The response of patients with bile acid diarrhoea to the farnesoid X receptor agonist obeticholic acid. (Q34444158)

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21 February 2020

title

The response of patients with bile acid diarrhoea to the farnesoid X receptor agonist obeticholic acid (English)

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21 February 2020

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ChEBI release 2020-05-28

1

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21 February 2020

Claire Vassie

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21 February 2020

author name string

J D Nolan

3

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21 February 2020

M E Pruzanski

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D A Shapiro

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21 February 2020

I M Johnston

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language of work or name

English

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publication date

20 October 2014

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Alimentary Pharmacology & Therapeutics

21 February 2020

published in

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volume

41

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21 February 2020

page(s)

54-64

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21 February 2020

issue

1

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Idiopathic bile acid catharsis

21 February 2020

cites work

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Defining primary bile acid diarrhea: making the diagnosis and recognizing the disorder.

21 January 2018

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Methods for diagnosis of bile acid malabsorption in clinical practice

21 January 2018

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Systematic review: the prevalence of idiopathic bile acid malabsorption as diagnosed by SeHCAT scanning in patients with diarrhoea-predominant irritable bowel syndrome.

21 January 2018

1 reference

Bile acid diarrhoea and FGF19: new views on diagnosis, pathogenesis and therapy

21 January 2018

1 reference

Increased colonic bile acid exposure: a relevant factor for symptoms and treatment in IBS.

21 January 2018

1 reference

A new mechanism for bile acid diarrhea: defective feedback inhibition of bile acid biosynthesis

21 January 2018

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Chronic diarrhea due to excessive bile acid synthesis and not defective ileal transport: a new syndrome of defective fibroblast growth factor 19 release

21 January 2018

1 reference

Fibroblast growth factor 15 functions as an enterohepatic signal to regulate bile acid homeostasis

21 January 2018

1 reference

Fibroblast Growth Factor 19 and 7α-Hydroxy-4-Cholesten-3-one in the Diagnosis of Patients With Possible Bile Acid Diarrhea.

21 January 2018

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Fibroblast growth factor 19 in patients with bile acid diarrhoea: a prospective comparison of FGF19 serum assay and SeHCAT retention

21 January 2018

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Potent stimulation of fibroblast growth factor 19 expression in the human ileum by bile acids

21 January 2018

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6alpha-ethyl-chenodeoxycholic acid (6-ECDCA), a potent and selective FXR agonist endowed with anticholestatic activity.

21 January 2018

1 reference

Bile acid derivatives as ligands of the farnesoid X receptor. Synthesis, evaluation, and structure-activity relationship of a series of body and side chain modified analogues of chenodeoxycholic acid

21 January 2018

1 reference

New treatment strategies for primary sclerosing cholangitis

21 January 2018

1 reference

Efficacy and safety of the farnesoid X receptor agonist obeticholic acid in patients with type 2 diabetes and nonalcoholic fatty liver disease

21 January 2018

1 reference

Bile acid malabsorption in Crohn's disease and indications for its assessment using SeHCAT

21 January 2018

1 reference

Serum 7 alpha-hydroxy-4-cholesten-3-one and selenohomocholyltaurine (SeHCAT) whole body retention in the assessment of bile acid induced diarrhoea

21 January 2018

1 reference

Circulating intestinal fibroblast growth factor 19 has a pronounced diurnal variation and modulates hepatic bile acid synthesis in man.

21 January 2018

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Pronounced variation in bile acid synthesis in humans is related to gender, hypertriglyceridaemia and circulating levels of fibroblast growth factor 19.

21 January 2018

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Increased bile acid biosynthesis is associated with irritable bowel syndrome with diarrhea

21 January 2018

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Pharmacogenetics of the effects of colesevelam on colonic transit in irritable bowel syndrome with diarrhea

21 January 2018

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Farnesoid X receptor agonists attenuate colonic epithelial secretory function and prevent experimental diarrhoea in vivo

21 January 2018

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Bile acid malabsorption in inflammatory bowel disease: assessment by serum markers.

21 January 2018

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Altered enterohepatic circulation of bile acids in Crohn's disease and their clinical significance: a new perspective.

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1111/APT.12999

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21 February 2020

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