Genome-wide characterization of pancreatic adenocarcinoma patients using next generation sequencing (Q34446744)

2 August 2017

title

Genome-wide characterization of pancreatic adenocarcinoma patients using next generation sequencing (English)

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pancreatic adenocarcinoma

2 August 2017

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Rafael Fonseca

27

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author name string

Winnie S Liang

1

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David W Craig

2

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John Carpten

3

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Mitesh J Borad

4

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Michael J Demeure

5

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Glen J Weiss

6

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Tyler Izatt

7

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Shripad Sinari

8

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Alexis Christoforides

9

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Jessica Aldrich

10

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Ahmet Kurdoglu

11

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Michael Barrett

12

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Lori Phillips

13

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Hollie Benson

14

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Waibhav Tembe

15

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Esteban Braggio

16

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Jeffrey A Kiefer

17

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Christophe Legendre

18

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Richard Posner

19

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Galen H Hostetter

20

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Angela Baker

21

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Jan B Egan

22

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Haiyong Han

23

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Douglas Lake

24

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Edward C Stites

25

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Ramesh K Ramanathan

26

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A Keith Stewart

28

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Daniel Von Hoff

29

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language of work or name

English

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publication date

10 October 2012

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2 August 2017

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volume

7

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issue

10

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page(s)

e43192

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Creative Commons Attribution 4.0 International

2 August 2017

copyright license

start time

10 October 2012

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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describes a project that uses

massive parallel sequencing

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Nuclear protein 1 promotes pancreatic cancer development and protects cells from stress by inhibiting apoptosis

inferred from title

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Increased expression of DNA repair genes in invasive human pancreatic cancer cells

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Genome profiling of pancreatic adenocarcinoma

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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Large regional differences in the frequency of distinct BRCA1/BRCA2 mutations in 517 Dutch breast and/or ovarian cancer families

6 July 2018

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Pancreatic tumours: molecular pathways implicated in ductal cancer are involved in ampullary but not in exocrine nonductal or endocrine tumorigenesis

6 July 2018

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Drg-1 as a differentiation-related, putative metastatic suppressor gene in human colon cancer

6 July 2018

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Database resources of the National Center for Biotechnology Information.

6 July 2018

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Inhibition of tumor cell growth by RTP/rit42 and its responsiveness to p53 and DNA damage

6 July 2018

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Alterations in pancreatic, biliary, and breast carcinomas support MKK4 as a genetically targeted tumor suppressor gene

6 July 2018

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Replacement of Fhit in cancer cells suppresses tumorigenicity

6 July 2018

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Human mitogen-activated protein kinase kinase 4 as a candidate tumor suppressor

6 July 2018

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Amplification of AKT2 in human pancreatic cells and inhibition of AKT2 expression and tumorigenicity by antisense RNA

6 July 2018

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Frequent mutations of CDKN2 in primary pancreatic adenocarcinomas

6 July 2018

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DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1

6 July 2018

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Pancreatic adenocarcinomas frequently show p53 gene mutations.

6 July 2018

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Frequent somatic mutations and homozygous deletions of the p16 (MTS1) gene in pancreatic adenocarcinoma

6 July 2018

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Most human carcinomas of the exocrine pancreas contain mutant c-K-ras genes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3468610

Abnormalities of the p53 tumour suppressor gene in human pancreatic cancer.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3468610

Frequent somatic mutations of the APC gene in human pancreatic cancer

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3468610

APC gene deletions in gastric adenocarcinomas in a Chinese population: a correlation with tumour progression.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3468610

Screening for common copy-number variants in cancer genes.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3468610

Molecular predictors of outcome in a phase 3 study of gemcitabine and erlotinib therapy in patients with advanced pancreatic cancer: National Cancer Institute of Canada Clinical Trials Group Study PA.3.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3468610

Leukemia inhibitory factor receptor (LIFR) is detected as a novel suppressor gene of hepatocellular carcinoma using double-combination array.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3468610

