Intestinal drug efflux: formulation and food effects (Q34384325)

1 August 2017

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title

Intestinal drug efflux: formulation and food effects (English)

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1 August 2017

Wagner D

1

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1 August 2017

Spahn-Langguth H

2

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1 August 2017

Hanafy A

3

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1 August 2017

Koggel A

4

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1 August 2017

Langguth P

5

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1 August 2017

language of work or name

English

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publication date

1 October 2001

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Advanced Drug Delivery Reviews

1 August 2017

published in

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1 August 2017

volume

50 Suppl 1

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1 August 2017

page(s)

S13-31

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Carrier-mediated intestinal transport of drugs

1 August 2017

cites work

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https://api.crossref.org/works/10.1016%2FS0169-409X%2801%2900183-1

7 January 2021

Drug transport in intestine, liver and kidney

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7 January 2021

Drug exsorption from blood into the gastrointestinal tract

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7 January 2021

Antibiotic efflux pumps

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7 January 2021

Structure-activity relationship of P-glycoprotein substrates and modifiers.

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7 January 2021

Substrate recognition by P-glycoprotein and the multidrug resistance-associated protein MRP1: a comparison.

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7 January 2021

The biology of the P-glycoproteins

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7 January 2021

Biochemical, cellular, and pharmacological aspects of the multidrug transporter

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7 January 2021

Structure and expression of the human MDR (P-glycoprotein) gene family

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https://api.crossref.org/works/10.1016%2FS0169-409X%2801%2900183-1

7 January 2021

Both ATP sites of human P-glycoprotein are essential but not symmetric

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2801%2900183-1

7 January 2021

Absence of the mdr1a P-Glycoprotein in mice affects tissue distribution and pharmacokinetics of dexamethasone, digoxin, and cyclosporin A.

1 reference

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7 January 2021

Overlapping substrate specificities and tissue distribution of cytochrome P450 3A and P-glycoprotein: implications for drug delivery and activity in cancer chemotherapy.

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7 January 2021

The multidrug resistance protein family.

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7 January 2021

Multidrug resistance protein 1 protects the choroid plexus epithelium and contributes to the blood-cerebrospinal fluid barrier

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https://api.crossref.org/works/10.1016%2FS0169-409X%2801%2900183-1

7 January 2021

ATP- and glutathione-dependent transport of chemotherapeutic drugs by the multidrug resistance protein MRP1.

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7 January 2021

Organic cation transporters in intestine, kidney, liver, and brain

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https://api.crossref.org/works/10.1016%2FS0169-409X%2801%2900183-1

7 January 2021

Electrogenic properties and substrate specificity of the polyspecific rat cation transporter rOCT1.

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https://api.crossref.org/works/10.1016%2FS0169-409X%2801%2900183-1

7 January 2021

A reevaluation of substrate specificity of the rat cation transporter rOCT1.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2801%2900183-1

7 January 2021

beta-lactam antibiotics as substrates for OCTN2, an organic cation/carnitine transporter

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2801%2900183-1

7 January 2021

Calcein is excreted from the intestinal mucosal cell membrane by the active transport system

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2801%2900183-1

7 January 2021

Net secretion of furosemide is subject to indomethacin inhibition, as observed in Caco-2 monolayers and excised rat jejunum

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2801%2900183-1

7 January 2021

Molecular identification and characterization of novel members of the human organic anion transporter (OATP) family

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2801%2900183-1

7 January 2021

Cloning, in vitro expression, and tissue distribution of a human prostaglandin transporter cDNA(hPGT)

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2801%2900183-1

7 January 2021

Possible role of anion exchanger AE2 as the intestinal monocarboxylic acid/anion antiporter

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2801%2900183-1

7 January 2021

Atypical multidrug resistance: breast cancer resistance protein messenger RNA expression in mitoxantrone-selected cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2801%2900183-1

7 January 2021

Role of metabolic enzymes and efflux transporters in the absorption of drugs from the small intestine

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2801%2900183-1

7 January 2021

Atorvastatin transport in the Caco-2 cell model: contributions of P-glycoprotein and the proton-monocarboxylic acid co-transporter

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2801%2900183-1

7 January 2021

Bisubstrates: substances that interact with both, renal contraluminal organic anion and organic cation transport systems. II. Zwitterionic substrates: dipeptides, cephalosporins, quinolone-carboxylate gyrase inhibitors and phosphamide thiazine carbo

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2801%2900183-1

7 January 2021

Predicting fraction dose absorbed in humans using a macroscopic mass balance approach

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2801%2900183-1

7 January 2021

Unexpected effect of verapamil on oral bioavailability of the beta-blocker talinolol in humans

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2801%2900183-1

7 January 2021

Regional intestinal permeability in rats of compounds with different physicochemical properties and transport mechanisms

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https://api.crossref.org/works/10.1016%2FS0169-409X%2801%2900183-1

7 January 2021

Segmental differences in drug permeability, esterase activity and ketone reductase activity in the albino rabbit intestine.

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https://api.crossref.org/works/10.1016%2FS0169-409X%2801%2900183-1

7 January 2021

Membrane transport of drugs in different regions of the intestinal tract of the rat.

