Pulling strings below the surface: hormone receptor signaling through inhibition of protein tyrosine phosphatases (Q34381500)

1 August 2017

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title

Pulling strings below the surface: hormone receptor signaling through inhibition of protein tyrosine phosphatases (English)

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1 August 2017

Espanel X

1

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1 August 2017

Wälchli S

2

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1 August 2017

Gobert RP

3

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1 August 2017

El Alama M

4

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1 August 2017

Curchod ML

5

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1 August 2017

Gullu-Isler N

6

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1 August 2017

Hooft van Huijsduijnen R

7

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1 August 2017

publication date

1 June 2001

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1 August 2017

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1 August 2017

volume

15

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1 August 2017

issue

1

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1 August 2017

page(s)

19-28

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Structure-based discovery of small molecule inhibitors targeted to protein tyrosine phosphatase 1B

1 August 2017

cites work

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12 December 2020

Mutation of the SHP-2 binding site in growth hormone (GH) receptor prolongs GH-promoted tyrosyl phosphorylation of GH receptor, JAK2, and STAT5B

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12 December 2020

Biphasic effect of vanadium salts on in vitro tumor colony growth

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12 December 2020

Activation of acute phase response factor (APRF)/Stat3 transcription factor by growth hormone.

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12 December 2020

Mapping and identification of protein-protein interactions by two-dimensional far-Western immunoblotting

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12 December 2020

RNAi of the receptor tyrosine phosphatase HmLAR2 in a single cell of an intact leech embryo leads to growth-cone collapse

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12 December 2020

Regulation of signal transducer and activator of transcription (STAT) 5b activation by the temporal pattern of growth hormone stimulation

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12 December 2020

PTPROt: an alternatively spliced and developmentally regulated B-lymphoid phosphatase that promotes G0/G1 arrest

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12 December 2020

Increased abundance of the receptor-type protein-tyrosine phosphatase LAR accounts for the elevated insulin receptor dephosphorylating activity in adipose tissue of obese human subjects

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12 December 2020

The protein tyrosine phosphatase LAR has a major impact on insulin receptor dephosphorylation

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12 December 2020

Leptin modulates the T-cell immune response and reverses starvation-induced immunosuppression

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12 December 2020

Frequent PTEN/MMAC mutations in endometrioid but not serous or mucinous epithelial ovarian tumors.

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12 December 2020

Receptor recognition by gp130 cytokines

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12 December 2020

Mechanism of inhibition of protein-tyrosine phosphatases by vanadate and pervanadate

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12 December 2020

Coordinate regulation of STAT signaling and c-fos expression by the tyrosine phosphatase SHP-2.

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12 December 2020

The receptor protein tyrosine phosphatase, PTP-RO, is upregulated during megakaryocyte differentiation and Is associated with the c-Kit receptor

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12 December 2020

Defective STAT signaling by the leptin receptor in diabetic mice

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12 December 2020

The transmembrane protein tyrosine phosphatase alpha dephosphorylates the insulin receptor in intact cells

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12 December 2020

Growth hormone-promoted tyrosyl phosphorylation of SHC proteins and SHC association with Grb2

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12 December 2020

Induction of angiopoietin and Tie receptor mRNA expression after cerebral ischemia-reperfusion

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12 December 2020

Molecular cloning and functional characterization of a novel mitogen-activated protein kinase phosphatase, MKP-4

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12 December 2020

Insulin receptor signaling is augmented by antisense inhibition of the protein tyrosine phosphatase LAR.

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12 December 2020

MKP-3, a novel cytosolic protein-tyrosine phosphatase that exemplifies a new class of mitogen-activated protein kinase phosphatase

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12 December 2020

Growth hormone induces a DNA binding factor related to the interferon-stimulated 91-kDa transcription factor

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12 December 2020

How can tumor cells escape intercellular induction of apoptosis?

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12 December 2020

Protein tyrosine phosphatase 1B interacts with the activated insulin receptor

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12 December 2020

Identification of tyrosine phosphatases that dephosphorylate the insulin receptor. A brute force approach based on "substrate-trapping" mutants

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12 December 2020

Enhancing leptin response by preventing SH2-containing phosphatase 2 interaction with Ob receptor

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12 December 2020

Dietary vanadyl(IV) sulfate inhibits chemically-induced mammary carcinogenesis

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12 December 2020

Abnormal mesoderm patterning in mouse embryos mutant for the SH2 tyrosine phosphatase Shp-2.

