ5 protein in B cell development

21 January 2018

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Analysis of the role of AML1-ETO in leukemogenesis, using an inducible transgenic mouse model

21 January 2018

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The human (PsiL+mu-) proB complex: cell surface expression and biochemical structure of a putative transducing receptor

27 October 2018

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12 December 2020

Normal B cell precursors responsive to recombinant murine IL-7 and inhibition of IL-7 activity by transforming growth factor-beta

1 reference

12 December 2020

Functional assessment of precursors from murine bone marrow suggests a sequence of early B lineage differentiation events

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12 December 2020

Recruitment of the nuclear receptor corepressor N-CoR by the TEL moiety of the childhood leukemia-associated TEL-AML1 oncoprotein

1 reference

12 December 2020

PEBP2 and c-myb sites crucial for lambda5 core enhancer activity in pre-B cells

1 reference

12 December 2020

Cooperative function of Aml1-ETO corepressor recruitment domains in the expansion of primary bone marrow cells

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12 December 2020

TEL/AML1 fusion resulting from a cryptic t(12;21) is the most common genetic lesion in pediatric ALL and defines a subgroup of patients with an excellent prognosis

1 reference

12 December 2020

Identification of the earliest B lineage stage in mouse bone marrow

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0402063101

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1 August 2017

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1 August 2017

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