Two novel human NUMB isoforms provide a potential link between development and cancer (Q34439241)

2 August 2017

Two novel human NUMB isoforms provide a potential link between development and cancer (English)

1 reference

2 August 2017

Aldona Karaczyn

1

1 reference

2 August 2017

Mahmud Bani-Yaghoub

2

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2 August 2017

Roger Tremblay

3

1 reference

2 August 2017

Chris Kubu

4

1 reference

2 August 2017

Rebecca Cowling

5

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2 August 2017

Tamara L Adams

6

1 reference

2 August 2017

Igor Prudovsky

7

1 reference

2 August 2017

Douglas Spicer

8

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2 August 2017

Robert Friesel

9

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2 August 2017

Calvin Vary

10

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2 August 2017

Joseph M Verdi

11

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2 August 2017

1 December 2010

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2 August 2017

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2 August 2017

5

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2 August 2017

31

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https://scigraph.springernature.com/pub.10.1186/1749-8104-5-31

2 August 2017

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cites work

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NUMB controls p53 tumour suppressor activity

6 July 2018

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Numb and Numbl are required for maintenance of cadherin-based adhesion and polarity of neural progenitors

6 July 2018

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Asymmetric stem cell division in development and cancer.

6 July 2018

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Novel natural immunogenic peptides from Numb1 and Notch1 proteins for CD8+ cells in ovarian ascites

6 July 2018

1 reference

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aPKC-mediated phosphorylation regulates asymmetric membrane localization of the cell fate determinant Numb

6 July 2018

1 reference

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NUMB is a break of WNT-Notch signaling cycle.

6 July 2018

1 reference

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Aberrant activation of notch signaling in human breast cancer

6 July 2018

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Role of numb in dendritic spine development with a Cdc42 GEF intersectin and EphB2.

6 July 2018

1 reference

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Target selectivity of vertebrate notch proteins. Collaboration between discrete domains and CSL-binding site architecture determines activation probability

6 July 2018

1 reference

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Key Regulators in Neuronal Polarity

6 July 2018

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Phosphorylation by Rho kinase regulates CRMP-2 activity in growth cones

6 July 2018

1 reference

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PAR-6-PAR-3 mediates Cdc42-induced Rac activation through the Rac GEFs STEF/Tiam1.

6 July 2018

1 reference

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A new cytoskeletal connection for APC: linked to actin through IQGAP

6 July 2018

1 reference

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Loss of negative regulation by Numb over Notch is relevant to human breast carcinogenesis

6 July 2018

1 reference

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CRMP-2 regulates polarized Numb-mediated endocytosis for axon growth

6 July 2018

1 reference

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IQGAP proteins are integral components of cytoskeletal regulation

6 July 2018

1 reference

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IQGAP1 as signal integrator: Ca2+, calmodulin, Cdc42 and the cytoskeleton

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009962

Mammalian numb proteins promote Notch1 receptor ubiquitination and degradation of the Notch1 intracellular domain

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009962

Involvement of numb in vertebrate retinal development: evidence for multiple roles of numb in neural differentiation and maturation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009962

Progenitor cell maintenance requires numb and numblike during mouse neurogenesis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009962

Asymmetric Numb distribution is critical for asymmetric cell division of mouse cerebral cortical stem cells and neuroblasts

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009962

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009962

Mouse numb is an essential gene involved in cortical neurogenesis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009962

Human NT2/D1 cells differentiate into functional astrocytes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009962

Activation of LIM-kinase by Pak1 couples Rac/Cdc42 GTPase signalling to actin cytoskeletal dynamics

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009962

Distinct human NUMB isoforms regulate differentiation vs. proliferation in the neuronal lineage

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009962

NUMB localizes in the basal cortex of mitotic avian neuroepithelial cells and modulates neuronal differentiation by binding to NOTCH-1.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009962

The effects of gap junction blockage on neuronal differentiation of human NTera2/clone D1 cells

6 July 2018

1 reference

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Reduction of connexin43 expression and dye-coupling during neuronal differentiation of human NTera2/clone D1 cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009962

Mammalian NUMB is an evolutionarily conserved signaling adapter protein that specifies cell fate

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009962

Asymmetric localization of a mammalian numb homolog during mouse cortical neurogenesis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009962

Numb antagonizes Notch signaling to specify sibling neuron cell fates

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009962

Asymmetric distribution of numb protein during division of the sensory organ precursor cell confers distinct fates to daughter cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009962

Expression of trk in MAH cells lacking the p75 low-affinity nerve growth factor receptor is sufficient to permit nerve growth factor-induced differentiation to postmitotic neurons

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009962

p75LNGFR regulates Trk signal transduction and NGF-induced neuronal differentiation in MAH cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009962

numb, a gene required in determination of cell fate during sensory organ formation in Drosophila embryos

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009962

Pure, postmitotic, polarized human neurons derived from NTera 2 cells provide a system for expressing exogenous proteins in terminally differentiated neurons

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009962

In-gel digestion of proteins for internal sequence analysis after one- or two-dimensional gel electrophoresis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009962

Numb controls integrin endocytosis for directional cell migration with aPKC and PAR-3.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009962

Induction of tumor growth by altered stem-cell asymmetric division in Drosophila melanogaster

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009962

Continuing role for mouse Numb and Numbl in maintaining progenitor cells during cortical neurogenesis.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009962

Developmental changes in Notch1 and numb expression mediated by local cell-cell interactions underlie progressively increasing delta sensitivity in neural crest stem cells.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009962

Functional analysis of Cdc42 in actin filament assembly, epithelial morphogenesis, and cell signaling during Drosophila development.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009962

Asymmetric localization of numb autonomously determines sibling neuron identity in the Drosophila CNS.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3009962

Contact-dependent inhibition of cortical neurite growth mediated by notch signaling

27 October 2018

1 reference

PubMed

12 December 2020

Fate determination of neural crest cells by NOTCH-mediated lateral inhibition and asymmetrical cell division during gangliogenesis

1 reference

PubMed

12 December 2020

Calcium regulation of neurite elongation and growth cone motility

1 reference

PubMed

12 December 2020

1 reference

12 December 2020

Identifiers

DOI

10.1186/1749-8104-5-31

1 reference

Dimensions Publication ID

2 August 2017

0 references

1 reference

2 August 2017

1 reference