Nonredundant role of Bax and Bak in Bid-mediated apoptosis (Q35150716)

6 August 2017

title

Nonredundant role of Bax and Bak in Bid-mediated apoptosis (English)

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6 August 2017

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Pierre-François Cartron

1

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6 August 2017

Philippe Juin

2

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6 August 2017

Lisa Oliver

3

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6 August 2017

Stéphane Martin

4

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6 August 2017

Khaled Meflah

5

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6 August 2017

François M Vallette

6

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6 August 2017

language of work or name

English

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publication date

1 July 2003

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Molecular and Cellular Biology

6 August 2017

published in

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6 August 2017

volume

23

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6 August 2017

issue

13

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6 August 2017

page(s)

4701-4712

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Functional significance of the perforin/granzyme cell death pathway

6 August 2017

cites work

1 reference

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BAX and BAK mediate p53-independent suppression of tumorigenesis

28 July 2018

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The Bcl2 family: regulators of the cellular life-or-death switch

28 July 2018

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c-Myc functionally cooperates with Bax to induce apoptosis

28 July 2018

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28 July 2018

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28 July 2018

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The expression of a new variant of the pro-apoptotic molecule Bax, Baxpsi, is correlated with an increased survival of glioblastoma multiforme patients

28 July 2018

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28 July 2018

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28 July 2018

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Granzyme B can cause mitochondrial depolarization and cell death in the absence of BID, BAX, and BAK.

28 July 2018

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Resistance to granzyme B-mediated cytochrome c release in Bak-deficient cells

28 July 2018

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Bax loss impairs Myc-induced apoptosis and circumvents the selection of p53 mutations during Myc-mediated lymphomagenesis

28 July 2018

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BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak

28 July 2018

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Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death

28 July 2018

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28 July 2018

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Inactivation of the apoptosis effector Apaf-1 in malignant melanoma

28 July 2018

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Pro-apoptotic cascade activates BID, which oligomerizes BAK or BAX into pores that result in the release of cytochrome c.

28 July 2018

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Role of BAX in the apoptotic response to anticancer agents

28 July 2018

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Mutational inactivation of the proapoptotic gene BAX confers selective advantage during tumor clonal evolution

28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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Bid induces the oligomerization and insertion of Bax into the outer mitochondrial membrane

28 July 2018

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Bid-deficient mice are resistant to Fas-induced hepatocellular apoptosis

28 July 2018

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Haploid loss of bax leads to accelerated mammary tumor development in C3(1)/SV40-TAg transgenic mice: reduction in protective apoptotic response at the preneoplastic stage

28 July 2018

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Bid-induced conformational change of Bax is responsible for mitochondrial cytochrome c release during apoptosis

28 July 2018

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Caspase cleaved BID targets mitochondria and is required for cytochrome c release, while BCL-XL prevents this release but not tumor necrosis factor-R1/Fas death

28 July 2018

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Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=164853

Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors

28 July 2018

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Hematopoietic malignancies demonstrate loss-of-function mutations of BAX

28 July 2018

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28 July 2018

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Death and anti-death: tumour resistance to apoptosis

28 July 2018

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Tumor-cell resistance to death receptor--induced apoptosis through mutational inactivation of the proapoptotic Bcl-2 homolog Bax.

27 September 2018

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Involvement of the N-terminus of Bax in its intracellular localization and function.

27 September 2018

1 reference

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BCL-2, BCL-X(L) sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis

27 September 2018

1 reference

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Granzyme B-mediated apoptosis proceeds predominantly through a Bcl-2-inhibitable mitochondrial pathway

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=164853

Aberrant patterns of DNA methylation, chromatin formation and gene expression in cancer

27 September 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=164853

Initiation of apoptosis by granzyme B requires direct cleavage of bid, but not direct granzyme B-mediated caspase activation.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=164853

tBID, a membrane-targeted death ligand, oligomerizes BAK to release cytochrome c

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=164853

Granzyme B short-circuits the need for caspase 8 activity during granule-mediated cytotoxic T-lymphocyte killing by directly cleaving Bid.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=164853

Bax degradation by the ubiquitin/proteasome-dependent pathway: involvement in tumor survival and progression

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=164853

Bax suppresses tumorigenesis and stimulates apoptosis in vivo

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=164853

Somatic frameshift mutations in the BAX gene in colon cancers of the microsatellite mutator phenotype.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=164853

Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=164853

Different expression patterns of Bcl-2 family genes in breast cancer by estrogen receptor status with special reference to pro-apoptotic Bak gene

27 September 2018

1 reference

12 December 2020

BCL-2 gene family and the regulation of programmed cell death

1 reference

12 December 2020

The C-terminus of bax is not a membrane addressing/anchoring signal

1 reference

12 December 2020

Loss of Bax alters tumor spectrum and tumor numbers in ARF-deficient mice

1 reference

12 December 2020

10.1128/MCB.23.13.4701-4712.2003

Identifiers

DOI

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6 August 2017

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6 August 2017

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