IL17: potential therapeutic target in Sjögren's syndrome using adenovirus-mediated gene transfer (Q34448523)

2 August 2017

IL17: potential therapeutic target in Sjögren's syndrome using adenovirus-mediated gene transfer (English)

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2 August 2017

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Cuong Q Nguyen

1

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2 August 2017

Hongen Yin

2

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2 August 2017

Byung Ha Lee

3

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2 August 2017

John A Chiorini

4

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2 August 2017

Ammon B Peck

5

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2 August 2017

20 September 2010

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2 August 2017

Laboratory Investigation

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2 August 2017

91

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2 August 2017

54-62

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2 August 2017

1

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https://scigraph.springernature.com/pub.10.1038/labinvest.2010.164

2 August 2017

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cites work

Receptor-Fc fusion therapeutics, traps, and MIMETIBODY technology

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Interleukin 17 acts in synergy with B cell-activating factor to influence B cell biology and the pathophysiology of systemic lupus erythematosus.

6 July 2018

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Sjögren's syndrome: an old tale with a new twist

6 July 2018

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Unraveling the pathophysiology of Sjogren syndrome-associated dry eye disease

6 July 2018

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Identification of IL-18 and Th17 cells in salivary glands of patients with Sjögren's syndrome, and amplification of IL-17-mediated secretion of inflammatory cytokines from salivary gland cells by IL-18.

6 July 2018

1 reference

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Evaluation of promoters for use in tissue-specific gene delivery

6 July 2018

1 reference

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TGF-beta-induced Foxp3 inhibits T(H)17 cell differentiation by antagonizing RORgammat function

6 July 2018

1 reference

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Salivary gland tissue expression of interleukin-23 and interleukin-17 in Sjögren's syndrome: findings in humans and mice

6 July 2018

1 reference

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Interleukin 17-producing T helper cells and interleukin 17 orchestrate autoreactive germinal center development in autoimmune BXD2 mice

6 July 2018

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Development of Sjogren's syndrome in nonobese diabetic-derived autoimmune-prone C57BL/6.NOD-Aec1Aec2 mice is dependent on complement component-3.

6 July 2018

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IL-4-STAT6 signal transduction-dependent induction of the clinical phase of Sjögren's syndrome-like disease of the nonobese diabetic mouse

6 July 2018

1 reference

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Discovery and biology of IL-23 and IL-27: related but functionally distinct regulators of inflammation

6 July 2018

1 reference

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IL-17 family cytokines and the expanding diversity of effector T cell lineages

6 July 2018

1 reference

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Sjögren's syndrome (SjS)-like disease of mice: the importance of B lymphocytes and autoantibodies

6 July 2018

1 reference

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A genome-wide association study identifies IL23R as an inflammatory bowel disease gene

6 July 2018

1 reference

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Interleukin-23 drives innate and T cell-mediated intestinal inflammation

6 July 2018

1 reference

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The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012147

Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012147

Transforming growth factor-beta induces development of the T(H)17 lineage

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012147

Salivary gland gene therapy

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012147

Toxicity and biodistribution of a first-generation recombinant adenoviral vector, in the presence of hydroxychloroquine, following retroductal delivery to a single rat submandibular gland

6 July 2018

1 reference

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TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells

6 July 2018

1 reference

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Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages

6 July 2018

1 reference

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A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17

6 July 2018

1 reference

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Effect of human vasoactive intestinal peptide gene transfer in a murine model of Sjogren's syndrome

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3012147

Immune responses following salivary gland administration of recombinant adeno-associated virus serotype 2 vectors

6 July 2018

1 reference

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Local adeno-associated virus-mediated interleukin 10 gene transfer has disease-modifying effects in a murine model of Sjögren's syndrome

6 July 2018

1 reference

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Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain

6 July 2018

1 reference

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Requirement of interleukin 17 receptor signaling for lung CXC chemokine and granulocyte colony-stimulating factor expression, neutrophil recruitment, and host defense

6 July 2018

1 reference

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IL-17 stimulates granulopoiesis in mice: use of an alternate, novel gene therapy-derived method for in vivo evaluation of cytokines

6 July 2018

1 reference

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Relationship between the cellular distribution of the alpha(v)beta3/5 integrins and adenoviral infection in salivary glands

6 July 2018

1 reference

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Evidence for the systemic delivery of a transgene product from salivary glands

6 July 2018

1 reference

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Prolonged and effective blockade of tumor necrosis factor activity through adenovirus-mediated gene transfer

6 July 2018

1 reference

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Evidence for antimuscarinic acetylcholine receptor antibody-mediated secretory dysfunction in nod mice

6 July 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2010.164

Gene transfer mediated by different viral vectors following direct cannulation of mouse submandibular salivary glands

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2010.164

Analysis of risk factors for local delivery of low- and intermediate-dose adenovirus gene transfer vectors to individuals with a spectrum of comorbid conditions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2010.164

Safety of local delivery of low- and intermediate-dose adenovirus gene transfer vectors to individuals with a spectrum of morbid conditions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2010.164

Distribution and toxicity resulting from adenoviral vector administration to a single salivary gland in adult rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2010.164

Effect of serotype 5 adenoviral and serotype 2 adeno- associated viral vector-mediated gene transfer to salivary glands on the composition of saliva

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2010.164

Systemic action of human growth hormone following adenovirus-mediated gene transfer to rat submandibular glands

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2010.164

Role of complement and B lymphocytes in Sjögren's syndrome-like autoimmune exocrinopathy of NOD.B10-H2b mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2010.164

Immediate inflammatory responses to adenovirus-mediated gene transfer in rat salivary glands

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20856230

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Serological implications of germinal center-like structures in primary Sjögren's syndrome

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20856230

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/LABINVEST.2010.164

1 reference

Dimensions Publication ID

2 August 2017

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1 reference

2 August 2017

1 reference