Peroxisome proliferator-activated receptor-gamma and retinoid X receptor-alpha expression in pancreatic ductal adenocarcinoma: association with clinicopathological parameters, tumor proliferative capacity, and patients' survival

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3468610

Different types of K-Ras mutations are conversely associated with overall survival in patients with colorectal cancer.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3468610

The role of epoxide hydrolase Y113H gene variant in pancreatic diseases

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3468610

Expression of MAP4K4 is associated with worse prognosis in patients with stage II pancreatic ductal adenocarcinoma

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3468610

Hedgehog inhibition prolongs survival in a genetically engineered mouse model of pancreatic cancer

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3468610

Sonic hedgehog derived from human pancreatic cancer cells augments angiogenic function of endothelial progenitor cells.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3468610

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3468610

Prediction of survival in diffuse large-B-cell lymphoma based on the expression of six genes

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3468610

Comprehensive analysis of matrix metalloproteinase and tissue inhibitor expression in pancreatic cancer: increased expression of matrix metalloproteinase-7 predicts poor survival.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3468610

Comparative analysis of the EGF-receptor family in pancreatic cancer: expression of HER-4 correlates with a favourable tumor stage

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3468610

Overexpression of the HER-2/neu oncogene in pancreatic adenocarcinoma.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3468610

Expression of matrix metalloproteinases and tissue inhibitors of metalloproteinases in human pancreatic adenocarcinomas: clinicopathologic and prognostic significance of matrilysin expression.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3468610

ErbB-4 mRNA expression is decreased in non-metastatic pancreatic cancer.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3468610

Localization of putative tumor suppressor loci by genome-wide allelotyping in human pancreatic endocrine tumors.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3468610

Frequent codeletion of p16/MTS1 and p15/MTS2 and genetic alterations in p16/MTS1 in pancreatic tumors.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3468610

Mutations of the adenomatous polyposis coli gene in the mutation cluster region: comparison of human pancreatic and colorectal cancers.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3468610

Association of axon guidance factor Semaphorin 3A with poor outcome in pancreatic cancer

27 October 2018

1 reference

12 December 2020

The association between selected risk factors for pancreatic cancer and the expression of p53 and K-ras codon 12 mutations

1 reference

12 December 2020

Prognostic significance of the immediate early response gene X-1 (IEX-1) expression in pancreatic cancer

1 reference

12 December 2020

Frequent amplification of 8q24, 11q, 17q, and 20q-specific genes in pancreatic cancer

1 reference

12 December 2020

BRCA2 germline mutations in familial pancreatic carcinoma

1 reference

12 December 2020

High frequency of Ki-ras codon 12 mutations in pancreatic adenocarcinomas

1 reference

12 December 2020

The c-erb B-2 proto-oncogene in human pancreatic cancer

1 reference

12 December 2020

New tumor suppressor found in pancreatic cancer

1 reference

12 December 2020

Spliceosome mutations in hematopoietic malignancies

1 reference

12 December 2020

Bach1-mediated suppression of p53 is inhibited by p19ARF independently of MDM2

1 reference

12 December 2020

Mutations in FGFR3 and PIK3CA, singly or combined with RAS and AKT1, are associated with AKT but not with MAPK pathway activation in urothelial bladder cancer

1 reference

12 December 2020

DNA copy number changes and evaluation of MYC, IGF1R, and FES amplification in xenografts of pancreatic adenocarcinoma

1 reference

12 December 2020

Copy number of cancer genes predict tumor grade and survival of pancreatic cancer patients

1 reference

12 December 2020

Association of matrilysin mRNA expression with K-ras mutations and progression in pancreatic ductal adenocarcinomas

1 reference

12 December 2020

p53 mutation with frequent novel condons but not a mutator phenotype in BRCA1- and BRCA2-associated breast tumours

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0043192

Identifiers

DOI

1 reference

2 August 2017

0 references

1 reference

2 August 2017

1 reference