Viral oncoproteins E1A and E7 and cellular LxCxE proteins repress SUMO modification of the retinoblastoma tumor suppressor (Q34408391)

2 August 2017

title

Viral oncoproteins E1A and E7 and cellular LxCxE proteins repress SUMO modification of the retinoblastoma tumor suppressor (English)

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2 August 2017

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Stefan Müller

3

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author name string

Andreas Ledl

series ordinal

1

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2 August 2017

Darja Schmidt

series ordinal

2

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2 August 2017

language of work or name

English

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publication date

1 May 2005

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2 August 2017

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2 August 2017

volume

24

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2 August 2017

issue

23

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2 August 2017

page(s)

3810-3818

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Retinoblastoma protein recruits histone deacetylase to repress transcription

2 August 2017

cites work

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The B-domain lysine patch of pRB is required for binding to large T antigen and release of E2F by phosphorylation

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Role of LXCXE motif-dependent interactions in the activity of the retinoblastoma protein

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Retinoblastoma protein positively regulates terminal adipocyte differentiation through direct interaction with C/EBPs

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Retinoblastoma protein directly interacts with and activates the transcription factor NF-IL6

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The retinoblastoma tumour suppressor in development and cancer

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Role of the LXCXE binding site in Rb function

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SUMO-1 modification of histone deacetylase 1 (HDAC1) modulates its biological activities

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Three regions of the pRB pocket domain affect its inactivation by human papillomavirus E7 proteins

21 January 2018

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Mutagenesis of the pRB pocket reveals that cell cycle arrest functions are separable from binding to viral oncoproteins

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The Rb/E2F pathway: expanding roles and emerging paradigms

21 January 2018

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Cdk phosphorylation triggers sequential intramolecular interactions that progressively block Rb functions as cells move through G1

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An E3-like factor that promotes SUMO conjugation to the yeast septins

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Protein modification by SUMO

21 January 2018

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The polycomb protein Pc2 is a SUMO E3

21 January 2018

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Structural basis for the inactivation of retinoblastoma tumor suppressor by SV40 large T antigen

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The SUMO E3 ligase RanBP2 promotes modification of the HDAC4 deacetylase

21 January 2018

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Differential regulation of retinoblastoma protein function by specific Cdk phosphorylation sites

21 January 2018

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Structural basis for the recognition of the E2F transactivation domain by the retinoblastoma tumor suppressor

21 January 2018

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Structure of the retinoblastoma tumour-suppressor pocket domain bound to a peptide from HPV E7

21 January 2018

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New roles for the RB tumor suppressor protein

21 January 2018

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Rb interacts with histone deacetylase to repress transcription

21 January 2018

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A novel Rb- and p300-binding protein inhibits transactivation by MyoD

21 January 2018

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Retinoblastoma protein represses transcription by recruiting a histone deacetylase

21 January 2018

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SUMO--nonclassical ubiquitin

21 January 2018

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Cells degrade a novel inhibitor of differentiation with E1A-like properties upon exiting the cell cycle

21 January 2018

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Retinoblastoma protein partners

21 January 2018

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SUMO, ubiquitin's mysterious cousin

21 January 2018

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SUMO: a regulator of gene expression and genome integrity.

21 January 2018

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Acetylation regulates the differentiation-specific functions of the retinoblastoma protein

21 January 2018

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Rb targets histone H3 methylation and HP1 to promoters

21 January 2018

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pRb is required for MEF2-dependent gene expression as well as cell-cycle arrest during skeletal muscle differentiation

21 January 2018

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The nucleoporin RanBP2 has SUMO1 E3 ligase activity

21 January 2018

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Members of the PIAS family act as SUMO ligases for c-Jun and p53 and repress p53 activity

21 January 2018

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PIAS/SUMO: new partners in transcriptional regulation.

21 January 2018

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Nuclear and unclear functions of SUMO

21 January 2018

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Principles of tumor suppression

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The RB and p53 pathways in cancer

21 January 2018

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Cdk-mediated phosphorylation of pRB regulates HDAC binding in vitro

21 January 2018

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The retinoblastoma protein acts as a transcriptional coactivator required for osteogenic differentiation

21 January 2018

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Modification with SUMO. A role in transcriptional regulation

21 January 2018

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Identification and characterization of a novel human cDNA encoding a 21 kDa pRb-associated protein

21 January 2018

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Crystal structure of the retinoblastoma tumor suppressor protein bound to E2F and the molecular basis of its regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208539

SUMO promotes HDAC-mediated transcriptional repression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208539

c-Jun and p53 Activity Is Modulated by SUMO-1 Modification

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208539

Acetylation control of the retinoblastoma tumour-suppressor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208539

7 January 2021

p300 Transcriptional Repression Is Mediated by SUMO Modification

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208539

7 January 2021

Cyclin E-induced S phase without activation of the pRb/E2F pathway.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208539

7 January 2021

Differential phosphorylation of the retinoblastoma protein by G1/S cyclin-dependent kinases

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7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1208539

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Dimensions Publication ID

2 August 2017

1025606018

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