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12 December 2020

Pleiotrophin signals increased tyrosine phosphorylation of beta beta-catenin through inactivation of the intrinsic catalytic activity of the receptor-type protein tyrosine phosphatase beta/zeta

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12 December 2020

Development of "substrate-trapping" mutants to identify physiological substrates of protein tyrosine phosphatases

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12 December 2020

Structure, mechanism, and specificity of protein-tyrosine phosphatases

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12 December 2020

Growth-hormone signal transduction

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12 December 2020

Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN

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12 December 2020

Protein-tyrosine phosphatases: biological function, structural characteristics, and mechanism of catalysis

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12 December 2020

Impaired learning with enhanced hippocampal long-term potentiation in PTPdelta-deficient mice

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12 December 2020

Downregulation of LAR tyrosine phosphatase prevents apoptosis and augments NGF-induced neurite outgrowth

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12 December 2020

Role of PTP-1B in aortic smooth muscle cell motility and tyrosine phosphorylation of focal adhesion proteins

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12 December 2020

MetaBlasts: tracing protein tyrosine phosphatase gene family roots from Man to Drosophila melanogaster and Caenorhabditis elegans genomes.

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12 December 2020

Impaired mammary gland development and function in mice lacking LAR receptor-like tyrosine phosphatase activity.

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12 December 2020

A general purpose RNA-cleaving DNA enzyme

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12 December 2020

Specific interference with gene function by double-stranded RNA in early mouse development

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12 December 2020

The regulation of B- and T-lymphocyte activation by the transmembrane protein tyrosine phosphatase CD45.

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12 December 2020

Receptor-like protein tyrosine phosphatase alpha homodimerizes on the cell surface

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12 December 2020

Down-regulation of Fas-associated phosphatase-1 (FAP-1) in interleukin-2-activated T cells

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12 December 2020

Use of vanadate as protein-phosphotyrosine phosphatase inhibitor

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12 December 2020

Expression and catalytic activity of the tyrosine phosphatase PTP1C is severely impaired in motheaten and viable motheaten mice

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12 December 2020

Leaky vessels? Call Ang1!

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12 December 2020

The transmembrane protein tyrosine phosphatase RPTPsigma modulates signaling of the epidermal growth factor receptor in A431 cells

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12 December 2020

Isolation of angiopoietin-1, a ligand for the TIE2 receptor, by secretion-trap expression cloning

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12 December 2020

Capturing genes encoding membrane and secreted proteins important for mouse development

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12 December 2020

Homozygous deletion of the PTEN tumor suppressor gene in a subset of prostate adenocarcinomas

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12 December 2020

Expression of FAP-1 (Fas-associated phosphatase) and resistance to Fas-mediated apoptosis in T cell lines derived from human T cell leukemia virus type 1-associated myelopathy/tropical spastic paraparesis patients

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12 December 2020

Emerging issues in receptor protein tyrosine phosphatase function: lifting fog or simply shifting?

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12 December 2020

Role of leptin in the neuroendocrine response to fasting

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12 December 2020

Gathering STYX: phosphatase-like form predicts functions for unique protein-interaction domains

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12 December 2020

Signaling molecules involved in coupling growth hormone receptor to mitogen-activated protein kinase activation

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12 December 2020

Apoptosis in neural development and disease

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12 December 2020

Functional interaction of vascular endothelial-protein-tyrosine phosphatase with the angiopoietin receptor Tie-2

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12 December 2020

Signalling through the insulin receptor

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12 December 2020

Dual specificity phosphatases: a gene family for control of MAP kinase function.

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12 December 2020

Decrease in protein tyrosine phosphatase activities in vanadate-treated obese Zucker (fa/fa) rat liver

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12 December 2020

Involvement of the Src homology 2-containing tyrosine phosphatase SHP-2 in growth hormone signaling

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12 December 2020

Inactivation of the tumor suppressor PTEN/MMAC1 in advanced human prostate cancer through loss of expression

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12 December 2020

Growth-hormone-receptor and cytokine-receptor-family signaling

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12 December 2020

Suppression of metastatic potential of high-metastatic Lewis lung carcinoma cells by vanadate, an inhibitor of tyrosine phosphatase, through inhibiting cell-substrate adhesion

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12 December 2020

Hypomyelination and increased activity of voltage-gated K(+) channels in mice lacking protein tyrosine phosphatase epsilon

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12 December 2020

Transgenic mice deficient in the LAR protein-tyrosine phosphatase exhibit profound defects in glucose homeostasis.

