Phenotypic and genotypic characterization of influenza virus mutants selected with the sialidase fusion protein DAS181 (Q34405859)

2 August 2017

title

Phenotypic and genotypic characterization of influenza virus mutants selected with the sialidase fusion protein DAS181 (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21097900

1 September 2024

main subject

viral drug resistance

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21097900

1 September 2024

genetic selection

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21097900

1 September 2024

author name string

Maria Hedlund

3

1 reference

2 August 2017

Fang Fang

7

1 reference

2 August 2017

Gallen B. Triana-Baltzer

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21097900

1 September 2024

Rebecca L. Sanders

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21097900

1 September 2024

Kellie A. Jensen

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21097900

1 September 2024

Laura M. Aschenbrenner

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21097900

1 September 2024

Jeffrey L. Larson

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21097900

1 September 2024

language of work or name

English

0 references

publication date

21 November 2010

1 reference

full work available at URL

2 August 2017

number of pages

14

1 reference

based on heuristic

inferred from page(s)

https://academic.oup.com/jac/article-pdf/66/1/15/13760175/dkq387.pdf

file format

Portable Document Format

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21097900

http://jac.oxfordjournals.org/cgi/content/abstract/66/1/15

1 September 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21097900

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21097900/?tool=EBI

1 September 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21097900

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21097900/pdf/?tool=EBI

1 September 2024

file format

Portable Document Format

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21097900

https://europepmc.org/articles/PMC3001847

1 September 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21097900

https://europepmc.org/articles/PMC3001847?pdf=render

1 September 2024

file format

Portable Document Format

content deliverer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21097900

https://doi.org/10.1093/jac/dkq387

1 September 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21097900

Journal of Antimicrobial Chemotherapy

1 September 2024

published in

1 reference

2 August 2017

volume

66

1 reference

2 August 2017

issue

1

1 reference

2 August 2017

page(s)

15-28

1 reference

Oseltamivir resistance and the H274Y neuraminidase mutation in seasonal, pandemic and highly pathogenic influenza viruses.

2 August 2017

cites work

1 reference

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DAS181, a sialidase fusion protein, protects human airway epithelium against influenza virus infection: an in vitro pharmacodynamic analysis

6 July 2018

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Inhibition of neuraminidase inhibitor-resistant influenza virus by DAS181, a novel sialidase fusion protein

6 July 2018

1 reference

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Novel pandemic influenza A(H1N1) viruses are potently inhibited by DAS181, a sialidase fusion protein.

6 July 2018

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6 July 2018

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DAS181 inhibits H5N1 influenza virus infection of human lung tissues

6 July 2018

1 reference

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6 July 2018

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6 July 2018

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Recent avian H5N1 viruses exhibit increased propensity for acquiring human receptor specificity.

6 July 2018

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6 July 2018

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Contemporary North American influenza H7 viruses possess human receptor specificity: Implications for virus transmissibility.

6 July 2018

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DAS181, a novel sialidase fusion protein, protects mice from lethal avian influenza H5N1 virus infection.

6 July 2018

1 reference

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Structural basis for receptor specificity of influenza B virus hemagglutinin

6 July 2018

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Characterization of human H1N1 influenza virus variants selected in vitro with zanamivir in the presence of sialic acid-containing molecules

6 July 2018

1 reference

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Receptor binding specificity of recent human H3N2 influenza viruses

6 July 2018

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Emergence of influenza B viruses with reduced sensitivity to neuraminidase inhibitors

6 July 2018

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Characterization of drug-resistant recombinant influenza A/H1N1 viruses selected in vitro with peramivir and zanamivir

6 July 2018

1 reference

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Haemagglutinin mutations responsible for the binding of H5N1 influenza A viruses to human-type receptors

6 July 2018

1 reference

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Sialidase fusion protein as a novel broad-spectrum inhibitor of influenza virus infection.

