Global assessment of promoter methylation in a mouse model of cancer identifies ID4 as a putative tumor-suppressor gene in human leukemia (Q34396332)

1 August 2017

Global assessment of promoter methylation in a mouse model of cancer identifies ID4 as a putative tumor-suppressor gene in human leukemia (English)

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Guido Marcucci

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John Byrd

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Michael A Caligiuri

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Laura Rassenti

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Aparna Raval

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Christoph Plass

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Shujun Liu

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Brian Becknell

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Zunyan Dai

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Charlene Mao

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Li Yu

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Chunhui Liu

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Jeff Vandeusen

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Yue-Zhong Wu

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Te-Hui Liu

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Wei Ding

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Laura T Smith

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Stephen Lee

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1 August 2017

language of work or name

English

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publication date

20 February 2005

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37

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265-274

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https://scigraph.springernature.com/pub.10.1038/ng1521

1 August 2017

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cites work

Focus on acute leukemias

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Worms gang up on bacteria

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Aberrant CpG-island methylation has non-random and tumour-type-specific patterns.

21 January 2018

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Global methylation profiling of lung cancer identifies novel methylated genes

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An AscI boundary library for the studies of genetic and epigenetic alterations in CpG islands

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A new tool for the rapid cloning of amplified and hypermethylated human DNA sequences from restriction landmark genome scanning gels

21 January 2018

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A NotI-EcoRV promoter library for studies of genetic and epigenetic alterations in mouse models of human malignancies

21 January 2018

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Downregulation of ID4 by promoter hypermethylation in gastric adenocarcinoma.

21 January 2018

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Epigenetic profiling in chronic lymphocytic leukemia reveals novel methylation targets

21 January 2018

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Id4 expression induces apoptosis in astrocytic cultures and is down-regulated by activation of the cAMP-dependent signal transduction pathway

21 January 2018

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Fatal leukemia in interleukin 15 transgenic mice follows early expansions in natural killer and memory phenotype CD8+ T cells.

21 January 2018

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Restriction landmark genome scanning.

21 January 2018

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Frequent epigenetic inactivation of the SLIT2 gene in gliomas

21 January 2018

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Induction of tumor angiogenesis by Slit-Robo signaling and inhibition of cancer growth by blocking Robo activity

21 January 2018

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Requirement for the orphan steroid receptor Nur77 in apoptosis of T-cell hybridomas

21 January 2018

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Apoptotic signals delivered through the T-cell receptor of a T-cell hybrid require the immediate-early gene nur77.

21 January 2018

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Integration of calcineurin and MEF2 signals by the coactivator p300 during T-cell apoptosis

21 January 2018

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GPC6, a novel member of the glypican gene family, encodes a product structurally related to GPC4 and is colocalized with GPC5 on human chromosome 13

21 January 2018

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Glypicans in growth control and cancer

21 January 2018

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Overexpression of Id protein inhibits the muscle differentiation program: in vivo association of Id with E2A proteins

21 January 2018

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Inhibition of myeloid differentiation by the helix-loop-helix protein Id

21 January 2018

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The helix-loop-helix protein Id-2 enhances cell proliferation and binds to the retinoblastoma protein

21 January 2018

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Id2 specifically alters regulation of the cell cycle by tumor suppressor proteins

21 January 2018

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Id proteins at the cross-road of development and cancer

21 January 2018

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Each member of the Id gene family exhibits a unique expression pattern in mouse gastrulation and neurogenesis.

21 January 2018

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Id4 expression and its relationship to other Id genes during avian embryonic development

21 January 2018

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BRCA1 transcriptionally regulates genes involved in breast tumorigenesis

21 January 2018

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Identification of Id4 as a regulator of BRCA1 expression by using a ribozyme-library-based inverse genomics approach

21 January 2018

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Increased expression of unmethylated CDKN2D by 5-aza-2'-deoxycytidine in human lung cancer cells

21 January 2018

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Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands

21 January 2018

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The fundamental role of epigenetic events in cancer

21 January 2018

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7 January 2021

Novel methylation targets in de novo acute myeloid leukemia with prevalence of chromosome 11 loci

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7 January 2021

An intermolecular disulfide bond stabilizes E2A homodimers and is required for DNA binding at physiological temperatures

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7 January 2021

Degradation of Id proteins by the ubiquitin-proteasome pathway

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7 January 2021

Computational identification of promoters and first exons in the human genome

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7 January 2021

Identifiers

DOI

10.1038/NG1521

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1 August 2017

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