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https://api.crossref.org/works/10.1016%2FS0169-409X%2801%2900183-1

7 January 2021

Non-ionic detergent Tween 80 modulates VP-16 resistance in classical multidrug resistant K562 cells via enhancement of VP-16 influx.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2801%2900183-1

7 January 2021

Fundamental relationships between the composition of pluronic block copolymers and their hypersensitization effect in MDR cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2801%2900183-1

7 January 2021

Pluronic P85 increases permeability of a broad spectrum of drugs in polarized BBMEC and Caco-2 cell monolayers

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https://api.crossref.org/works/10.1016%2FS0169-409X%2801%2900183-1

7 January 2021

Cremophor EL reversed multidrug resistance in vitro but not in tumor-bearing mouse models

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https://api.crossref.org/works/10.1016%2FS0169-409X%2801%2900183-1

7 January 2021

The use of surfactants to enhance the permeability of peptides through Caco-2 cells by inhibition of an apically polarized efflux system

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2801%2900183-1

7 January 2021

Mechanistic roles of neutral surfactants on concurrent polarized and passive membrane transport of a model peptide in Caco-2 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2801%2900183-1

7 January 2021

The effect of water-soluble vitamin E on cyclosporine pharmacokinetics in healthy volunteers

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2801%2900183-1

7 January 2021

Caco-2 versus Caco-2/HT29-MTX co-cultured cell lines: permeabilities via diffusion, inside- and outside-directed carrier-mediated transport

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2801%2900183-1

7 January 2021

Structure-permeation relations of met-enkephalin peptide analogues on absorption and secretion mechanisms in Caco-2 monolayers

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2801%2900183-1

7 January 2021

Pretreatment with potent P-glycoprotein ligands may increase intestinal secretion in rats

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https://api.crossref.org/works/10.1016%2FS0169-409X%2801%2900183-1

7 January 2021

Grapefruit juice enhances intestinal absorption of the P-glycoprotein substrate talinolol

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2801%2900183-1

7 January 2021

The effects of lipids and detergents on ATPase-active P-glycoprotein

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2801%2900183-1

7 January 2021

Reversal of multidrug resistance phenotype by surfactants: relationship to membrane lipid fluidity

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2801%2900183-1

7 January 2021

Effect of clarithromycin on renal excretion of digoxin: interaction with P-glycoprotein

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2801%2900183-1

7 January 2021

The contribution of P-glycoprotein to pharmacokinetic drug-drug interactions

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2801%2900183-1

7 January 2021

The role of intestinal P-glycoprotein in the interaction of digoxin and rifampin

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2801%2900183-1

7 January 2021

Induction of P-glycoprotein by rifampin increases intestinal secretion of talinolol in human beings: a new type of drug/drug interaction

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2801%2900183-1

7 January 2021

Pharmacokinetic interaction of digoxin with an herbal extract from St John's wort (Hypericum perforatum)

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2801%2900183-1

7 January 2021

Quercetin potentiates the effect of adriamycin in a multidrug-resistant MCF-7 human breast-cancer cell line: P-glycoprotein as a possible target

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2801%2900183-1

7 January 2021

Effect of quercetin on Hoechst 33342 transport by purified and reconstituted P-glycoprotein.

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https://api.crossref.org/works/10.1016%2FS0169-409X%2801%2900183-1

7 January 2021

Acceleration of MRP-associated efflux of rhodamine 123 by genistein and related compounds

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https://api.crossref.org/works/10.1016%2FS0169-409X%2801%2900183-1

7 January 2021

Grapefruit juice activates P-glycoprotein-mediated drug transport

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https://api.crossref.org/works/10.1016%2FS0169-409X%2801%2900183-1

7 January 2021

Modulation of adriamycin accumulation and efflux by flavonoids in HCT-15 colon cells. Activation of P-glycoprotein as a putative mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2801%2900183-1

7 January 2021

P-glycoprotein possesses a 1,4-dihydropyridine-selective drug acceptor site which is alloserically coupled to a vinca-alkaloid-selective binding site

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2801%2900183-1

7 January 2021

Inhibition of vinblastine efflux mediated by P-glycoprotein by grapefruit juice components in caco-2 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2801%2900183-1

7 January 2021

Inactivation of cytochrome P450 3A4 by bergamottin, a component of grapefruit juice

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https://api.crossref.org/works/10.1016%2FS0169-409X%2801%2900183-1

7 January 2021

Grapefruit juice greatly increases serum concentrations of lovastatin and lovastatin acid

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https://api.crossref.org/works/10.1016%2FS0169-409X%2801%2900183-1

7 January 2021

Drug-grapefruit juice interactions

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https://api.crossref.org/works/10.1016%2FS0169-409X%2801%2900183-1

7 January 2021

Inhibition of P-glycoprotein by orange juice components, polymethoxyflavones in adriamycin-resistant human myelogenous leukemia (K562/ADM) cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2801%2900183-1

7 January 2021

10.1016/S0169-409X(01)00183-1

Identifiers

DOI

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1 August 2017

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