Pigment epithelial-derived factor (PEDF)-triggered lung cancer cell apoptosis relies on p53 protein-driven Fas ligand (Fas-L) up-regulation and Fas protein cell surface translocation. (Q34431110)

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English	Pigment epithelial-derived factor (PEDF)-triggered lung cancer cell apoptosis relies on p53 protein-driven Fas ligand (Fas-L) up-regulation and Fas protein cell surface translocation.	scientific article

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16 February 2020

Pigment epithelial-derived factor (PEDF)-triggered lung cancer cell apoptosis relies on p53 protein-driven Fas ligand (Fas-L) up-regulation and Fas protein cell surface translocation (English)

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Lei Li

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16 February 2020

Ya-Chao Yao

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16 February 2020

Shu-Huan Fang

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16 February 2020

Cai-Qi Ma

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Yi Cen

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16 February 2020

Zu-Min Xu

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Cen Li

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Shuai Li

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16 February 2020

Ting Zhang

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16 February 2020

Hong-Hai Hong

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16 February 2020

Wei-Wei Qi

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16 February 2020

Ti Zhou

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16 February 2020

Chao-Yang Li

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16 February 2020

Xia Yang

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16 February 2020

Guo-Quan Gao

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16 February 2020

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15 September 2014

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16 February 2020

Journal of Biological Chemistry

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16 February 2020

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16 February 2020

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16 February 2020

30785-30799

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16 February 2020

Pigment epithelium-derived factor gene loaded in cRGD-PEG-PEI suppresses colorectal cancer growth by targeting endothelial cells.

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Molecular mechanism implicated in Pemetrexed-induced apoptosis in human melanoma cells

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AAV-mediated gene transfer of human pigment epithelium-derived factor inhibits Lewis lung carcinoma growth in mice

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Acrolein induces apoptosis through the death receptor pathway in A549 lung cells: role of p53.

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6 July 2018

In vitro and in vivo biological activity of PEDF against a range of tumors.

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6 July 2018

PEDF inhibits growth of retinoblastoma by anti-angiogenic activity

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6 July 2018

The role of FasL and Fas in health and disease.

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6 July 2018

The molecular impact of pigment epithelium-derived factor, PEDF, on lung cancer cells and the clinical significance

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6 July 2018

Peroxisome proliferator-activated receptor gamma activates fas ligand gene promoter inducing apoptosis in human breast cancer cells

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6 July 2018

PEDF induces p53-mediated apoptosis through PPAR gamma signaling in human umbilical vein endothelial cells

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Pigment epithelium-derived factor overexpression inhibits orthotopic osteosarcoma growth, angiogenesis and metastasis

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6 July 2018

Adenovirus-mediated PEDF expression inhibits prostate cancer cell growth and results in augmented expression of PAI-2.

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6 July 2018

p53 enhances gefitinib-induced growth inhibition and apoptosis by regulation of Fas in non-small cell lung cancer

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Pigment epithelium-derived factor: a multimodal tumor inhibitor

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6 July 2018

Ionizing radiation suppresses FAP-1 mRNA level in A549 cells via p53 activation

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6 July 2018

Pigment epithelium-derived factor (PEDF) is an endogenous antiinflammatory factor

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6 July 2018

Pigment epithelium-derived factor inhibits angiogenesis via regulated intracellular proteolysis of vascular endothelial growth factor receptor 1

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Does CD95 have tumor promoting activities?

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6 July 2018

Inhibition of glioma invasion by overexpression of pigment epithelium-derived factor

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Overexpression of pigment epithelium-derived factor decreases angiogenesis and inhibits the growth of human malignant melanoma cells in vivo

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6 July 2018

FAP-1 association with Fas (Apo-1) inhibits Fas expression on the cell surface

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Initiator caspases in apoptosis signaling pathways

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6 July 2018

Inducer-stimulated Fas targets activated endothelium for destruction by anti-angiogenic thrombospondin-1 and pigment epithelium-derived factor

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6 July 2018

Identification of two Fas-associated phosphatase-1 (FAP-1) promoters in human cancer cells

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FAP-1 in pancreatic cancer cells: functional and mechanistic studies on its inhibitory role in CD95-mediated apoptosis.

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Prevention of ischemia-induced retinopathy by the natural ocular antiangiogenic agent pigment epithelium-derived factor

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Defining CD95 as a tumor suppressor gene

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Fas preassociation required for apoptosis signaling and dominant inhibition by pathogenic mutations

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Bile salts mediate hepatocyte apoptosis by increasing cell surface trafficking of Fas.

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Human and mouse Fas (APO-1/CD95) death receptor genes each contain a p53-responsive element that is activated by p53 mutants unable to induce apoptosis

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Cytosolic phospholipase A2-{alpha} is an early apoptotic activator in PEDF-induced endothelial cell apoptosis

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Cell surface trafficking of Fas: a rapid mechanism of p53-mediated apoptosis.

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Analysis of Fas and Fas ligand expression and function in lung cancer cell lines

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CD95 (Fas) expression is regulated by sequestration in the Golgi complex in B-cell lymphoma

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12 December 2020

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Anti-Fas on nonhematopoietic tumors: levels of Fas/APO-1 and bcl-2 are not predictive of biological responsiveness

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MicroRNA-23b promotes tolerogenic properties of dendritic cells in vitro through inhibiting Notch1/NF-κB signalling pathways

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Identifiers

10.1074/JBC.M114.590000

1 reference

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16 February 2020

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16 February 2020

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Europe PubMed Central

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16 February 2020

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