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12 December 2020

Shp-2 tyrosine phosphatase: signaling one cell or many

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12 December 2020

Role of PI 3-kinase and SH-PTP2 in insulin action

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12 December 2020

PTEN, a unique tumor suppressor gene

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12 December 2020

Charcot-Marie-Tooth type 4B is caused by mutations in the gene encoding myotubularin-related protein-2.

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12 December 2020

Protein tyrosine phosphatase-PEST regulates focal adhesion disassembly, migration, and cytokinesis in fibroblasts

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12 December 2020

Identification of JAK2 as a growth hormone receptor-associated tyrosine kinase

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12 December 2020

Human pancreatic adenocarcinomas express Fas and Fas ligand yet are resistant to Fas-mediated apoptosis

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12 December 2020

Involvement of the SHP-1 tyrosine phosphatase in regulating B lymphocyte antigen receptor signaling, proliferation and transformation

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12 December 2020

Suppression of insulin receptor activation by overexpression of the protein-tyrosine phosphatase LAR in hepatoma cells

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12 December 2020

Interaction of SH2-containing protein tyrosine phosphatase 2 with the insulin receptor and the insulin-like growth factor-I receptor: studies of the domains involved using the yeast two-hybrid system

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12 December 2020

PTPmu regulates N-cadherin-dependent neurite outgrowth

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12 December 2020

Structural basis for inhibition of receptor protein-tyrosine phosphatase-alpha by dimerization

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12 December 2020

Dual roles for glucokinase in glucose homeostasis as determined by liver and pancreatic beta cell-specific gene knock-outs using Cre recombinase

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12 December 2020

No obvious abnormality in mice deficient in receptor protein tyrosine phosphatase beta

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12 December 2020

Dimerization of the extracellular domain of the human growth hormone receptor by a single hormone molecule

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12 December 2020

From Vanadis to Atropos: vanadium compounds as pharmacological tools in cell death signalling.

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12 December 2020

Insulin-induced tyrosine dephosphorylation of paxillin and focal adhesion kinase requires active phosphotyrosine phosphatase 1D.

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12 December 2020

Growth hormone-induced signal tranduction depends on an intact ubiquitin system

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12 December 2020

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12 December 2020

Leptin and its potential role in human obesity

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12 December 2020

Inhibition of protein tyrosine phosphatases by low-molecular-weight S-nitrosothiols and S-nitrosylated human serum albumin

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12 December 2020

Neuroendocrine dysplasia in mice lacking protein tyrosine phosphatase sigma

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12 December 2020

Molecular cloning of a novel protein‐tyrosine phosphatase SH‐PTP3 with sequence similarity to the src‐homology region 2

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12 December 2020

CD45 specifically modulates binding of Lck to a phosphopeptide encompassing the negative regulatory tyrosine of Lck.

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12 December 2020

Localization of leptin receptor mRNA splice variants in murine peripheral tissues by RT-PCR and in situ hybridization

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12 December 2020

The ubiquitin conjugation system is required for ligand-induced endocytosis and degradation of the growth hormone receptor.

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12 December 2020

Hematopoietic cell phosphatase negatively regulates erythropoietin-induced hemoglobinization in erythroleukemic SKT6 cells

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12 December 2020

Impaired bone marrow microenvironment and immune function in T cell protein tyrosine phosphatase-deficient mice

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12 December 2020

Protein tyrosine phosphatases: counting the trees in the forest

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12 December 2020

Protein-tyrosine phosphatases: structure, mechanism, and inhibitor discovery

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12 December 2020

Hematologic effects of interleukin-1 and interleukin-6.

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12 December 2020

Obesity in the new millennium

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12 December 2020

Increased insulin sensitivity and obesity resistance in mice lacking the protein tyrosine phosphatase-1B gene

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12 December 2020

2-(oxalylamino)-benzoic acid is a general, competitive inhibitor of protein-tyrosine phosphatases

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12 December 2020

Nonadipose tissue production of leptin: leptin as a novel placenta-derived hormone in humans

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12 December 2020

Mediation of growth hormone-dependent transcriptional activation by mammary gland factor/Stat 5.

