Quinacrine treatment trial for sporadic Creutzfeldt-Jakob disease (Q34415659)

2 August 2017

Quinacrine treatment trial for sporadic Creutzfeldt-Jakob disease (English)

1 reference

2 August 2017

18

Stanley B Prusiner

1 reference

2 August 2017

19

Bruce L Miller

1 reference

2 August 2017

1

Michael D Geschwind

1 reference

2 August 2017

Amy L Kuo

2

1 reference

2 August 2017

Katherine S Wong

3

1 reference

2 August 2017

Aissa Haman

4

1 reference

2 August 2017

Gillian Devereux

5

1 reference

2 August 2017

Benjamin J Raudabaugh

6

1 reference

2 August 2017

David Y Johnson

7

1 reference

2 August 2017

Charles C Torres-Chae

8

1 reference

2 August 2017

Ron Finley

9

1 reference

2 August 2017

Paul Garcia

10

1 reference

2 August 2017

Julie N Thai

11

1 reference

2 August 2017

Hugo Q Cheng

12

1 reference

2 August 2017

John M Neuhaus

13

1 reference

2 August 2017

Sven A Forner

14

1 reference

2 August 2017

Jacque L Duncan

15

1 reference

2 August 2017

Katherine L Possin

16

1 reference

2 August 2017

Stephen J Dearmond

17

1 reference

2 August 2017

language of work or name

English

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publication date

11 October 2013

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2 August 2017

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2 August 2017

81

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2 August 2017

23

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2 August 2017

2015-2023

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Conformational transformation and selection of synthetic prion strains

2 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4211922

Efficacy of novel acridine derivatives in the inhibition of hPrP90-231 prion protein fragment toxicity

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4211922

Darwinian evolution of prions in cell culture

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4211922

Continuous quinacrine treatment results in the formation of drug-resistant prions

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4211922

Safety and efficacy of quinacrine in human prion disease (PRION-1 study): a patient-preference trial

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4211922

Clinical trials for prion disease: difficult challenges, but hope for the future

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4211922

Emerging pharmacotherapies for Creutzfeldt-Jakob disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4211922

Quinacrine is mainly metabolized to mono-desethyl quinacrine by CYP3A4/5 and its brain accumulation is limited by P-glycoprotein

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4211922

A possible pharmacological explanation for quinacrine failure to treat prion diseases: pharmacokinetic investigations in a ovine model of scrapie

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4211922

Compassionate use of quinacrine in Creutzfeldt-Jakob disease fails to show significant effects

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4211922

Pharmacokinetics of quinacrine in the treatment of prion disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4211922

Antimalarial drug quinacrine binds to C-terminal helix of cellular prion protein

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4211922

Evaluation of quinacrine treatment for prion diseases

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4211922

Potent inhibition of scrapie prion replication in cultured cells by bis-acridines

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4211922

Acridine and phenothiazine derivatives as pharmacotherapeutics for prion disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4211922

The CONSORT statement: revised recommendations for improving the quality of reports of parallel-group randomised trials

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4211922

The revised CONSORT statement for reporting randomized trials: explanation and elaboration

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4211922

Lysosomotropic agents and cysteine protease inhibitors inhibit scrapie-associated prion protein accumulation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4211922

The Clinical Dementia Rating (CDR): current version and scoring rules

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4211922

Antimalarial agents and lupus.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4211922

The Neuropsychiatric Inventory: comprehensive assessment of psychopathology in dementia

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4211922

Interobserver agreement for the assessment of handicap in stroke patients.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4211922

Improving the sensitivity of the Barthel Index for stroke rehabilitation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4211922

A Multiple Testing Procedure for Clinical Trials

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4211922

Toxicity of quinacrine can be reduced by co-administration of P-glycoprotein inhibitor in sporadic Creutzfeldt-Jakob disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4211922

Efficacy of flupirtine on cognitive function in patients with CJD: A double-blind study

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4211922

Results of quinacrine administration to patients with Creutzfeldt-Jakob disease.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4211922

Differential inhibition of prion propagation by enantiomers of quinacrine

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4211922

Quinacrine effects on the central nervous system.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4211922

Quinacrine does not prolong survival in a murine Creutzfeldt-Jakob disease model

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4211922

Antimalarial psychosis revisited

27 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24122181

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1212/WNL.0B013E3182A9F3B4

1 reference

2 August 2017

1 reference

2 August 2017

1 reference