Unique and overlapping substrate specificities of caspase-8 and caspase-10. (Q34454210)

2 August 2017

title

Unique and overlapping substrate specificities of caspase-8 and caspase-10. (English)

1 reference

2 August 2017

U Fischer

1

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2 August 2017

C Stroh

series ordinal

2

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2 August 2017

K Schulze-Osthoff

series ordinal

3

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2 August 2017

language of work or name

English

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publication date

1 January 2006

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2 August 2017

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2 August 2017

volume

25

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2 August 2017

issue

1

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2 August 2017

page(s)

152-159

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Granzyme B short-circuits the need for caspase 8 activity during granule-mediated cytotoxic T-lymphocyte killing by directly cleaving Bid.

2 August 2017

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Post-translational modification of Bid has differential effects on its susceptibility to cleavage by caspase 8 or caspase 3.

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Phosphorylation of bid by casein kinases I and II regulates its cleavage by caspase 8.

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Insights into the regulatory mechanism for caspase-8 activation

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Caspase-10 sensitizes breast carcinoma cells to TRAIL-induced but not tumor necrosis factor-induced apoptosis in a caspase-3-dependent manner

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Inhibition of human caspases by peptide-based and macromolecular inhibitors

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RIP and FADD: two "death domain"-containing proteins can induce apoptosis by convergent, but dissociable, pathways

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Fas-associated Death Domain Protein and Caspase-8 Are Not Recruited to the Tumor Necrosis Factor Receptor 1 Signaling Complex during Tumor Necrosis Factor-induced Apoptosis

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Caspase-activated PAK-2 is regulated by subcellular targeting and proteasomal degradation

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Caspase-mediated cleavage of the Ca2+/calmodulin-dependent protein kinase-like kinase facilitates neuronal apoptosis

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Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes

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Caspase-10 triggers Bid cleavage and caspase cascade activation in FasL-induced apoptosis.

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Interchain proteolysis, in the absence of a dimerization stimulus, can initiate apoptosis-associated caspase-8 activation

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Caspase-10 is recruited to and activated at the native TRAIL and CD95 death-inducing signalling complexes in a FADD-dependent manner but can not functionally substitute caspase-8.

21 January 2018

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21 January 2018

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21 January 2018

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Targeted disruption of the mouse Caspase 8 gene ablates cell death induction by the TNF receptors, Fas/Apo1, and DR3 and is lethal prenatally.

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Inherited human Caspase 10 mutations underlie defective lymphocyte and dendritic cell apoptosis in autoimmune lymphoproliferative syndrome type II

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Posttranslational N-myristoylation of BID as a molecular switch for targeting mitochondria and apoptosis

21 January 2018

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Activation of a pro-apoptotic amplification loop through inhibition of NF-kappaB-dependent survival signals by caspase-mediated inactivation of RIP

21 January 2018

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inferred from DOI database lookup

7 January 2021

based on heuristic

Membrane and morphological changes in apoptotic cells regulated by caspase-mediated activation of PAK2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209015

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/SJ.ONC.1209015

1 reference

Dimensions Publication ID

2 August 2017

1034729753

0 references

1 reference