6 July 2018

1 reference

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Structure and receptor specificity of the hemagglutinin from an H5N1 influenza virus

6 July 2018

1 reference

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Oseltamivir resistance--disabling our influenza defenses

6 July 2018

1 reference

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Glycan microarray analysis of the hemagglutinins from modern and pandemic influenza viruses reveals different receptor specificities.

6 July 2018

1 reference

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Enhanced expression of an alpha2,6-linked sialic acid on MDCK cells improves isolation of human influenza viruses and evaluation of their sensitivity to a neuraminidase inhibitor

6 July 2018

1 reference

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Emergence of amantadine-resistant influenza A viruses: epidemiological study

6 July 2018

1 reference

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Overexpression of the alpha-2,6-sialyltransferase in MDCK cells increases influenza virus sensitivity to neuraminidase inhibitors

6 July 2018

1 reference

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Neuraminidase sequence analysis and susceptibilities of influenza virus clinical isolates to zanamivir and oseltamivir.

6 July 2018

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X-ray structure of the hemagglutinin of a potential H3 avian progenitor of the 1968 Hong Kong pandemic influenza virus

6 July 2018

1 reference

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Mechanism by which mutations at his274 alter sensitivity of influenza a virus n1 neuraminidase to oseltamivir carboxylate and zanamivir

6 July 2018

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A release-competent influenza A virus mutant lacking the coding capacity for the neuraminidase active site

6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

1 reference

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6 July 2018

1 reference

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The interaction of neuraminidase and hemagglutinin mutations in influenza virus in resistance to 4-guanidino-Neu5Ac2en

6 July 2018

1 reference

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Generation and characterization of a mutant of influenza A virus selected with the neuraminidase inhibitor BCX-140.

6 July 2018

1 reference

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Mutations in a conserved residue in the influenza virus neuraminidase active site decreases sensitivity to Neu5Ac2en-derived inhibitors

6 July 2018

1 reference

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6 July 2018

1 reference

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Catalytic and framework mutations in the neuraminidase active site of influenza viruses that are resistant to 4-guanidino-Neu5Ac2en.

6 July 2018

1 reference

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Generation and characterization of variants of NWS/G70C influenza virus after in vitro passage in 4-amino-Neu5Ac2en and 4-guanidino-Neu5Ac2en.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001847

Characterization of mutants of influenza A virus selected with the neuraminidase inhibitor 4-guanidino-Neu5Ac2en

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001847

Generation and characterization of an influenza virus neuraminidase variant with decreased sensitivity to the neuraminidase-specific inhibitor 4-guanidino-Neu5Ac2en

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001847

Sequence and structure alignment of paramyxovirus hemagglutinin-neuraminidase with influenza virus neuraminidase.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001847

Three-dimensional structure of the complex of 4-guanidino-Neu5Ac2en and influenza virus neuraminidase

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001847

Plaque inhibition assay for drug susceptibility testing of influenza viruses

6 July 2018

1 reference

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The neuraminidase of influenza virus

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001847

Emergence and transmission of influenza A viruses resistant to amantadine and rimantadine

6 July 2018

1 reference

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Swine flu outbreak. What role for antiviral drugs?

6 July 2018

1 reference

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Update: drug susceptibility of swine-origin influenza A (H1N1) viruses, April 2009.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001847

Infections with oseltamivir-resistant influenza A(H1N1) virus in the United States

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001847

Glycan topology determines human adaptation of avian H5N1 virus hemagglutinin

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001847

In vitro generation and characterisation of an influenza B variant with reduced sensitivity to neuraminidase inhibitors

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001847

A point mutation in influenza B neuraminidase confers resistance to peramivir and loss of slow binding

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001847

Selection and characterization of a neuraminidase-minus mutant of influenza virus and its rescue by cloned neuraminidase genes.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001847

Universal primer set for the full-length amplification of all influenza A viruses

27 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21097900

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1093/JAC/DKQ387

1 reference

2 August 2017

1 reference

2 August 2017

1 reference