The TSC1-TSC2 complex consists of multiple TSC1 and TSC2 subunits (Q34420296)

2 August 2017

title

The TSC1-TSC2 complex consists of multiple TSC1 and TSC2 subunits (English)

1 reference

2 August 2017

author name string

Marianne Hoogeveen-Westerveld

1

1 reference

2 August 2017

Leontine van Unen

2

1 reference

2 August 2017

Ans van den Ouweland

3

1 reference

2 August 2017

Dicky Halley

4

1 reference

2 August 2017

Andre Hoogeveen

5

1 reference

2 August 2017

Mark Nellist

6

1 reference

2 August 2017

language of work or name

1 reference

24 September 2012

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2 August 2017

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2 August 2017

volume

13

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2 August 2017

page(s)

18

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Caught in self-interaction: evolutionary and functional mechanisms of protein homooligomerization

2 August 2017

cites work

1 reference

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6 July 2018

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Tuberous sclerosis tumor suppressor complex-like complexes act as GTPase-activating proteins for Ral GTPases

6 July 2018

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A reliable cell-based assay for testing unclassified TSC2 gene variants

6 July 2018

1 reference

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The TSC1-TSC2 complex: a molecular switchboard controlling cell growth

6 July 2018

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Defining the role of mTOR in cancer

6 July 2018

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N-terminal hamartin-binding and C-terminal GAP domain of tuberin can separate in vivo

6 July 2018

1 reference

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Activation of mammalian target of rapamycin (mTOR) by insulin is associated with stimulation of 4EBP1 binding to dimeric mTOR complex 1

6 July 2018

1 reference

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Activity of TSC2 is inhibited by AKT-mediated phosphorylation and membrane partitioning

6 July 2018

1 reference

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Localization of Rheb to the endomembrane is critical for its signaling function

6 July 2018

1 reference

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Adipocytes contain a novel complex similar to the tuberous sclerosis complex

6 July 2018

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Molecular organization of target of rapamycin complex 2.

6 July 2018

1 reference

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TSC2: filling the GAP in the mTOR signaling pathway

6 July 2018

1 reference

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Metastasis of benign tumor cells in tuberous sclerosis complex

6 July 2018

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Loss of Tsc1/Tsc2 activates mTOR and disrupts PI3K-Akt signaling through downregulation of PDGFR

6 July 2018

1 reference

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Regulation of TSC2 by 14-3-3 binding

6 July 2018

1 reference

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Identification and characterization of the interaction between tuberin and 14-3-3zeta

6 July 2018

1 reference

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Phosphatidylinositol 3-kinase/Akt pathway regulates tuberous sclerosis tumor suppressor complex by phosphorylation of tuberin

6 July 2018

1 reference

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TSC2 missense mutations inhibit tuberin phosphorylation and prevent formation of the tuberin-hamartin complex

6 July 2018

1 reference

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The tuberous sclerosis-1 (TSC1) gene product hamartin suppresses cell growth and augments the expression of the TSC2 product tuberin by inhibiting its ubiquitination

6 July 2018

1 reference

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Characterization of the cytosolic tuberin-hamartin complex. Tuberin is a cytosolic chaperone for hamartin

6 July 2018

1 reference

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Oligomerization properties of fragile-X mental-retardation protein (FMRP) and the fragile-X-related proteins FXR1P and FXR2P

6 July 2018

1 reference

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Interaction between hamartin and tuberin, the TSC1 and TSC2 gene products

6 July 2018

1 reference

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Identification of the tuberous sclerosis gene TSC1 on chromosome 9q34

6 July 2018

1 reference

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The FMR-1 protein is cytoplasmic, most abundant in neurons and appears normal in carriers of a fragile X premutation

6 July 2018

1 reference

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Identification and characterization of the tuberous sclerosis gene on chromosome 16

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3517901

Analysis of TSC1 truncations defines regions involved in TSC1 stability, aggregation and interaction

6 July 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2091-13-18

Rheb fills a GAP between TSC and TOR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2091-13-18

Distinct effects of single amino-acid changes to tuberin on the function of the tuberin-hamartin complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2091-13-18

Nutrient-dependent multimerization of the mammalian target of rapamycin through the N-terminal HEAT repeat region.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2091-13-18

Functional assessment of variants in the TSC1 and TSC2 genes identified in individuals with Tuberous Sclerosis Complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2091-13-18

The proteins encoded by c-akt and v-akt differ in post-translational modification, subcellular localization and oncogenic potential.

21 January 2018

1 reference

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Unusually mild tuberous sclerosis phenotype is associated withTSC2R905Q mutation

27 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23006675

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1186/1471-2091-13-18

1 reference

2 August 2017

1 reference

2 August 2017

1 reference