Olaparib maintenance therapy in patients with platinum-sensitive relapsed serous ovarian cancer: a preplanned retrospective analysis of outcomes by BRCA status in a randomised phase 2 trial. (Q34422265)

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English	Olaparib maintenance therapy in patients with platinum-sensitive relapsed serous ovarian cancer: a preplanned retrospective analysis of outcomes by BRCA status in a randomised phase 2 trial.	scientific article

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19 March 2020

Olaparib maintenance therapy in patients with platinum-sensitive relapsed serous ovarian cancer: a preplanned retrospective analysis of outcomes by BRCA status in a randomised phase 2 trial (English)

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19 March 2020

phase II clinical trial

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Daniela E. Matei

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19 March 2020

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Ignace Vergote

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19 March 2020

Ronnie Shapira-Frommer

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Ronnie Shapira-Frommer

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19 March 2020

Ursula A. Matulonis

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Ursula Matulonis

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19 March 2020

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Jonathan Ledermann

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19 March 2020

Philipp Harter

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19 March 2020

Charlie Gourley

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19 March 2020

Michael Friedlander

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19 March 2020

Gordon Rustin

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19 March 2020

Clare L Scott

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19 March 2020

Werner Meier

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19 March 2020

Tamar Safra

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19 March 2020

Anitra Fielding

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19 March 2020

Stuart Spencer

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19 March 2020

Brian Dougherty

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19 March 2020

Maria Orr

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19 March 2020

Darren Hodgson

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19 March 2020

J Carl Barrett

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19 March 2020

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31 May 2014

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19 March 2020

Lancet Oncology Commission

1 reference

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19 March 2020

15

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19 March 2020

8

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19 March 2020

852-861

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24882434%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

Cancer incidence and mortality patterns in Europe: estimates for 40 countries in 2012

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Newly diagnosed and relapsed epithelial ovarian carcinoma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2814%2970228-1

7 January 2021

based on heuristic

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Ovarian carcinomas with genetic and epigenetic BRCA1 loss have distinct molecular abnormalities

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2814%2970228-1

7 January 2021

based on heuristic

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Integrated genomic analyses of ovarian carcinoma

1 reference

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7 January 2021

based on heuristic

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BRCA mutation frequency and patterns of treatment response in BRCA mutation-positive women with ovarian cancer: a report from the Australian Ovarian Cancer Study Group

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2814%2970228-1

7 January 2021

based on heuristic

inferred from DOI database lookup

BRCA1 and BRCA2 mutations account for a large proportion of ovarian carcinoma cases

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2814%2970228-1

7 January 2021

based on heuristic

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Population BRCA1 and BRCA2 mutation frequencies and cancer penetrances: a kin-cohort study in Ontario, Canada

1 reference

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BRCA1/2 mutations and expression: Response to platinum chemotherapy in patients with advanced stage epithelial ovarian cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2814%2970228-1

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Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy

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A synthetic lethal therapeutic approach: poly(ADP) ribose polymerase inhibitors for the treatment of cancers deficient in DNA double-strand break repair

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Oral poly(ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and recurrent ovarian cancer: a proof-of-concept trial

1 reference

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7 January 2021

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Inhibition of poly(ADP-ribose) polymerase in tumors from BRCA mutation carriers

1 reference

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Poly(ADP)-ribose polymerase inhibition: frequent durable responses in BRCA carrier ovarian cancer correlating with platinum-free interval

1 reference

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Olaparib in patients with recurrent high-grade serous or poorly differentiated ovarian carcinoma or triple-negative breast cancer: a phase 2, multicentre, open-label, non-randomised study

1 reference

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Phase II, open-label, randomized, multicenter study comparing the efficacy and safety of olaparib, a poly (ADP-ribose) polymerase inhibitor, and pegylated liposomal doxorubicin in patients with BRCA1 or BRCA2 mutations and recurrent ovarian cancer

1 reference

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Olaparib Maintenance Therapy in Platinum-Sensitive Relapsed Ovarian Cancer

1 reference

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7 January 2021

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1 reference

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7 January 2021

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1 reference

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1 reference

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10.1016/S1470-2045(14)70228-1

1 reference

Europe PubMed Central

PubMed publication ID

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19 March 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24882434%20AND%20SRC:MED&resulttype=core&format=json

19 March 2020

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