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12 December 2020

Angiopoietin-1 protects the adult vasculature against plasma leakage.

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12 December 2020

LMW-PTP is a negative regulator of insulin-mediated mitotic and metabolic signalling

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12 December 2020

Skeletal muscle protein tyrosine phosphatase activity and tyrosine phosphatase 1B protein content are associated with insulin action and resistance

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12 December 2020

Interleukin-6 triggers the association of its receptor with a possible signal transducer, gp130

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12 December 2020

Leptin and the regulation of body weight in mammals

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12 December 2020

Protein-tyrosine phosphatase 1B complexes with the insulin receptor in vivo and is tyrosine-phosphorylated in the presence of insulin

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12 December 2020

Receptor tyrosine kinases and their targets

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12 December 2020

Elevated expression and activity of protein-tyrosine phosphatase 1B in skeletal muscle of insulin-resistant type II diabetic Goto-Kakizaki rats.

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12 December 2020

Evidence that the protein tyrosine phosphatase (PC12,Br7,Sl) gamma (-) isoform modulates chondrogenic patterning and growth

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12 December 2020

Growth hormone regulation of SIRP and SHP-2 tyrosyl phosphorylation and association

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12 December 2020

Vanadium salts as insulin substitutes: mechanisms of action, a scientific and therapeutic tool in diabetes mellitus research

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12 December 2020

Pleiotrophin and midkine, a family of mitogenic and angiogenic heparin-binding growth and differentiation factors

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12 December 2020

PTEN mutations in gliomas and glioneuronal tumors.

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12 December 2020

The molecular interaction of Fas and FAP-1. A tripeptide blocker of human Fas interaction with FAP-1 promotes Fas-induced apoptosis

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12 December 2020

Protein-tyrosine phosphatase-1B acts as a negative regulator of insulin signal transduction

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12 December 2020

FAP-1: a protein tyrosine phosphatase that associates with Fas

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12 December 2020

Protein tyrosine phosphatase 2 (SHP-2) moderates signaling by gp130 but is not required for the induction of acute-phase plasma protein genes in hepatic cells

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12 December 2020

The stomach is a source of leptin

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12 December 2020

Protein phosphatases and the regulation of mitogen-activated protein kinase signalling.

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12 December 2020

Dissection of protein kinase and phosphatase targeting interactions

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12 December 2020

Deficiency of SHP-1 protein-tyrosine phosphatase activity results in heightened osteoclast function and decreased bone density

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12 December 2020

Identification and expression cloning of a leptin receptor, OB-R

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12 December 2020

Alloreactivity and apoptosis in graft rejection and transplantation tolerance.

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12 December 2020

Increased energy expenditure, decreased adiposity, and tissue-specific insulin sensitivity in protein-tyrosine phosphatase 1B-deficient mice

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12 December 2020

Occludin proteolysis and increased permeability in endothelial cells through tyrosine phosphatase inhibition

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12 December 2020

Motheaten and viable motheaten mice have mutations in the haematopoietic cell phosphatase gene

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12 December 2020

Analysis of PTEN and the 10q23 region in primary prostate carcinomas

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12 December 2020

Regulation of rat growth hormone receptor gene expression

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12 December 2020

Catalytic Activation of the Phosphatase MKP-3 by ERK2 Mitogen-Activated Protein Kinase

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12 December 2020

Hematopoietic cell phosphatase associates with erythropoietin (Epo) receptor after Epo-induced receptor tyrosine phosphorylation: identification of potential binding sites

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12 December 2020

Receptor protein tyrosine phosphatase gamma, Ptp gamma, regulates hematopoietic differentiation.

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12 December 2020

Requirement of PEST domain tyrosine phosphatase PEP in B cell antigen receptor-induced growth arrest and apoptosis

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12 December 2020

Leptin receptor activation of SH2 domain containing protein tyrosine phosphatase 2 modulates Ob receptor signal transduction

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12 December 2020

Identifiers

DOI

10.1385/ENDO:15:1:019

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Dimensions Publication ID

1 August 2017

1032818698

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